ID B1WUW3_CROS5 Unreviewed; 743 AA.
AC B1WUW3;
DT 20-MAY-2008, integrated into UniProtKB/TrEMBL.
DT 20-MAY-2008, sequence version 1.
DT 27-MAR-2024, entry version 91.
DE SubName: Full=Nitrate reductase {ECO:0000313|EMBL:ACB50564.1};
GN Name=narB {ECO:0000313|EMBL:ACB50564.1};
GN OrderedLocusNames=cce_1214 {ECO:0000313|EMBL:ACB50564.1};
OS Crocosphaera subtropica (strain ATCC 51142 / BH68) (Cyanothece sp. (strain
OS ATCC 51142)).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Chroococcales; Aphanothecaceae; Crocosphaera; Crocosphaera subtropica.
OX NCBI_TaxID=43989 {ECO:0000313|EMBL:ACB50564.1, ECO:0000313|Proteomes:UP000001203};
RN [1] {ECO:0000313|EMBL:ACB50564.1, ECO:0000313|Proteomes:UP000001203}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51142 / BH68 {ECO:0000313|Proteomes:UP000001203};
RX PubMed=18812508; DOI=10.1073/pnas.0805418105;
RA Welsh E.A., Liberton M., Stoeckel J., Loh T., Elvitigala T., Wang C.,
RA Wollam A., Fulton R.S., Clifton S.W., Jacobs J.M., Aurora R., Ghosh B.K.,
RA Sherman L.A., Smith R.D., Wilson R.K., Pakrasi H.B.;
RT "The genome of Cyanothece 51142, a unicellular diazotrophic cyanobacterium
RT important in the marine nitrogen cycle.";
RL Proc. Natl. Acad. Sci. U.S.A. 105:15094-15099(2008).
CC -!- COFACTOR:
CC Name=Mo-bis(molybdopterin guanine dinucleotide);
CC Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- PATHWAY: Nitrogen metabolism. {ECO:0000256|ARBA:ARBA00004909}.
CC -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC oxidoreductase family. NasA/NapA/NarB subfamily.
CC {ECO:0000256|ARBA:ARBA00008747}.
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DR EMBL; CP000806; ACB50564.1; -; Genomic_DNA.
DR RefSeq; WP_009544043.1; NC_010546.1.
DR AlphaFoldDB; B1WUW3; -.
DR STRING; 43989.cce_1214; -.
DR KEGG; cyt:cce_1214; -.
DR eggNOG; COG0243; Bacteria.
DR HOGENOM; CLU_000422_13_4_3; -.
DR OrthoDB; 9803192at2; -.
DR Proteomes; UP000001203; Chromosome circular.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.
DR CDD; cd02791; MopB_CT_Nitrate-R-NapA-like; 1.
DR CDD; cd02754; MopB_Nitrate-R-NapA-like; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 2.20.25.90; ADC-like domains; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR041957; CT_Nitrate-R-NapA-like.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR InterPro; IPR027467; MopterinOxRdtase_cofactor_BS.
DR PANTHER; PTHR43105:SF9; NITRATE REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G15190)-RELATED; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR Pfam; PF04879; Molybdop_Fe4S4; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR SMART; SM00926; Molybdop_Fe4S4; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
DR PROSITE; PS00551; MOLYBDOPTERIN_PROK_1; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Molybdenum {ECO:0000256|ARBA:ARBA00022505};
KW Nitrate assimilation {ECO:0000256|ARBA:ARBA00023063};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000001203}.
FT DOMAIN 2..70
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
SQ SEQUENCE 743 AA; 83315 MW; 10B9274BB56D6BF5 CRC64;
MTNSTKTLCP YCGVGCGLEV LPPAQPGKPV NRDSEGTPIW QVRGDRNHPS SLGKVCVKGA
TVSESLEKSR LKYPMMRDSL TDEFRRVSWD EAMEAIVNRM QTLRLTQGPD ALCMYGSGQF
QTEDYYIAQK LFKGFLGTNN FDANSRLCMS SAVAGYTQSF GSDGPPCCYE DLELTDCAFL
IGTNTAECHP IVFNRLRVHH KKNRKVKMVV VDPRRTQTAE AADLHLAIKP GTDIDLFNGI
AYLLMRWGRI DTFFIDECTQ NFSAYADVIR HYPPELVARN CGIRIDELEK AAQYWGDSER
VLSLWSMGIN QSSEGTAKVR TLINLHLMTG DIGKPGAGPF SLTGQPNAMG GREAGGLCNI
LPGYRVINNP QHRAEVEQFW KLPQGSIQPQ RGRTAWEMIQ GLETGEVGFL WIAATNPAVS
MPDIKRTQAA LKRSPFTVYQ DAYYPTETSA YAHILLPAAQ WSEKTGVMTN SERMVTLCPQ
FRDPPGEARP DWEVFAEVGR RLGFTEGFNF KTSAEVYAEF VQITEGRPCD SSGLSHDKLR
TYGPLQWPYP DAWPWLEGED LEQQNRTNKR LYTDFRFNTP DGRARFAAYH SKGLAEPTDE
AYPFVLTTGR LYGHWHTQTR TGRIPKIQKM HPDPFMEIHP QDAAKLNIEE NTFVEVRSRR
GKARFLAKIT KAIAPGTLFI PMHWGALWAE DAEANALTHP NACPTSLQPE LKACAVQVKV
ATEEEWVITS SESEVQSSEL RVI
//
