ID B1A013_SALSA Unreviewed; 490 AA.
AC B1A013;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=CD4-1-like protein {ECO:0000313|EMBL:ABZ81916.1};
DE SubName: Full=CD4-like protein isoform 1 precursor {ECO:0000313|RefSeq:NP_001117083.1};
DE SubName: Full=CD4-like protein isoform X1 {ECO:0000313|RefSeq:XP_014019014.1, ECO:0000313|RefSeq:XP_014019021.1};
GN Name=LOC100136502 {ECO:0000313|RefSeq:NP_001117083.1,
GN ECO:0000313|RefSeq:XP_014019014.1, ECO:0000313|RefSeq:XP_014019021.1,
GN ECO:0000313|RefSeq:XP_014019030.1, ECO:0000313|RefSeq:XP_014019036.1,
GN ECO:0000313|RefSeq:XP_014019043.1, ECO:0000313|RefSeq:XP_014019051.1,
GN ECO:0000313|RefSeq:XP_014019061.1, ECO:0000313|RefSeq:XP_014019071.1,
GN ECO:0000313|RefSeq:XP_014019078.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|EMBL:ABZ81916.1};
RN [1] {ECO:0000313|RefSeq:NP_001117083.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=17241401; DOI=10.1111/j.1365-2761.2007.00769.x;
RA Bakke-McKellep A.M., Froystad M.K., Lilleeng E., Dapra F., Refstie S.,
RA Krogdahl A., Landsverk T.;
RT "Response to soy: T-cell-like reactivity in the intestine of Atlantic
RT salmon, Salmo salar L.";
RL J. Fish Dis. 30:13-25(2007).
RN [2] {ECO:0000313|EMBL:ABZ81916.1, ECO:0000313|RefSeq:NP_001117083.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=18983924; DOI=10.1016/j.fsi.2008.09.019;
RA Moore L.J., Dijkstra J.M., Koppang E.O., Hordvik I.;
RT "CD4 homologues in Atlantic salmon.";
RL Fish Shellfish Immunol. 26:10-18(2009).
RN [3] {ECO:0000313|RefSeq:NP_001117083.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=20723604; DOI=10.1016/j.fsi.2010.08.001;
RA Maisey K., Imarai M.;
RT "Diversity of teleost leukocyte molecules: role of alternative splicing.";
RL Fish Shellfish Immunol. 31:663-672(2011).
RN [4] {ECO:0000313|RefSeq:NP_001117083.1, ECO:0000313|RefSeq:XP_014019014.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_014019014.1,
RC ECO:0000313|RefSeq:XP_014019021.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004251};
CC Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
CC Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane
CC protein {ECO:0000256|ARBA:ARBA00004479}.
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DR EMBL; EU409794; ABZ81916.1; -; mRNA.
DR EMBL; EU585750; ACB88037.1; -; Genomic_DNA.
DR RefSeq; NP_001117083.1; NM_001123611.1.
DR RefSeq; XP_014019014.1; XM_014163539.1.
DR RefSeq; XP_014019021.1; XM_014163546.1.
DR RefSeq; XP_014019030.1; XM_014163555.1.
DR RefSeq; XP_014019036.1; XM_014163561.1.
DR RefSeq; XP_014019043.1; XM_014163568.1.
DR RefSeq; XP_014019051.1; XM_014163576.1.
DR RefSeq; XP_014019061.1; XM_014163586.1.
DR RefSeq; XP_014019071.1; XM_014163596.1.
DR RefSeq; XP_014019078.1; XM_014163603.1.
DR STRING; 8030.ENSSSAP00000106374; -.
DR PaxDb; 8030-ENSSSAP00000106374; -.
DR GeneID; 100136502; -.
DR KEGG; sasa:100136502; -.
DR OrthoDB; 4126583at2759; -.
DR Proteomes; UP000087266; Chromosome ssa02.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 4.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013151; Immunoglobulin.
DR PANTHER; PTHR11422; T-CELL SURFACE GLYCOPROTEIN CD4; 1.
DR PANTHER; PTHR11422:SF8; T-CELL SURFACE GLYCOPROTEIN CD4; 1.
DR Pfam; PF00047; ig; 1.
DR SMART; SM00409; IG; 4.
DR SUPFAM; SSF48726; Immunoglobulin; 4.
DR PROSITE; PS50835; IG_LIKE; 3.
PE 2: Evidence at transcript level;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Signal {ECO:0000256|SAM:SignalP, ECO:0000313|RefSeq:NP_001117083.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..490
FT /evidence="ECO:0000256|SAM:SignalP,
FT ECO:0000313|RefSeq:NP_001117083.1"
FT /id="PRO_5009732048"
FT TRANSMEM 435..459
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 111..207
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 216..339
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 354..425
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 490 AA; 54926 MW; C0C0FE233D670E9E CRC64;
MKYVSGFLSI IIALFISSTA AGDVLVYGQV GGTVTLPRSK WGSERVLVLW YLGTDTQPLI
SRNAHGRETI DPQWKDRLSL SKTDFSLIIN NIRLEDFKSF KCELKDFRPQ PTSVVTTFRL
SRVRVQPVSP LLAGKNLNLK CDIEEIVEGT QRRWLSPQKQ DPKNDTRVQI KNDGSLTVMS
VTGQDHGEWT CVVTYQGRKA NANTHVSVID LSPAHPQPIY TSVSSLSLLH LPCFLSNPPP
LSWSDSQEKS IQGGRWTFTP SPAAGSNTRV VQTLVNLSLG PPLAWVVNQK RGLDVSALQR
KNLNLSLTKK GVTEGDRGEY TCAVEFQKDD TLKRSIRVEV LQVFSSPAPV AFVGQEVNLT
CTLGQPLTSD LKVKWIPPRQ SSLLALGSSP HPAHLTIPEA RDINGGRWRC ELWRNKTKLT
SVEITLKIER VPMDVWLLVT ICAAAVIFIL LLILTVILIR RHRQRVMMPR RGKRRICRCK
DPKPKGFYRN
//
