ID B1H2X3_XENTR Unreviewed; 284 AA.
AC B1H2X3; F6TBF5;
DT 29-APR-2008, integrated into UniProtKB/TrEMBL.
DT 29-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE SubName: Full=Tpm1 protein {ECO:0000313|EMBL:AAI61164.1};
DE SubName: Full=Tropomyosin alpha-1 chain isoform X1 {ECO:0000313|RefSeq:XP_012821869.1};
GN Name=tpm1 {ECO:0000313|EMBL:AAI61164.1,
GN ECO:0000313|RefSeq:XP_012821869.1,
GN ECO:0000313|Xenbase:XB-GENE-485946};
GN Synonyms=alpha-tm {ECO:0000313|RefSeq:XP_012821869.1}, CH1
GN {ECO:0000313|RefSeq:XP_012821869.1}, htm-alpha
GN {ECO:0000313|RefSeq:XP_012821869.1}, tm3
GN {ECO:0000313|RefSeq:XP_012821869.1}, tmsa
GN {ECO:0000313|RefSeq:XP_012821869.1}, tpm1-alpha
GN {ECO:0000313|RefSeq:XP_012821869.1}, tpm1-kappa
GN {ECO:0000313|RefSeq:XP_012821869.1}, tpm3
GN {ECO:0000313|RefSeq:XP_012821869.1};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|EMBL:AAI61164.1};
RN [1] {ECO:0000313|EMBL:AAI61164.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=PopA {ECO:0000313|EMBL:AAI61164.1}, and TGA IC
RC {ECO:0000313|EMBL:AAI68590.1};
RC TISSUE=Limb {ECO:0000313|EMBL:AAI68590.1}, and Whole
RC {ECO:0000313|EMBL:AAI61164.1};
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|RefSeq:XP_012821869.1}
RP IDENTIFICATION.
RC STRAIN=Nigerian {ECO:0000313|RefSeq:XP_012821869.1};
RC TISSUE=Liver and blood {ECO:0000313|RefSeq:XP_012821869.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the tropomyosin family.
CC {ECO:0000256|ARBA:ARBA00009036, ECO:0000256|RuleBase:RU004515}.
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DR EMBL; BC161164; AAI61164.1; -; mRNA.
DR EMBL; BC168590; AAI68590.1; -; mRNA.
DR RefSeq; XP_012821869.1; XM_012966415.1.
DR PaxDb; 8364-ENSXETP00000021409; -.
DR DNASU; 448541; -.
DR GeneID; 448541; -.
DR AGR; Xenbase:XB-GENE-485946; -.
DR CTD; 7168; -.
DR Xenbase; XB-GENE-485946; tpm1.
DR eggNOG; KOG1003; Eukaryota.
DR HOGENOM; CLU_055027_0_0_1; -.
DR OrthoDB; 5398117at2759; -.
DR TreeFam; TF351519; -.
DR Proteomes; UP000008143; Chromosome 3.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR Gene3D; 1.20.5.170; -; 2.
DR Gene3D; 1.20.5.340; -; 1.
DR InterPro; IPR000533; Tropomyosin.
DR PANTHER; PTHR19269; TROPOMYOSIN; 1.
DR PANTHER; PTHR19269:SF38; TROPOMYOSIN ALPHA-3 CHAIN; 1.
DR Pfam; PF00261; Tropomyosin; 1.
DR PRINTS; PR00194; TROPOMYOSIN.
DR SUPFAM; SSF57997; Tropomyosin; 1.
DR PROSITE; PS00326; TROPOMYOSIN; 1.
PE 2: Evidence at transcript level;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Muscle protein {ECO:0000256|ARBA:ARBA00023179};
KW Reference proteome {ECO:0000313|Proteomes:UP000008143}.
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 284 AA; 32661 MW; DCFBD6A31050C490 CRC64;
MDAIKKKMQM LKLDKENALD RAEQAEADKK GAEEKSKQLE DELVALQKKL KGTEDELDKY
SEALKDAQEK LELAEKKATD AEGDVASLNR RIQLVEEELD RAQERLATAL QKLEEAEKAA
DESERGMKVI ENRALKDEEK MELQEIQLKE AKHIAEEADR KYEEVARKLV IIEGDLERAE
ERAELSESKC AELEEELKTV TNNLKSLEAQ AEKYSQKEDK YEEEIKVLTD KLKEAETRAE
FAERTVAKLE KTIDDLEDEL YAQKLKYKAI SEELDHALND MTSI
//
