ID B1T6A4_9BURK Unreviewed; 436 AA.
AC B1T6A4;
DT 20-MAY-2008, integrated into UniProtKB/TrEMBL.
DT 20-MAY-2008, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Cobalamin synthesis protein P47K {ECO:0000313|EMBL:EDT40903.1};
GN ORFNames=BamMEX5DRAFT_3320 {ECO:0000313|EMBL:EDT40903.1};
OS Burkholderia ambifaria MEX-5.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX NCBI_TaxID=396597 {ECO:0000313|EMBL:EDT40903.1, ECO:0000313|Proteomes:UP000004814};
RN [1] {ECO:0000313|EMBL:EDT40903.1, ECO:0000313|Proteomes:UP000004814}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MEX-5 {ECO:0000313|EMBL:EDT40903.1,
RC ECO:0000313|Proteomes:UP000004814};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Larimer F., Land M.L., Hauser L.,
RA Tiedje J., Richardson P.;
RT "Sequencing of the draft genome and assembly of Burkholderia ambifaria MEX-
RT 5.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDT40903.1}.
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DR EMBL; ABLK01000101; EDT40903.1; -; Genomic_DNA.
DR RefSeq; WP_006759200.1; NZ_ABLK01000101.1.
DR AlphaFoldDB; B1T6A4; -.
DR PATRIC; fig|396597.7.peg.4670; -.
DR Proteomes; UP000004814; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR43603; COBW DOMAIN-CONTAINING PROTEIN DDB_G0274527; 1.
DR PANTHER; PTHR43603:SF1; COBW DOMAIN-CONTAINING PROTEIN DDB_G0274527; 1.
DR Pfam; PF02492; cobW; 1.
DR Pfam; PF07683; CobW_C; 1.
DR SMART; SM00833; CobW_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 276..396
FT /note="CobW C-terminal"
FT /evidence="ECO:0000259|SMART:SM00833"
SQ SEQUENCE 436 AA; 47895 MW; FD38D39C5E18B486 CRC64;
MNPAMNQPLP VTVLSGFLGA GKTTLLNHIL ANRAGLKVAV IVNDLAAVNI DASLVRDAQA
LSHVEERLVE MSNGCICCTL RDDLLVEIRN LAADGRFDAI VIESTGIAEP MPIAETFTFV
DDDGTSLSNV ARLDTLVTVV DAYNFLRDYG SDDALATRGI AASDEDDRTL VELLIEQIEF
CDVLVINKAD LVGADELARL RHILARLNPR AHQVVSTFGN VPLDEVLNTG RFDFDEAANA
PGWLASLEDD HTHCDDPECH DPHHAHVHGE ADEFGIGNFV YRARRPFHPA RLWALLHQEW
PGVLRSKGFF WLATRNDIAG SLSQAGGVCR HGPAGLWWAA QDRAEWPDDD ELLAEIRTEW
QGDLDDRSVG DRRQELVLIG IGLDADAWRA KLDACLLTDA EFALGAAQWT AFDDPFPAWD
VDAHDDEDPD AQIVHA
//
