ID B1MWB2_LEUCK Unreviewed; 445 AA.
AC B1MWB2;
DT 29-APR-2008, integrated into UniProtKB/TrEMBL.
DT 29-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Gamma-aminobutyrate permease {ECO:0000313|EMBL:ACA83477.1};
GN Name=aapA {ECO:0000313|EMBL:ACA83477.1};
GN OrderedLocusNames=LCK_01654 {ECO:0000313|EMBL:ACA83477.1};
OS Leuconostoc citreum (strain KM20).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Leuconostoc.
OX NCBI_TaxID=349519 {ECO:0000313|EMBL:ACA83477.1, ECO:0000313|Proteomes:UP000002166};
RN [1] {ECO:0000313|EMBL:ACA83477.1, ECO:0000313|Proteomes:UP000002166}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KM20 {ECO:0000313|EMBL:ACA83477.1,
RC ECO:0000313|Proteomes:UP000002166};
RX PubMed=18281406; DOI=10.1128/JB.01862-07;
RA Kim J.F., Jeong H., Lee J.-S., Choi S.-H., Ha M., Hur C.-G., Kim J.-S.,
RA Lee S., Park H.-S., Park Y.-H., Oh T.K.;
RT "Complete genome sequence of Leuconostoc citreum KM20.";
RL J. Bacteriol. 190:3093-3094(2008).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; DQ489736; ACA83477.1; -; Genomic_DNA.
DR RefSeq; WP_004908857.1; NC_010471.1.
DR AlphaFoldDB; B1MWB2; -.
DR KEGG; lci:LCK_01654; -.
DR eggNOG; COG1113; Bacteria.
DR HOGENOM; CLU_007946_9_3_9; -.
DR OrthoDB; 9780162at2; -.
DR Proteomes; UP000002166; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR004841; AA-permease/SLC12A_dom.
DR PANTHER; PTHR43495:SF2; D-SERINE_D-ALANINE_GLYCINE TRANSPORTER; 1.
DR PANTHER; PTHR43495; GABA PERMEASE; 1.
DR Pfam; PF00324; AA_permease; 1.
DR PIRSF; PIRSF006060; AA_transporter; 1.
PE 4: Predicted;
KW Amino-acid transport {ECO:0000256|ARBA:ARBA00022970};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 16..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 45..67
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 88..111
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 123..141
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 153..175
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 200..221
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 242..260
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 280..304
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 325..347
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 353..374
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 395..416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 422..440
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 15..438
FT /note="Amino acid permease/ SLC12A"
FT /evidence="ECO:0000259|Pfam:PF00324"
SQ SEQUENCE 445 AA; 49150 MW; CA8FA7A7304892AB CRC64;
MQQEHKLART LSGRHINMIA LGGTIGTGLF LGAGDSIQKA GPAIVLVYII TGLFVFAMMR
ALGELLLSDH DQTTFIGFIK SYLGPRAGFV MGWTYWIGWI IIAMAELTAI GKYMQFWLPT
TPAWLWELIF LGLLYTMNII AVKAFGETEF WFALIKIVAI IAMIVIGIVM VVFHVRTSAG
VTQLSTLWSH GLIANHGHNL LAAFQMAFFA FLGVEFVGIA ASETQNPIQT IPRSINAIIM
RILIFYVGAL LAIMVIQPWT NYSANQSPFV QVFSKIGIPA AAGIINFVIL TAAASSLNSA
LFTTGRMIFS LSPKTSRFAK LNKHYIPMNG ITLSSGLVAT AIVLNYIFPK DAFSLVTSTA
SATFIVIYIA LMVTHVKYRQ SKNYQQSDKH FKMPFAPYLN YLTILFMLMI FGILLFSSAT
MITTLLAISW FIVLAVISVV KYKKV
//
