ID B0X8Y0_CULQU Unreviewed; 1769 AA.
AC B0X8Y0;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EDS42736.1, ECO:0000313|EnsemblMetazoa:CPIJ015813-PA};
GN Name=6049318 {ECO:0000313|EnsemblMetazoa:CPIJ015813-PA};
GN ORFNames=CpipJ_CPIJ015813 {ECO:0000313|EMBL:EDS42736.1};
OS Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Culicini; Culex; Culex.
OX NCBI_TaxID=7176;
RN [1] {ECO:0000313|EMBL:EDS42736.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHB {ECO:0000313|EMBL:EDS42736.1};
RG The Broad Institute Genome Sequencing Platform;
RA Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT "Annotation of Culex pipiens quinquefasciatus.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:CPIJ015813-PA}
RP IDENTIFICATION.
RC STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ015813-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
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DR EMBL; DS232509; EDS42736.1; -; Genomic_DNA.
DR RefSeq; XP_001866102.1; XM_001866067.1.
DR STRING; 7176.B0X8Y0; -.
DR EnsemblMetazoa; CPIJ015813-RA; CPIJ015813-PA; CPIJ015813.
DR KEGG; cqu:CpipJ_CPIJ015813; -.
DR VEuPathDB; VectorBase:CPIJ015813; -.
DR VEuPathDB; VectorBase:CQUJHB000856; -.
DR eggNOG; ENOG502QS7I; Eukaryota.
DR HOGENOM; CLU_238875_0_0_1; -.
DR InParanoid; B0X8Y0; -.
DR OrthoDB; 119290at2759; -.
DR Proteomes; UP000002320; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0017038; P:protein import; IEA:InterPro.
DR GO; GO:0006605; P:protein targeting; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR Gene3D; 3.90.1440.10; SecA, preprotein cross-linking domain; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR032871; AHH_dom_containing.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000185; SecA.
DR InterPro; IPR011115; SecA_DEAD.
DR InterPro; IPR014018; SecA_motor_DEAD.
DR InterPro; IPR036670; SecA_X-link_sf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR30612:SF0; CHLOROPLAST PROTEIN-TRANSPORTING ATPASE; 1.
DR PANTHER; PTHR30612; SECA INNER MEMBRANE COMPONENT OF SEC PROTEIN SECRETION SYSTEM; 1.
DR Pfam; PF14412; AHH; 1.
DR Pfam; PF07517; SecA_DEAD; 1.
DR SMART; SM00957; SecA_DEAD; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF81767; Pre-protein crosslinking domain of SecA; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51196; SECA_MOTOR_DEAD; 1.
DR PROSITE; PS50005; TPR; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339};
KW Translocation {ECO:0000256|ARBA:ARBA00023010};
KW Transport {ECO:0000256|ARBA:ARBA00022927}.
FT DOMAIN 1..712
FT /note="SecA family profile"
FT /evidence="ECO:0000259|PROSITE:PS51196"
FT DOMAIN 163..271
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 558..724
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REPEAT 895..928
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 139..159
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1437..1464
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1611..1630
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1769 AA; 199425 MW; 321F86CFBA01651B CRC64;
MEQSYLSLKT AEGYTAHILR AGDTYGAIVM DNTIARCCQV FEVPVKVGFP FSENAIIPLE
INPKHVHLLC ASGQRVLFIG RLGLHGGGHS QSCSGNHVQS IIVPNVTILV QTVDAWSIAH
IFQDTIVLGE LRKRKKGSES RSFCDRKPRD GAVNRKKKKK KLKRGKKVDV VTTSTELSKR
EVERQRAFFE MLQLTVDENS SGRDKKTIYS CDVVYGTASD FQGDILRTEF LGNDCRGNRK
FEVVIVDEVD SMLFDSRSHS VRLADQCPGM THLEVPLAVV WQFIHHTNQH MISKNGKVYF
IAEDFEVHGH DVKLLSGENW LTAATEVDDK KEFIIEHGQK HLQKLLRELA EDEKCEYQTY
QDLNLKILAK EQEISLDSSN DQLKKECDKL RAELFQLPWN RRHPIIDIPE HLRAFALTQI
PSWIKNAIQA AWGFQQDAHY AVMNGKIVPI YFKETGVLQS NMVWSDGLTQ FLQLKEGLCM
DPEAVSTNFI SNVSFFNRYG SNVFGLTGTL GEESTQQFLR SMYGTDMVII PPHKQVEIHN
NQDSPYRCKE LMPLVCPNVG MWYKTIKENA LYHASSNRGV LIIWQYIFQV EHICNMLKKV
YDPEKIHKYT GTDATFDKTT IDSGEIILAT NIAGRGTDFK TSQEVEHHGG MCVIVTFLPE
SNRVEMQNVG RTAREGKRGM AQLIVLDKNN TPMDTLKTLR SLNETEADEK ATDEAKRMLV
QDALFQRFCT LENKFLPSHD VVRNVQLWNL LQINWAIFSS DHLNARKIAE ESRKLELKTI
KEYINKMKGK KLEMLTKEEI DTTVSEEVAS MKPKFEALYI QSKRNEFCQQ QSSHMPKELI
DCFRANKAYE PFITKDARDF KWTLYDRKGA EESWGMWLKS KHFVENEATE DQATKMFEEE
FGNDALDRKD VEAAINCYDR AIQLDPTFSV NARYNKAQAL LTYAENKLSR QDEAKKELQK
AKDMITAGTC SEYASQHVQH QLNILSKQEE YIVRALEMLD QALKNKNNVK LTLKKMPTVL
SEAKEDHGKA IQEAAQNGLT HLFMVEEELP RPWGSIISIA FIGISQIAAG CLIVACTGGA
LGTGLIAEGV SDMITSVRSA ITGTFSWAAW AAQKVISLAV SIVCAGFSGI KSGMKAVVNT
VKDLRKGVQM AKGGIELAVK EVSLAIGKGI VKECLTEGGK YCTDLTIMNK VEEMISQKVG
ERLTAALLKN DLIVAALKDD EANGSNYWKQ KFISDGLDIL KDERMNECLK LLKEIAKGIA
SRQIPLASDI LTYSGVLVFL KVLMTYTEDF IKKFNKQVSN HRSEINSIAG ANSNPQQTTP
QSMLVSQTHQ HTLISNAPNV DVEAEDIIVH TLQDDTSYSS KCTFGNKQLQ SNYVEASTPE
SLANAFKSRI AGKLAASARE SIVNPALSNA TSFVTTKLFT SCENSVAELR KEIKTARDKR
SCDNDLANTG RKQPDKQHKQ EDLGEHSKKA IKELSTEGIA HDTTILALAA AETNCPIYVY
DEKGNLKDVL GDNLSGDPIS LIHSPPSEER PLGHFEPLNP NVEVTPSGIN TCAFDSVFAQ
LSQEQKDSLK LNDPSDLRER LVQRINSNPA EAERAFSKRA ELTKIASDRI LRGGARKLPP
EEKRKKQTKE QFDDLLHEMD YESDSHTVDE AVEQKKCQKH HILHRKFKNH PALVKANFHI
DDPSNLIYLP ISEEIRSECG TQRSIHRGRH SNLEFNRVNN GLDKIYQDAT ANNWSQQETF
KAVFRFAMDG RTGLRKGIID LYEKEQREE
//
