ID   B0XAU1_CULQU            Unreviewed;       442 AA.
AC   B0XAU1;
DT   08-APR-2008, integrated into UniProtKB/TrEMBL.
DT   08-APR-2008, sequence version 1.
DT   24-JAN-2024, entry version 85.
DE   SubName: Full=Liprin alpha {ECO:0000313|EMBL:EDS43880.1, ECO:0000313|EnsemblMetazoa:CPIJ016635-PA};
GN   Name=6050100 {ECO:0000313|EnsemblMetazoa:CPIJ016635-PA};
GN   ORFNames=CpipJ_CPIJ016635 {ECO:0000313|EMBL:EDS43880.1};
OS   Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Culicini; Culex; Culex.
OX   NCBI_TaxID=7176;
RN   [1] {ECO:0000313|EMBL:EDS43880.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB {ECO:0000313|EMBL:EDS43880.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA   Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA   Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA   Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA   Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA   Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA   Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA   Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:CPIJ016635-PA}
RP   IDENTIFICATION.
RC   STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ016635-PA};
RG   EnsemblMetazoa;
RL   Submitted (FEB-2021) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the liprin family. Liprin-alpha subfamily.
CC       {ECO:0000256|ARBA:ARBA00007026}.
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DR   EMBL; DS232596; EDS43880.1; -; Genomic_DNA.
DR   RefSeq; XP_001866763.1; XM_001866728.1.
DR   AlphaFoldDB; B0XAU1; -.
DR   STRING; 7176.B0XAU1; -.
DR   EnsemblMetazoa; CPIJ016635-RA; CPIJ016635-PA; CPIJ016635.
DR   KEGG; cqu:CpipJ_CPIJ016635; -.
DR   VEuPathDB; VectorBase:CPIJ016635; -.
DR   VEuPathDB; VectorBase:CQUJHB009484; -.
DR   eggNOG; KOG0249; Eukaryota.
DR   HOGENOM; CLU_620025_0_0_1; -.
DR   InParanoid; B0XAU1; -.
DR   OrthoDB; 2906732at2759; -.
DR   Proteomes; UP000002320; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   CDD; cd09562; SAM_liprin-alpha1_2_3_4_repeat1; 1.
DR   CDD; cd09565; SAM_liprin-alpha1_2_3_4_repeat2; 1.
DR   CDD; cd09568; SAM_liprin-alpha1_2_3_4_repeat3; 1.
DR   Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 3.
DR   InterPro; IPR029515; Liprin.
DR   InterPro; IPR037620; Liprin-alpha_SAM_rpt_1.
DR   InterPro; IPR037621; Liprin-alpha_SAM_rpt_2.
DR   InterPro; IPR037622; Liprin-alpha_SAM_rpt_3.
DR   InterPro; IPR001660; SAM.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   PANTHER; PTHR12587; LAR INTERACTING PROTEIN LIP -RELATED PROTEIN; 1.
DR   PANTHER; PTHR12587:SF20; LIPRIN-ALPHA, ISOFORM E; 1.
DR   Pfam; PF00536; SAM_1; 2.
DR   Pfam; PF07647; SAM_2; 1.
DR   SMART; SM00454; SAM; 3.
DR   SUPFAM; SSF47769; SAM/Pointed domain; 3.
DR   PROSITE; PS50105; SAM_DOMAIN; 3.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002320}.
FT   DOMAIN          187..253
FT                   /note="SAM"
FT                   /evidence="ECO:0000259|PROSITE:PS50105"
FT   DOMAIN          280..336
FT                   /note="SAM"
FT                   /evidence="ECO:0000259|PROSITE:PS50105"
FT   DOMAIN          360..429
FT                   /note="SAM"
FT                   /evidence="ECO:0000259|PROSITE:PS50105"
SQ   SEQUENCE   442 AA;  49670 MW;  258256BE27AE3F8A CRC64;
     MFETLIRPVI LYGHETWTRI CKRLKFSKEE CLGRSLAACP SIRNSGRNAG RIRWAGHVAR
     MPNALDARQP NQTINPVKLV FISEQQECGG WGATGEVVRP SGERVGKCRG CKTGKDSGMS
     DGSVSMMSMS GLSLISDIDS TYDTIAAHKV TGKNTSVDYC RQKKKEHDYR HDLLGEAMKA
     GTPFALWNGP TIVAWLELWV GMPAWYVAAC RANVKSGAIM SALSDTEIQR EIGISNPLHR
     LKLRLAIQEM VCLTSPSAPQ TTRSTLAFGD MNHEWIGNYW LPGLGLPQYR TTFMECLVDA
     RMLDHLNKKD LRGQLKMVDS FHRTSLQYGI SCLKRLNYDR NALEERRKTT ENSMDDVLVW
     SNDRVMRWIH SIGLKEYSNN LLESGVHGAL LALDESFDAN SLALALQIPT QNIQARQTLE
     SEFNKLLEVA TNRRIDTEQM KS
//