ID   B0XJP0_CULQU            Unreviewed;       248 AA.
AC   B0XJP0;
DT   08-APR-2008, integrated into UniProtKB/TrEMBL.
DT   08-APR-2008, sequence version 1.
DT   27-MAR-2024, entry version 95.
DE   SubName: Full=Kinesin heavy chain {ECO:0000313|EMBL:EDS30579.1, ECO:0000313|EnsemblMetazoa:CPIJ019631-PA};
GN   Name=6053847 {ECO:0000313|EnsemblMetazoa:CPIJ019631-PA};
GN   ORFNames=CpipJ_CPIJ019631 {ECO:0000313|EMBL:EDS30579.1};
OS   Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Culicini; Culex; Culex.
OX   NCBI_TaxID=7176;
RN   [1] {ECO:0000313|EMBL:EDS30579.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB {ECO:0000313|EMBL:EDS30579.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA   Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA   Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA   Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA   Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA   Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA   Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA   Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:CPIJ019631-PA}
RP   IDENTIFICATION.
RC   STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ019631-PA};
RG   EnsemblMetazoa;
RL   Submitted (FEB-2021) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC       superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00283}.
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DR   EMBL; DS233572; EDS30579.1; -; Genomic_DNA.
DR   RefSeq; XP_001869862.1; XM_001869827.1.
DR   AlphaFoldDB; B0XJP0; -.
DR   STRING; 7176.B0XJP0; -.
DR   EnsemblMetazoa; CPIJ019631-RA; CPIJ019631-PA; CPIJ019631.
DR   KEGG; cqu:CpipJ_CPIJ019631; -.
DR   VEuPathDB; VectorBase:CPIJ019631; -.
DR   VEuPathDB; VectorBase:CQUJHB013898; -.
DR   eggNOG; KOG0244; Eukaryota.
DR   HOGENOM; CLU_001485_2_0_1; -.
DR   InParanoid; B0XJP0; -.
DR   OMA; YVQLSQH; -.
DR   OrthoDB; 3028456at2759; -.
DR   Proteomes; UP000002320; Unassembled WGS sequence.
DR   GO; GO:0015630; C:microtubule cytoskeleton; IEA:UniProt.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR   InterPro; IPR027640; Kinesin-like_fam.
DR   InterPro; IPR001752; Kinesin_motor_dom.
DR   InterPro; IPR036961; Kinesin_motor_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR47969; CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED; 1.
DR   PANTHER; PTHR47969:SF15; ZGC:66125; 1.
DR   Pfam; PF00225; Kinesin; 1.
DR   PRINTS; PR00380; KINESINHEAVY.
DR   SMART; SM00129; KISc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002320}.
FT   DOMAIN          1..229
FT                   /note="Kinesin motor"
FT                   /evidence="ECO:0000259|PROSITE:PS50067"
SQ   SEQUENCE   248 AA;  27415 MW;  550C26F3A9095F9B CRC64;
     MGLQWDHSGP HDINRGMITR ALDQTFELLR EARNKEDYEI EVSFIEIYNE KIYDLLSENS
     TEPVNTRGCK FNGGTKRQVT RADQAQDILL EGNKNRHVRP TKMNTLSSRS HAIFSIHASV
     VHDDARIVSA LHLVDLAGSE GVRRTGHQGA ALAEGVHINQ GLLSIGKVLQ ALSIGSKVIP
     YRDSILSTVL QDSLNSNSYL TLLACISPMP EDLSETLSTI RFAQGAKTLK NNPQINLVAA
     ELKICQFV
//