ID B1YLG3_EXIS2 Unreviewed; 473 AA.
AC B1YLG3;
DT 20-MAY-2008, integrated into UniProtKB/TrEMBL.
DT 20-MAY-2008, sequence version 1.
DT 27-MAR-2024, entry version 104.
DE SubName: Full=Carboxyl-terminal protease {ECO:0000313|EMBL:ACB61868.1};
DE EC=3.4.21.102 {ECO:0000313|EMBL:ACB61868.1};
GN OrderedLocusNames=Exig_2418 {ECO:0000313|EMBL:ACB61868.1};
OS Exiguobacterium sibiricum (strain DSM 17290 / CIP 109462 / JCM 13490 /
OS 255-15).
OC Bacteria; Bacillota; Bacilli; Bacillales;
OC Bacillales Family XII. Incertae Sedis; Exiguobacterium.
OX NCBI_TaxID=262543 {ECO:0000313|EMBL:ACB61868.1, ECO:0000313|Proteomes:UP000001681};
RN [1] {ECO:0000313|EMBL:ACB61868.1, ECO:0000313|Proteomes:UP000001681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17290 / CIP 109462 / JCM 13490 / 255-15
RC {ECO:0000313|Proteomes:UP000001681};
RX PubMed=16489412; DOI=10.1007/s00792-005-0497-5;
RA Rodrigues D.F., Goris J., Vishnivetskaya T., Gilichinsky D.,
RA Thomashow M.F., Tiedje J.M.;
RT "Characterization of Exiguobacterium isolates from the Siberian permafrost.
RT Description of Exiguobacterium sibiricum sp. nov.";
RL Extremophiles 10:285-294(2006).
RN [2] {ECO:0000313|EMBL:ACB61868.1, ECO:0000313|Proteomes:UP000001681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17290 / CIP 109462 / JCM 13490 / 255-15
RC {ECO:0000313|Proteomes:UP000001681};
RX PubMed=19019206; DOI=10.1186/1471-2164-9-547;
RA Rodrigues D.F., Ivanova N., He Z., Huebner M., Zhou J., Tiedje J.M.;
RT "Architecture of thermal adaptation in an Exiguobacterium sibiricum strain
RT isolated from 3 million year old permafrost: a genome and transcriptome
RT approach.";
RL BMC Genomics 9:547-547(2008).
RN [3] {ECO:0000313|Proteomes:UP000001681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17290 / CIP 109462 / JCM 13490 / 255-15
RC {ECO:0000313|Proteomes:UP000001681};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kiss H., Chertkov O., Monk C.,
RA Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F.,
RA Land M., Hauser L., Kyrpides N., Mikhailova N., Vishnivetskaya T.,
RA Rodrigues D.F., Gilichinsky D., Tiedje J., Richardson P.;
RT "Complete sequence of chromosome of Exiguobacterium sibiricum 255-15.";
RL Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S41A family.
CC {ECO:0000256|ARBA:ARBA00009179, ECO:0000256|RuleBase:RU004404}.
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DR EMBL; CP001022; ACB61868.1; -; Genomic_DNA.
DR RefSeq; WP_012371284.1; NC_010556.1.
DR AlphaFoldDB; B1YLG3; -.
DR STRING; 262543.Exig_2418; -.
DR MEROPS; S41.007; -.
DR KEGG; esi:Exig_2418; -.
DR eggNOG; COG0793; Bacteria.
DR eggNOG; COG3409; Bacteria.
DR HOGENOM; CLU_017295_3_0_9; -.
DR OrthoDB; 9812068at2; -.
DR Proteomes; UP000001681; Chromosome.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-EC.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00988; PDZ_CTP_protease; 1.
DR CDD; cd07560; Peptidase_S41_CPP; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 3.30.750.44; -; 1.
DR Gene3D; 1.10.101.10; PGBD-like superfamily/PGBD; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR041489; PDZ_6.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR004447; Peptidase_S41A.
DR InterPro; IPR002477; Peptidoglycan-bd-like.
DR InterPro; IPR036365; PGBD-like_sf.
DR InterPro; IPR036366; PGBDSf.
DR InterPro; IPR005151; Tail-specific_protease.
DR NCBIfam; TIGR00225; prc; 1.
DR PANTHER; PTHR32060:SF29; CARBOXY-TERMINAL PROCESSING PROTEASE CTPB; 1.
DR PANTHER; PTHR32060; TAIL-SPECIFIC PROTEASE; 1.
DR Pfam; PF17820; PDZ_6; 1.
DR Pfam; PF03572; Peptidase_S41; 1.
DR Pfam; PF01471; PG_binding_1; 1.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00245; TSPc; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF47090; PGBD-like; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|RuleBase:RU004404, ECO:0000313|EMBL:ACB61868.1};
KW Protease {ECO:0000256|RuleBase:RU004404, ECO:0000313|EMBL:ACB61868.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001681};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825,
KW ECO:0000256|RuleBase:RU004404}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..473
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002770894"
FT DOMAIN 98..176
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
SQ SEQUENCE 473 AA; 50797 MW; 310DF50B6D271065 CRC64;
MKKSTTAVIA VSTFGLGLGA GAVGMLAAGG TDSVATSSSS NATGDWKKID QVRQMISQNY
LEDVTDQELL EGALTGMTEV LDDPYSVYMD ESETASFNTN LSSSFEGIGA TLEQKGESIV
IVSPIKGSPA EKAGIKPGDI ILEIDGKSTK GQKTDQAVKK IRGEKGTKVV LMIQRGGQDP
MKISIVRDTI PIETVYSKTE KVNGKTIGVL QVTQFSDPTA KEFEKQLAAL EEKNIDGLVI
DVRGNPGGLL TAVSQMIAPF IPKDTPIFQV EDNKGERTQE FGKAEEKKPY KLVVLEDSGS
ASASEILAAG LKEGAGAEVV GTKSFGKGIV QSAYDLKDGS DLKLTTNKWL TPDGNWIHKK
GVKPTVEVKQ PDYFNVTKIL TDNKTLASGD YGKPVENAHL VLEAIGFDPK GQDGYFGDTM
KQAVERLQKD AKLEVTGKIN QVTASEMETR LLKKLEDEKN DVQRIKALEV AAQ
//
