UniProt: B0XHF1

Database: UniProt
Entry: B0XHF1_CULQU

LinkDB:  B0XHF1_CULQU 
Original site:  B0XHF1_CULQU

All links

Ontology (3)   
   GO (3)   
Gene (2)   
   KEGG GENES (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   EMBL (1)   
Protein domain (3)   
   InterPro (1)   
   Pfam (1)   
   PROSITE (1)   
All databases (10)   

Download RDF

ID   B0XHF1_CULQU            Unreviewed;       372 AA.
AC   B0XHF1;
DT   08-APR-2008, integrated into UniProtKB/TrEMBL.
DT   08-APR-2008, sequence version 1.
DT   27-MAR-2024, entry version 72.
DE   RecName: Full=Innexin {ECO:0000256|RuleBase:RU010713};
GN   Name=6052895 {ECO:0000313|EnsemblMetazoa:CPIJ018867-PA};
GN   Synonyms=inx {ECO:0000256|RuleBase:RU010713};
GN   ORFNames=CpipJ_CPIJ018867 {ECO:0000313|EMBL:EDS28380.1};
OS   Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Culicini; Culex; Culex.
OX   NCBI_TaxID=7176;
RN   [1] {ECO:0000313|EMBL:EDS28380.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB {ECO:0000313|EMBL:EDS28380.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA   Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA   Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA   Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA   Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA   Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA   Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA   Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:CPIJ018867-PA}
RP   IDENTIFICATION.
RC   STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ018867-PA};
RG   EnsemblMetazoa;
RL   Submitted (FEB-2021) to UniProtKB.
CC   -!- FUNCTION: Structural component of the gap junctions.
CC       {ECO:0000256|RuleBase:RU010713}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU010713};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU010713}. Cell
CC       junction, gap junction {ECO:0000256|RuleBase:RU010713}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the pannexin family. {ECO:0000256|PROSITE-
CC       ProRule:PRU00351, ECO:0000256|RuleBase:RU010713}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DS233153; EDS28380.1; -; Genomic_DNA.
DR   RefSeq; XP_001869073.1; XM_001869038.1.
DR   AlphaFoldDB; B0XHF1; -.
DR   STRING; 7176.B0XHF1; -.
DR   EnsemblMetazoa; CPIJ018867-RA; CPIJ018867-PA; CPIJ018867.
DR   GeneID; 6052895; -.
DR   KEGG; cqu:CpipJ_CPIJ018867; -.
DR   VEuPathDB; VectorBase:CPIJ018867; -.
DR   VEuPathDB; VectorBase:CQUJHB009164; -.
DR   eggNOG; ENOG502QWRS; Eukaryota.
DR   HOGENOM; CLU_035763_1_1_1; -.
DR   InParanoid; B0XHF1; -.
DR   OMA; PIHCEAS; -.
DR   OrthoDB; 2873211at2759; -.
DR   Proteomes; UP000002320; Unassembled WGS sequence.
DR   GO; GO:0005921; C:gap junction; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0034220; P:monoatomic ion transmembrane transport; IEA:UniProtKB-KW.
DR   InterPro; IPR000990; Innexin.
DR   PANTHER; PTHR11893; INNEXIN; 1.
DR   PANTHER; PTHR11893:SF40; INNEXIN SHAKING-B; 1.
DR   Pfam; PF00876; Innexin; 1.
DR   PRINTS; PR01262; INNEXIN.
DR   PROSITE; PS51013; PANNEXIN; 1.
PE   3: Inferred from homology;
KW   Cell junction {ECO:0000256|RuleBase:RU010713};
KW   Gap junction {ECO:0000256|ARBA:ARBA00022868, ECO:0000256|PROSITE-
KW   ProRule:PRU00351}; Ion channel {ECO:0000256|RuleBase:RU010713};
KW   Ion transport {ECO:0000256|RuleBase:RU010713};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW   ProRule:PRU00351}; Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW   ProRule:PRU00351};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|PROSITE-
KW   ProRule:PRU00351}; Transport {ECO:0000256|RuleBase:RU010713}.
FT   TRANSMEM        23..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00351,
FT                   ECO:0000256|RuleBase:RU010713"
FT   TRANSMEM        109..126
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00351,
FT                   ECO:0000256|RuleBase:RU010713"
FT   TRANSMEM        179..198
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00351,
FT                   ECO:0000256|RuleBase:RU010713"
FT   TRANSMEM        268..295
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00351,
FT                   ECO:0000256|RuleBase:RU010713"
SQ   SEQUENCE   372 AA;  44422 MW;  4412FCF95C4B4D36 CRC64;
     MLDIFRGLKS LVKISHVNTD SPVFRLHYSI TVMILMSFSL IVTTKQYVGN PIDCVHTKDI
     PEEVLNTYCW IHSTYALKSL FLKKVGSEVP YPGVGNSDGK SLDKKIYKYY QWVCFCLFFQ
     AILFYTPRWL WKSWEGGKIH ALMMDLDIGI CSEIEKKQKK KLLLDYLWDN LRYHNWWAYR
     YYICELLSLI NVIGQMFLMN RFFDGEFMTF GLDVIAHMEA DQEDRMDPMI YIFPRMTKCT
     FYKYGVSGEV ERHDAICILP LNVVNEKIYI FLWFWFIILT ILTTLTIFYR IIIIFSPRMR
     VYLLRLRFRL VRRDAIEIIV RRSKMGDWFL LYRLGENLDS IIFRDVMQDL ANRLHNNQHH
     RVPGMKGEIQ DA
//

DBGET integrated database retrieval system