ID B1YGY1_EXIS2 Unreviewed; 876 AA.
AC B1YGY1;
DT 20-MAY-2008, integrated into UniProtKB/TrEMBL.
DT 20-MAY-2008, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE SubName: Full=Non-specific serine/threonine protein kinase {ECO:0000313|EMBL:ACB61042.1};
DE EC=2.7.11.1 {ECO:0000313|EMBL:ACB61042.1};
GN OrderedLocusNames=Exig_1586 {ECO:0000313|EMBL:ACB61042.1};
OS Exiguobacterium sibiricum (strain DSM 17290 / CIP 109462 / JCM 13490 /
OS 255-15).
OC Bacteria; Bacillota; Bacilli; Bacillales;
OC Bacillales Family XII. Incertae Sedis; Exiguobacterium.
OX NCBI_TaxID=262543 {ECO:0000313|EMBL:ACB61042.1, ECO:0000313|Proteomes:UP000001681};
RN [1] {ECO:0000313|EMBL:ACB61042.1, ECO:0000313|Proteomes:UP000001681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17290 / CIP 109462 / JCM 13490 / 255-15
RC {ECO:0000313|Proteomes:UP000001681};
RX PubMed=16489412; DOI=10.1007/s00792-005-0497-5;
RA Rodrigues D.F., Goris J., Vishnivetskaya T., Gilichinsky D.,
RA Thomashow M.F., Tiedje J.M.;
RT "Characterization of Exiguobacterium isolates from the Siberian permafrost.
RT Description of Exiguobacterium sibiricum sp. nov.";
RL Extremophiles 10:285-294(2006).
RN [2] {ECO:0000313|EMBL:ACB61042.1, ECO:0000313|Proteomes:UP000001681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17290 / CIP 109462 / JCM 13490 / 255-15
RC {ECO:0000313|Proteomes:UP000001681};
RX PubMed=19019206; DOI=10.1186/1471-2164-9-547;
RA Rodrigues D.F., Ivanova N., He Z., Huebner M., Zhou J., Tiedje J.M.;
RT "Architecture of thermal adaptation in an Exiguobacterium sibiricum strain
RT isolated from 3 million year old permafrost: a genome and transcriptome
RT approach.";
RL BMC Genomics 9:547-547(2008).
RN [3] {ECO:0000313|Proteomes:UP000001681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17290 / CIP 109462 / JCM 13490 / 255-15
RC {ECO:0000313|Proteomes:UP000001681};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kiss H., Chertkov O., Monk C.,
RA Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F.,
RA Land M., Hauser L., Kyrpides N., Mikhailova N., Vishnivetskaya T.,
RA Rodrigues D.F., Gilichinsky D., Tiedje J., Richardson P.;
RT "Complete sequence of chromosome of Exiguobacterium sibiricum 255-15.";
RL Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP001022; ACB61042.1; -; Genomic_DNA.
DR RefSeq; WP_012370462.1; NC_010556.1.
DR AlphaFoldDB; B1YGY1; -.
DR STRING; 262543.Exig_1586; -.
DR KEGG; esi:Exig_1586; -.
DR eggNOG; COG0553; Bacteria.
DR eggNOG; COG4715; Bacteria.
DR HOGENOM; CLU_000315_21_7_9; -.
DR OrthoDB; 9760715at2; -.
DR Proteomes; UP000001681; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR013663; Helicase_SWF/SNF/SWI_bac.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR InterPro; IPR007527; Znf_SWIM.
DR PANTHER; PTHR10799:SF1020; BTAF (TBP-ASSOCIATED FACTOR) HOMOLOG; 1.
DR PANTHER; PTHR10799; SNF2/RAD54 HELICASE FAMILY; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR Pfam; PF08455; SNF2_assoc; 1.
DR Pfam; PF04434; SWIM; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50966; ZF_SWIM; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Kinase {ECO:0000313|EMBL:ACB61042.1};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00325};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000001681};
KW Serine/threonine-protein kinase {ECO:0000313|EMBL:ACB61042.1};
KW Transferase {ECO:0000313|EMBL:ACB61042.1};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00325};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00325}.
FT DOMAIN 53..91
FT /note="SWIM-type"
FT /evidence="ECO:0000259|PROSITE:PS50966"
FT DOMAIN 436..593
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 702..862
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 876 AA; 99603 MW; 7074EEBDF26F9D2A CRC64;
MNYGLSERKI KQMSDTYAFR RGKRYVAAKK VTLRNYQSGD LLVEAAVQGE DLFTVTVRVK
EHGVDAGCNC PSLAMDQSFC GHIVAVLLAM HHVQVYGTPG GNQSLIRPFA TTRQTEDAAV
TAYLQTLSKA ERAKIRFDVN GSAIVMESIT AQQRFIISPM YFDRLLQRRD HLRNLADVWL
SPPLKQRLVS GPPTVELALD REAGGLELLV TFSYQGVRIN PLQETNWLGR DVSLEGAVLR
YVTESGFLER NGRYRLEEEA AEYQFLKGLL DPRVVYGELV VQVTESIRQS LPNGPFHPRI
DVDTTDRLDW LTFRFSMDGI PEVELKQVLQ SLVTRKTYHR LKNGQFVSFE NRAFEQLQRV
FRQLEAAEQD QLEAVLRAPA LPNLKHLVGA SFLHVHKQLT ERWLELKNGT GVYLNFPEVL
DRHLYPYQRA GIQFMANLAG HDGHGILADE MGLGKTIQAI GYLETLPPGR VLIVAPASLL
HNWQAELTRF APTRTVHLLT GARKHRLDQI ETVPADGIFL ISYPSLRADM EAHQAVEYDV
VIFDEAQHLK NPASQTAVRL RRIRAKRRFA LTGTPLENRT DDLWSIFRVI FPSLLPDLQT
FQTWSHDEIK RFIRPFLMRR TKDEVLQDLP KKQIVHHYTD LGPTQKKLYA SYLAKLQLET
LQHLDETKRE DRIKLLAGLT RLRQICCDPA LFVEDYTGES TKLERLLTLI EEKLAAGHRI
LIFSQYTKML ARIRERLAAQ QRAHFLLTGE TPVEDRVALC ERFNAGEVDL FLISLKAGGT
GLNLATADTV ILYDSWWNPA VEQQAADRAH RLGQQSPVEV IKLLMTGTIE EKMAELQDRK
ATMIDAVLSD QKPDILTIRE LVRLLDSPAF IDSAGE
//
