ID B0XKK6_CULQU Unreviewed; 338 AA.
AC B0XKK6;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 91.
DE SubName: Full=Triacylglycerol lipase {ECO:0000313|EMBL:EDS32057.1};
GN Name=6054227 {ECO:0000313|EnsemblMetazoa:CPIJ019917-PA};
GN ORFNames=CpipJ_CPIJ019917 {ECO:0000313|EMBL:EDS32057.1};
OS Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Culicini; Culex; Culex.
OX NCBI_TaxID=7176;
RN [1] {ECO:0000313|EMBL:EDS32057.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHB {ECO:0000313|EMBL:EDS32057.1};
RG The Broad Institute Genome Sequencing Platform;
RA Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT "Annotation of Culex pipiens quinquefasciatus.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:CPIJ019917-PA}
RP IDENTIFICATION.
RC STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ019917-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily. Lipase family.
CC {ECO:0000256|ARBA:ARBA00010701, ECO:0000256|RuleBase:RU004262}.
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DR EMBL; DS233875; EDS32057.1; -; Genomic_DNA.
DR RefSeq; XP_001870178.1; XM_001870143.1.
DR AlphaFoldDB; B0XKK6; -.
DR STRING; 7176.B0XKK6; -.
DR EnsemblMetazoa; CPIJ019917-RA; CPIJ019917-PA; CPIJ019917.
DR KEGG; cqu:CpipJ_CPIJ019917; -.
DR VEuPathDB; VectorBase:CPIJ019917; -.
DR VEuPathDB; VectorBase:CQUJHB003905; -.
DR eggNOG; ENOG502RYX8; Eukaryota.
DR HOGENOM; CLU_027171_2_3_1; -.
DR InParanoid; B0XKK6; -.
DR OMA; FERMYES; -.
DR OrthoDB; 3448680at2759; -.
DR Proteomes; UP000002320; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016298; F:lipase activity; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR013818; Lipase.
DR InterPro; IPR000734; TAG_lipase.
DR PANTHER; PTHR11610; LIPASE; 1.
DR PANTHER; PTHR11610:SF173; LIPASE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR Pfam; PF00151; Lipase; 1.
DR PRINTS; PR00821; TAGLIPASE.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..338
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5011409523"
FT DOMAIN 55..317
FT /note="Lipase"
FT /evidence="ECO:0000259|Pfam:PF00151"
SQ SEQUENCE 338 AA; 36918 MW; 35E59D6FF93A8A34 CRC64;
MWQLVTLALF AASIFVGSAA QLKLDMSDKS EAELLALMDD MTKLLNVQKA KLPGPIDQEV
RFFCSNRQGA AFSQVMLNDQ GLLAKMSMQK PVAFVIHGWT SSSQEAHFRD LAGNYSRYVD
SNVCLVDWAN LAAYSYDVAS GQSIRMTANY LTRFVRFLNL NGIGYAKVTL IGHSLGAHIS
GFVGKNLGGE VGQIFALDPA GVMFTMPEDV GESNRLTKSD AKFVQVIYTT QGTLAMGISA
GHQNLWMNNN GMYPQPGCKK VGEGKGLFSK TVAELTCSHT MSVAMFLAAL DPKVEFTMKR
CSNYWLYNIG MCALATKDKL GIWSKSQSFE GILENALG
//
