ID B0XAZ0_CULQU Unreviewed; 448 AA.
AC B0XAZ0;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 99.
DE SubName: Full=Integrin-linked protein kinase {ECO:0000313|EMBL:EDS43960.1, ECO:0000313|EnsemblMetazoa:CPIJ016644-PA};
GN Name=6050160 {ECO:0000313|EnsemblMetazoa:CPIJ016644-PA};
GN ORFNames=CpipJ_CPIJ016644 {ECO:0000313|EMBL:EDS43960.1};
OS Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Culicini; Culex; Culex.
OX NCBI_TaxID=7176;
RN [1] {ECO:0000313|EMBL:EDS43960.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHB {ECO:0000313|EMBL:EDS43960.1};
RG The Broad Institute Genome Sequencing Platform;
RA Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT "Annotation of Culex pipiens quinquefasciatus.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:CPIJ016644-PA}
RP IDENTIFICATION.
RC STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ016644-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
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DR EMBL; DS232603; EDS43960.1; -; Genomic_DNA.
DR RefSeq; XP_001866812.1; XM_001866777.1.
DR AlphaFoldDB; B0XAZ0; -.
DR STRING; 7176.B0XAZ0; -.
DR EnsemblMetazoa; CPIJ016644-RA; CPIJ016644-PA; CPIJ016644.
DR GeneID; 6050160; -.
DR KEGG; cqu:CpipJ_CPIJ016644; -.
DR VEuPathDB; VectorBase:CPIJ016644; -.
DR VEuPathDB; VectorBase:CQUJHB001588; -.
DR eggNOG; KOG0195; Eukaryota.
DR HOGENOM; CLU_000288_7_5_1; -.
DR InParanoid; B0XAZ0; -.
DR OMA; NEHGNAP; -.
DR OrthoDB; 2127408at2759; -.
DR Proteomes; UP000002320; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR PANTHER; PTHR23257:SF967; INTEGRIN-LINKED PROTEIN KINASE; 1.
DR PANTHER; PTHR23257; SERINE-THREONINE PROTEIN KINASE; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR PIRSF; PIRSF000654; Integrin-linked_kinase; 1.
DR SMART; SM00248; ANK; 3.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50297; ANK_REP_REGION; 3.
DR PROSITE; PS50088; ANK_REPEAT; 3.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Integrin {ECO:0000313|EMBL:EDS43960.1};
KW Kinase {ECO:0000313|EMBL:EDS43960.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW Transferase {ECO:0000313|EMBL:EDS43960.1}.
FT REPEAT 33..65
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 66..98
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 99..131
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 192..443
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
SQ SEQUENCE 448 AA; 50806 MW; 0E928845102E4921 CRC64;
MEDIFHWCRE GNSIQVRLWL DDTEHDMNQG DDHGFSPLHW CAKEGHTKLV EMLLHRGARV
NATNMGDDIP LHLAAAHGHL EIVQMLVRHR SDVNAANEHG NTPLHYACFW GYQPIAEELV
SNGALVSLAN KDGDTPLDKA KASVATRLHN LAVESGQELK KISFKDQSWL GMKTRSRDAT
LSRFKGINIQ DLMLHTKLAI TPGGETWRGR WQNNDIVAKI LAIRECNARV SRDFNEEFPK
LRIFSHPNIL PVIGACNAPP RLIVISQYMP RGSLYDLLHG AAGIVVDTAQ AVRFALDIAR
GMAYLHSLER IIPEYHLNSF HVMIDDDLTA RVNMADAKFS FQERGRSYQP AWMSPEMLQK
KRSERNWEAC DMWSFAICIW ELATREVPFA ELSPMEAGMR IATEGLRVTI PPGTSPHLTK
LIRICMNEDP GKRPKFDMIV PILEKMKR
//
