ID B1Y0Z5_LEPCP Unreviewed; 303 AA.
AC B1Y0Z5;
DT 20-MAY-2008, integrated into UniProtKB/TrEMBL.
DT 20-MAY-2008, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Methylenetetrahydrofolate dehydrogenase (NADP(+)) {ECO:0000313|EMBL:ACB35412.1};
DE EC=1.5.1.5 {ECO:0000313|EMBL:ACB35412.1};
DE Flags: Precursor;
GN OrderedLocusNames=Lcho_3152 {ECO:0000313|EMBL:ACB35412.1};
OS Leptothrix cholodnii (strain ATCC 51168 / LMG 8142 / SP-6) (Leptothrix
OS discophora (strain SP-6)).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Sphaerotilaceae; Leptothrix.
OX NCBI_TaxID=395495 {ECO:0000313|EMBL:ACB35412.1, ECO:0000313|Proteomes:UP000001693};
RN [1] {ECO:0000313|EMBL:ACB35412.1, ECO:0000313|Proteomes:UP000001693}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51168 / LMG 8142 / SP-6
RC {ECO:0000313|Proteomes:UP000001693};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C.,
RA Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L.,
RA Kyrpides N., Lykidis A., Emerson D., Richardson P.;
RT "Complete sequence of Leptothrix cholodnii SP-6.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP001013; ACB35412.1; -; Genomic_DNA.
DR RefSeq; WP_012348161.1; NC_010524.1.
DR AlphaFoldDB; B1Y0Z5; -.
DR STRING; 395495.Lcho_3152; -.
DR KEGG; lch:Lcho_3152; -.
DR eggNOG; COG1748; Bacteria.
DR HOGENOM; CLU_059363_0_0_4; -.
DR OrthoDB; 8556544at2; -.
DR Proteomes; UP000001693; Chromosome.
DR GO; GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.50.10280; Methylene-tetrahydromethanopterin dehydrogenase, N-terminal domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR046346; Aminoacid_DH-like_N_sf.
DR InterPro; IPR015259; Methyl-teptahyd_DH_N.
DR InterPro; IPR037089; Methyl-teptahyd_DH_N_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR Pfam; PF09176; Mpt_N; 1.
DR SUPFAM; SSF53223; Aminoacid dehydrogenase-like, N-terminal domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:ACB35412.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001693}.
FT DOMAIN 18..98
FT /note="Methylene-tetrahydromethanopterin dehydrogenase N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF09176"
SQ SEQUENCE 303 AA; 30693 MW; C8AB80757ED22FCF CRC64;
MERPYILHMF TPGSQMSPFD INMAADAGWQ VITPYCNVAL SAIGALTQDT IFSRSPKGLA
RTGIFIGGRD ALLAADMLEA ARKAMFKPFQ VSLMADPSGA YTTAAAMVAS VEAALLAQAG
AGFAGRRVVV LGGTGPVGRI AAVLAAQAGA QVAISSRNGI DAADEAAQQT ALRFGVALEG
VSGGDRAAMR ASIAEVDVIL ACAAAGVQVV SADEVAQAGA LRVVADVNAV PPAGVAGVDV
MASRAPIAGT QALGIGALAI GNVKYQTQQL LLRRMHEAGT PQVLGFAEAF EVARQHLAQP
AAA
//
