ID B1AXS6_MOUSE Unreviewed; 1278 AA.
AC B1AXS6;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 92.
DE SubName: Full=Zinc finger, MYM-type 3 {ECO:0000313|Ensembl:ENSMUSP00000112497.2};
GN Name=Zmym3 {ECO:0000313|Ensembl:ENSMUSP00000112497.2,
GN ECO:0000313|MGI:MGI:1927231};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000112497.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000112497.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000112497.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0007829|PubMed:21183079}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
RN [3] {ECO:0000313|Ensembl:ENSMUSP00000112497.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000112497.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; NP_001171456.1; NM_001177985.1.
DR AlphaFoldDB; B1AXS6; -.
DR SMR; B1AXS6; -.
DR jPOST; B1AXS6; -.
DR MaxQB; B1AXS6; -.
DR ProteomicsDB; 367744; -.
DR Antibodypedia; 524; 196 antibodies from 24 providers.
DR DNASU; 56364; -.
DR Ensembl; ENSMUST00000117901.8; ENSMUSP00000112497.2; ENSMUSG00000031310.17.
DR GeneID; 56364; -.
DR UCSC; uc009txl.2; mouse.
DR AGR; MGI:1927231; -.
DR CTD; 9203; -.
DR MGI; MGI:1927231; Zmym3.
DR VEuPathDB; HostDB:ENSMUSG00000031310; -.
DR GeneTree; ENSGT00940000160693; -.
DR OrthoDB; 5399298at2759; -.
DR BioGRID-ORCS; 56364; 5 hits in 81 CRISPR screens.
DR Proteomes; UP000000589; Chromosome X.
DR Bgee; ENSMUSG00000031310; Expressed in embryonic brain and 253 other cell types or tissues.
DR ExpressionAtlas; B1AXS6; baseline and differential.
DR Genevisible; B1AXS6; MM.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR InterPro; IPR021893; DUF3504.
DR InterPro; IPR011017; TRASH_dom.
DR InterPro; IPR010507; Znf_MYM.
DR PANTHER; PTHR45736; ZINC FINGER MYM-TYPE PROTEIN; 1.
DR PANTHER; PTHR45736:SF3; ZINC FINGER MYM-TYPE PROTEIN 3; 1.
DR Pfam; PF12012; DUF3504; 1.
DR Pfam; PF06467; zf-FCS; 9.
DR SMART; SM00746; TRASH; 10.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:B1AXS6,
KW ECO:0007829|MaxQB:B1AXS6};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT DOMAIN 313..349
FT /note="TRASH"
FT /evidence="ECO:0000259|SMART:SM00746"
FT DOMAIN 355..395
FT /note="TRASH"
FT /evidence="ECO:0000259|SMART:SM00746"
FT DOMAIN 411..446
FT /note="TRASH"
FT /evidence="ECO:0000259|SMART:SM00746"
FT DOMAIN 453..494
FT /note="TRASH"
FT /evidence="ECO:0000259|SMART:SM00746"
FT DOMAIN 500..538
FT /note="TRASH"
FT /evidence="ECO:0000259|SMART:SM00746"
FT DOMAIN 548..584
FT /note="TRASH"
FT /evidence="ECO:0000259|SMART:SM00746"
FT DOMAIN 593..629
FT /note="TRASH"
FT /evidence="ECO:0000259|SMART:SM00746"
FT DOMAIN 635..670
FT /note="TRASH"
FT /evidence="ECO:0000259|SMART:SM00746"
FT DOMAIN 681..716
FT /note="TRASH"
FT /evidence="ECO:0000259|SMART:SM00746"
FT DOMAIN 722..757
FT /note="TRASH"
FT /evidence="ECO:0000259|SMART:SM00746"
FT REGION 1..73
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 85..310
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 761..831
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 120..134
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 161..176
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 198..214
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 229..254
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 261..277
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 293..307
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 761..801
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 813..829
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1278 AA; 142061 MW; 5CDC091BBA97D7D9 CRC64;
MDPSDFPSPF DPLTLPEKPL AGDLPVDMEF GEDLLESQTA PSRGWAPPGP SPSSGALDLL
DTPSGLEKDP GGVLDGATEL LGLGGLLYKA PSPPEVDHGP EGTLAWDSGE QTLEPGPGCQ
TPEVMPPDPG AGASPPSPEG LLEPLAPDSP IILESPHIEE EIPPLATRRR GSPGQEEEHT
QGQPQSPNAP PSPSVGETLG DGINSSQSKP GVCTPTAHPS LPGDGLTGKE IEKPPERVQK
RSERVRRAEP PKPEVVDSTE SIPVSDEDSD AMVDDPNDED FVPFRPRRSP RMSLRSSMAQ
RAGRSSMGTK MSCAHCRTPL QKGQTAYQRK GLPQLFCSSS CLTTYSKKPL GRKTCTFCKK
EIWNTKDSVV VQTGPGGSFH EFCTSVCLSL YEAQQQRPIP QSGDPADATR CSICQKTGEV
LHEVSNGSVV HRLCSDSCFS KFRANKGLKT NCCDQCGAYI YARPGGLGPE LLFHDGQQKR
FCNTTCLGAY KKKNTRVYPC VWCKTLCKNF EMLSHVDRNG KTSLFCSLCC TTSYKVKQAG
LTGPPRPCSF CRRSLSDPCY YNKVDRTVYQ FCSPSCWTKF QHTSPEGGIH LSCHYCHSLF
SGKPEVLEWQ DQVFQFCCRD CCEDFKRLRG VVSQCEHCRQ EKLLHEKLRF SGVEKSFCSE
GCVLLYKQDF TKKLGLCCIT CTYCSQTCQR GVTEQLDGST WDFCSEDCKT KYLLWYCKAA
RCHACKRQGK LLETIHWRGQ IRHFCNQQCL LRFYSQQNQP NLDTQSGPES LLNSQSSESK
PQTPSQTKVE NNHTVRTPDE NGNLGKTPVK RATPSVPTPP PPPPPATPRK NKAAMCKPLM
QNRGVSCKAE MKSKGSQTEE WKPQVIVLPI PVPIFVPVPM HLYCQKVPVP FSMPIPVPVP
MFLPTTLEST EKIVETIEEL KVKIPSNPLE ADILAMAEMI AEAEELDKAS SDLCDLVSNQ
SAEGLLEDCD LFGTARDDVL AMAVKMANVL DEPGQDLEAD FPKNPLDINP SVDFLFDCGL
VGPEDVSTEQ DLPRAMRKGQ KRLMLSESCS RDSLSSQPSC TGLNYSYGVN AWKCWVQSKY
ANGETSKAKP MRIKEDILAC SAAELNYGLA QFVREITRPN GERYEPDSIY YLCLGIQQYL
LENNRMVNIF TDLYYLTFVQ ELNKSLSTWQ PTLLPNNTGP GKRKREDETI LEQRENRMNP
LRCPVKFYEF YLSKCPESLR TRNDVFYLQP ERSCIAESPL WYSVIPMDRS MLESMLNRIL
AVREIYEELG RPGEEDLD
//
