ID B1WQ10_CROS5 Unreviewed; 486 AA.
AC B1WQ10;
DT 20-MAY-2008, integrated into UniProtKB/TrEMBL.
DT 20-MAY-2008, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Probable retinal pigment epithelial membrane protein {ECO:0000313|EMBL:ACB53325.1};
GN OrderedLocusNames=cce_3977 {ECO:0000313|EMBL:ACB53325.1};
OS Crocosphaera subtropica (strain ATCC 51142 / BH68) (Cyanothece sp. (strain
OS ATCC 51142)).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Chroococcales; Aphanothecaceae; Crocosphaera; Crocosphaera subtropica.
OX NCBI_TaxID=43989 {ECO:0000313|EMBL:ACB53325.1, ECO:0000313|Proteomes:UP000001203};
RN [1] {ECO:0000313|EMBL:ACB53325.1, ECO:0000313|Proteomes:UP000001203}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51142 / BH68 {ECO:0000313|Proteomes:UP000001203};
RX PubMed=18812508; DOI=10.1073/pnas.0805418105;
RA Welsh E.A., Liberton M., Stoeckel J., Loh T., Elvitigala T., Wang C.,
RA Wollam A., Fulton R.S., Clifton S.W., Jacobs J.M., Aurora R., Ghosh B.K.,
RA Sherman L.A., Smith R.D., Wilson R.K., Pakrasi H.B.;
RT "The genome of Cyanothece 51142, a unicellular diazotrophic cyanobacterium
RT important in the marine nitrogen cycle.";
RL Proc. Natl. Acad. Sci. U.S.A. 105:15094-15099(2008).
CC -!- COFACTOR:
CC Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC Evidence={ECO:0000256|PIRSR:PIRSR604294-1};
CC Note=Binds 1 Fe(2+) ion per subunit. {ECO:0000256|PIRSR:PIRSR604294-1};
CC -!- SIMILARITY: Belongs to the carotenoid oxygenase family.
CC {ECO:0000256|ARBA:ARBA00006787}.
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DR EMBL; CP000806; ACB53325.1; -; Genomic_DNA.
DR RefSeq; WP_009543931.1; NC_010546.1.
DR AlphaFoldDB; B1WQ10; -.
DR STRING; 43989.cce_3977; -.
DR KEGG; cyt:cce_3977; -.
DR eggNOG; COG3670; Bacteria.
DR HOGENOM; CLU_016472_0_2_3; -.
DR OrthoDB; 6636843at2; -.
DR Proteomes; UP000001203; Chromosome circular.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:InterPro.
DR InterPro; IPR004294; Carotenoid_Oase.
DR PANTHER; PTHR10543; BETA-CAROTENE DIOXYGENASE; 1.
DR PANTHER; PTHR10543:SF89; CAROTENOID 9,10(9',10')-CLEAVAGE DIOXYGENASE 1; 1.
DR Pfam; PF03055; RPE65; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|PIRSR:PIRSR604294-1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|PIRSR:PIRSR604294-1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000001203}.
FT BINDING 188
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 237
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 301
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 480
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
SQ SEQUENCE 486 AA; 56505 MW; 5222FD6F7DEA5DB0 CRC64;
MKRRQFLIQS SLAAMTAIAY HQLPSQSSPI YKQYKSYKSW KSDNIFLRGM NAPVFEEVDI
SNLKISGKIP TKLQGMYVRN GPNPMFKPES YSYPIEGDGM LHGIYFSNGE VSYKNRWIQT
RGLTYEMFEG KQLKELKFKN YANTNIIAHG NKLLALYETG LPYEVNKNLE TIGEWDFNHQ
LEQAMTAHPK IDPKTGELHF YRYSFFNTPY LHYYVADSNN KIIRELPIEI PQPTMIHDMA
ITENYIIFFN CPLVFNMTEA KNNNIPFVWQ EEQGTTIILV DRHNLDKKPI YLKTDAFWTW
HFMNSFEAND RLFIDFVAYP KIQSENNWET MLTQKSNLRR LTINLETHTM DFQDLDDRFV
ELPVIHQNYV GTAYQFGYTS YYDTQLSSQK KIPNLSPSLI QYDVVKNNHK IHQFKPGCYG
GEAAFIPSSN GQSELDGYVV TFVYNENTNT SDFIIIDPHN FASEPIATVH LPVRVPSGFH
GNWISS
//
