ID B1YGR9_EXIS2 Unreviewed; 151 AA.
AC B1YGR9;
DT 20-MAY-2008, integrated into UniProtKB/TrEMBL.
DT 20-MAY-2008, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE RecName: Full=Transcriptional regulator CtsR {ECO:0000256|ARBA:ARBA00014129, ECO:0000256|PIRNR:PIRNR010607};
GN OrderedLocusNames=Exig_0065 {ECO:0000313|EMBL:ACB59552.1};
OS Exiguobacterium sibiricum (strain DSM 17290 / CIP 109462 / JCM 13490 /
OS 255-15).
OC Bacteria; Bacillota; Bacilli; Bacillales;
OC Bacillales Family XII. Incertae Sedis; Exiguobacterium.
OX NCBI_TaxID=262543 {ECO:0000313|EMBL:ACB59552.1, ECO:0000313|Proteomes:UP000001681};
RN [1] {ECO:0000313|EMBL:ACB59552.1, ECO:0000313|Proteomes:UP000001681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17290 / CIP 109462 / JCM 13490 / 255-15
RC {ECO:0000313|Proteomes:UP000001681};
RX PubMed=16489412; DOI=10.1007/s00792-005-0497-5;
RA Rodrigues D.F., Goris J., Vishnivetskaya T., Gilichinsky D.,
RA Thomashow M.F., Tiedje J.M.;
RT "Characterization of Exiguobacterium isolates from the Siberian permafrost.
RT Description of Exiguobacterium sibiricum sp. nov.";
RL Extremophiles 10:285-294(2006).
RN [2] {ECO:0000313|EMBL:ACB59552.1, ECO:0000313|Proteomes:UP000001681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17290 / CIP 109462 / JCM 13490 / 255-15
RC {ECO:0000313|Proteomes:UP000001681};
RX PubMed=19019206; DOI=10.1186/1471-2164-9-547;
RA Rodrigues D.F., Ivanova N., He Z., Huebner M., Zhou J., Tiedje J.M.;
RT "Architecture of thermal adaptation in an Exiguobacterium sibiricum strain
RT isolated from 3 million year old permafrost: a genome and transcriptome
RT approach.";
RL BMC Genomics 9:547-547(2008).
RN [3] {ECO:0000313|Proteomes:UP000001681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17290 / CIP 109462 / JCM 13490 / 255-15
RC {ECO:0000313|Proteomes:UP000001681};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kiss H., Chertkov O., Monk C.,
RA Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F.,
RA Land M., Hauser L., Kyrpides N., Mikhailova N., Vishnivetskaya T.,
RA Rodrigues D.F., Gilichinsky D., Tiedje J., Richardson P.;
RT "Complete sequence of chromosome of Exiguobacterium sibiricum 255-15.";
RL Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the CtsR family. {ECO:0000256|ARBA:ARBA00010189,
CC ECO:0000256|PIRNR:PIRNR010607}.
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DR EMBL; CP001022; ACB59552.1; -; Genomic_DNA.
DR RefSeq; WP_012368978.1; NC_010556.1.
DR AlphaFoldDB; B1YGR9; -.
DR STRING; 262543.Exig_0065; -.
DR KEGG; esi:Exig_0065; -.
DR eggNOG; COG4463; Bacteria.
DR HOGENOM; CLU_118139_0_0_9; -.
DR OrthoDB; 1680813at2; -.
DR Proteomes; UP000001681; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.1200.150; Transcriptional regulator CtsR, C-terminal domain; 1.
DR Gene3D; 3.30.56.130; Transcriptional regulator CtsR, winged HTH domain; 1.
DR InterPro; IPR008463; CtsR.
DR InterPro; IPR041473; CtsR_C.
DR InterPro; IPR041908; CtsR_C_sf.
DR InterPro; IPR040465; CtsR_N.
DR InterPro; IPR041902; CtsR_N_sf.
DR Pfam; PF05848; CtsR; 1.
DR Pfam; PF17727; CtsR_C; 1.
DR PIRSF; PIRSF010607; Txn_repr_CtsR; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PIRNR:PIRNR010607};
KW Reference proteome {ECO:0000313|Proteomes:UP000001681};
KW Repressor {ECO:0000256|ARBA:ARBA00022491, ECO:0000256|PIRNR:PIRNR010607};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|PIRNR:PIRNR010607};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|PIRNR:PIRNR010607}.
FT DOMAIN 3..71
FT /note="CtsR N-terminal HTH"
FT /evidence="ECO:0000259|Pfam:PF05848"
FT DOMAIN 75..146
FT /note="CtsR C-terminal dimerization"
FT /evidence="ECO:0000259|Pfam:PF17727"
SQ SEQUENCE 151 AA; 17782 MW; 8C42A1DF113E9280 CRC64;
MQNITDIIEA YLKQILHDEK KIEIKRQEIA ERFDCVPSQI NYVINTRFTI EKGYFVESKR
GGGGYIRIQK IVILDSHDLL DEISRWVGND LTEQAAEDYL VRLINEQLLT RREAILIQSL
LQKESLPMAL EDQRRMRAHL MQTVLQTIKR L
//