GenomeNet

Database: UniProt
Entry: B1JHZ0
LinkDB: B1JHZ0
Original site: B1JHZ0 
ID   MALT_YERPY              Reviewed;         903 AA.
AC   B1JHZ0;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   29-APR-2008, sequence version 1.
DT   08-MAY-2019, entry version 75.
DE   RecName: Full=HTH-type transcriptional regulator MalT {ECO:0000255|HAMAP-Rule:MF_01247};
DE   AltName: Full=ATP-dependent transcriptional activator MalT {ECO:0000255|HAMAP-Rule:MF_01247};
GN   Name=malT {ECO:0000255|HAMAP-Rule:MF_01247};
GN   OrderedLocusNames=YPK_0160;
OS   Yersinia pseudotuberculosis serotype O:3 (strain YPIII).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=502800;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YPIII;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Bruce D., Goodwin L., Pitluck S., Munk A.C., Brettin T.,
RA   Detter J.C., Han C., Tapia R., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Challacombe J.F., Green L., Lindler L.E., Nikolich M.P.,
RA   Richardson P.;
RT   "Complete sequence of Yersinia pseudotuberculosis YPIII.";
RL   Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Positively regulates the transcription of the maltose
CC       regulon whose gene products are responsible for uptake and
CC       catabolism of malto-oligosaccharides. Specifically binds to the
CC       promoter region of its target genes, recognizing a short DNA motif
CC       called the MalT box. {ECO:0000255|HAMAP-Rule:MF_01247}.
CC   -!- ACTIVITY REGULATION: Activated by ATP and maltotriose, which are
CC       both required for DNA binding. {ECO:0000255|HAMAP-Rule:MF_01247}.
CC   -!- SUBUNIT: Monomer in solution. Oligomerizes to an active state in
CC       the presence of the positive effectors ATP and maltotriose.
CC       {ECO:0000255|HAMAP-Rule:MF_01247}.
CC   -!- SIMILARITY: Belongs to the MalT family. {ECO:0000255|HAMAP-
CC       Rule:MF_01247}.
DR   EMBL; CP000950; ACA66473.1; -; Genomic_DNA.
DR   RefSeq; WP_002208926.1; NZ_CP009792.1.
DR   SMR; B1JHZ0; -.
DR   EnsemblBacteria; ACA66473; ACA66473; YPK_0160.
DR   KEGG; ypy:YPK_0160; -.
DR   PATRIC; fig|502800.11.peg.767; -.
DR   HOGENOM; HOG000218261; -.
DR   KO; K03556; -.
DR   OMA; SDWVSNA; -.
DR   BioCyc; YPSE502800:G1GBB-162-MONOMER; -.
DR   Proteomes; UP000000721; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0045913; P:positive regulation of carbohydrate metabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   CDD; cd06170; LuxR_C_like; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 1.25.40.10; -; 1.
DR   HAMAP; MF_01247; HTH_type_MalT; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR041617; TPR_MalT.
DR   InterPro; IPR023768; Tscrpt_reg_HTH_MalT.
DR   InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   Pfam; PF00196; GerE; 1.
DR   Pfam; PF17874; TPR_MalT; 1.
DR   PRINTS; PR00038; HTHLUXR.
DR   SMART; SM00421; HTH_LUXR; 1.
DR   SUPFAM; SSF46894; SSF46894; 1.
DR   SUPFAM; SSF48452; SSF48452; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00622; HTH_LUXR_1; 1.
DR   PROSITE; PS50043; HTH_LUXR_2; 1.
PE   3: Inferred from homology;
KW   Activator; ATP-binding; Carbohydrate metabolism; Complete proteome;
KW   DNA-binding; Nucleotide-binding; Transcription;
KW   Transcription regulation.
FT   CHAIN         1    903       HTH-type transcriptional regulator MalT.
FT                                /FTId=PRO_1000139862.
FT   DOMAIN      832    897       HTH luxR-type. {ECO:0000255|HAMAP-
FT                                Rule:MF_01247}.
FT   NP_BIND      39     46       ATP. {ECO:0000255|HAMAP-Rule:MF_01247}.
FT   DNA_BIND    856    875       H-T-H motif. {ECO:0000255|HAMAP-
FT                                Rule:MF_01247}.
SQ   SEQUENCE   903 AA;  103165 MW;  728A538719E42251 CRC64;
     MLIPSKLSRP VRLQNTVVRD RLLVKLSSAA NYRLTLINCP AGYGKTTLIA QWAADQSNLG
     WYSLDESDNQ SERFATYLIA AIQLATGGHC SKSEALSQKH QYANLSALFS QLFIELSNWD
     GPLYLVIDDY HLITNDAIHE AMRFFLRHQP ENLTLIILSR TLPSLGIANL RVRDQLLELG
     MQQLAFNHHE AQQFFECRLS SPLEQGDSSR LCDEVEGWVT ALQLIALSSR QPNSSAQKSA
     KRLAGLNASH LSDYLVDEVL DQVDSKARAF LLRCSVLRSM NDALIVRLTG EDNGQQLLEE
     LERQGLFIHR MDDSAEWFCF HPLFATFLRQ RCQWELALEL PELHHAAAEG WMALGYPAEA
     IHHALAAGDV GMLRDILLQH AWSLFHHSEL ALLEQCLTAL PYPLLVQNPE LALLQAWLAQ
     SQHRYSEVNT LLEQAELAMQ ERKIPVDEIL RAEFGALRAQ VAINAGKPDE AEKLATDALK
     YLPMAHYYSR IVATSVTGEV HHCKGELARA LPMMQQTEQM ARRHEAYHYA LWALLQQSEI
     LIAQGFLQAA YETQEKAFEL IREQHLEQLP MHEFLLRIRS QVLWSWSRLD EAEEAARKGV
     EILANYQPQQ QLQCLAMLAK CSLARGDLDN ANVYIQRCEA LQHGSQYHLD WITNADKPRV
     IHWQMTGDKV AAASWLRQTE KPGMADNHFL QGQWRNIARV QIILGRFDEA EVVLDELNEN
     ARRLRLTSDL NRNLLLSNTL YWQTERKGEA QKALIESLTL ANRTGFISHF VIEGEAMAQQ
     LRQLIQLNAL PELEQHRAQR ILKDINQHHR HKFAHFDEIF VDKLLTHPQV PELIRTSPLT
     QREWQVLGLI YSGYSNDQIA NELDVAATTI KTHIRNLYQK LGVAHRQEAV QQAQRLLQMM
     GYV
//
DBGET integrated database retrieval system