ID B1YLM2_EXIS2 Unreviewed; 493 AA.
AC B1YLM2;
DT 20-MAY-2008, integrated into UniProtKB/TrEMBL.
DT 20-MAY-2008, sequence version 1.
DT 27-MAR-2024, entry version 88.
DE SubName: Full=Cell wall hydrolase/autolysin {ECO:0000313|EMBL:ACB61927.1};
GN OrderedLocusNames=Exig_2477 {ECO:0000313|EMBL:ACB61927.1};
OS Exiguobacterium sibiricum (strain DSM 17290 / CIP 109462 / JCM 13490 /
OS 255-15).
OC Bacteria; Bacillota; Bacilli; Bacillales;
OC Bacillales Family XII. Incertae Sedis; Exiguobacterium.
OX NCBI_TaxID=262543 {ECO:0000313|EMBL:ACB61927.1, ECO:0000313|Proteomes:UP000001681};
RN [1] {ECO:0000313|EMBL:ACB61927.1, ECO:0000313|Proteomes:UP000001681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17290 / CIP 109462 / JCM 13490 / 255-15
RC {ECO:0000313|Proteomes:UP000001681};
RX PubMed=16489412; DOI=10.1007/s00792-005-0497-5;
RA Rodrigues D.F., Goris J., Vishnivetskaya T., Gilichinsky D.,
RA Thomashow M.F., Tiedje J.M.;
RT "Characterization of Exiguobacterium isolates from the Siberian permafrost.
RT Description of Exiguobacterium sibiricum sp. nov.";
RL Extremophiles 10:285-294(2006).
RN [2] {ECO:0000313|EMBL:ACB61927.1, ECO:0000313|Proteomes:UP000001681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17290 / CIP 109462 / JCM 13490 / 255-15
RC {ECO:0000313|Proteomes:UP000001681};
RX PubMed=19019206; DOI=10.1186/1471-2164-9-547;
RA Rodrigues D.F., Ivanova N., He Z., Huebner M., Zhou J., Tiedje J.M.;
RT "Architecture of thermal adaptation in an Exiguobacterium sibiricum strain
RT isolated from 3 million year old permafrost: a genome and transcriptome
RT approach.";
RL BMC Genomics 9:547-547(2008).
RN [3] {ECO:0000313|Proteomes:UP000001681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17290 / CIP 109462 / JCM 13490 / 255-15
RC {ECO:0000313|Proteomes:UP000001681};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kiss H., Chertkov O., Monk C.,
RA Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F.,
RA Land M., Hauser L., Kyrpides N., Mikhailova N., Vishnivetskaya T.,
RA Rodrigues D.F., Gilichinsky D., Tiedje J., Richardson P.;
RT "Complete sequence of chromosome of Exiguobacterium sibiricum 255-15.";
RL Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family.
CC {ECO:0000256|ARBA:ARBA00010860}.
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DR EMBL; CP001022; ACB61927.1; -; Genomic_DNA.
DR AlphaFoldDB; B1YLM2; -.
DR STRING; 262543.Exig_2477; -.
DR KEGG; esi:Exig_2477; -.
DR eggNOG; COG0860; Bacteria.
DR HOGENOM; CLU_014322_1_0_9; -.
DR OrthoDB; 9806267at2; -.
DR Proteomes; UP000001681; Chromosome.
DR GO; GO:0008745; F:N-acetylmuramoyl-L-alanine amidase activity; IEA:InterPro.
DR GO; GO:0009253; P:peptidoglycan catabolic process; IEA:InterPro.
DR CDD; cd02696; MurNAc-LAA; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 4.
DR Gene3D; 3.40.630.40; Zn-dependent exopeptidases; 1.
DR InterPro; IPR002508; MurNAc-LAA_cat.
DR InterPro; IPR003646; SH3-like_bac-type.
DR PANTHER; PTHR30404; N-ACETYLMURAMOYL-L-ALANINE AMIDASE; 1.
DR PANTHER; PTHR30404:SF0; N-ACETYLMURAMOYL-L-ALANINE AMIDASE AMIC; 1.
DR Pfam; PF01520; Amidase_3; 1.
DR Pfam; PF08239; SH3_3; 3.
DR SMART; SM00646; Ami_3; 1.
DR SMART; SM00287; SH3b; 4.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
DR PROSITE; PS51781; SH3B; 3.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:ACB61927.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001681};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..493
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002773794"
FT DOMAIN 36..98
FT /note="SH3b"
FT /evidence="ECO:0000259|PROSITE:PS51781"
FT DOMAIN 104..166
FT /note="SH3b"
FT /evidence="ECO:0000259|PROSITE:PS51781"
FT DOMAIN 168..230
FT /note="SH3b"
FT /evidence="ECO:0000259|PROSITE:PS51781"
SQ SEQUENCE 493 AA; 52677 MW; 127C6A75AC67EC01 CRC64;
MDKLTKILTM TLVLLLLVTI AFPSSLVSAA SGVTFTKTTY QTTDLLNLRS SDSVSSKKLT
TIPKKTSLTS NYRIGDWYLV THNGKTGYVL GQYLTKVVSG TAFAKTAYQT TDALSLRQDA
STSSVRLLTI PVKTTVTSSF RDGNWYKVTY NNKTGFVSGA YLKKVTASST AYTTTERLNF
RTAPTTSGAL LMTIPSNQVV QSLSVSSNWH KISYGGKTGY VMGTYLKKET ASPTVPTAGT
ADYSGSKMYV LIDAGSTVAL RASASVLSGQ ITRLGRGTPV VVTNNLHKTR GFLAVQTADG
RRGYVEATYL TLFQPSPANR PLIVLDPGHG AYDPGAVRAG LAERDIVLSV ARQVAGLLAG
KVDLTLTRYT NDYYPSLGDR SAMANALSTS RFVSIHINAS NGTSASGAES YYYKGTTSVQ
LAQAIQQRLT GYAGMRDRGV HFANYAVIRG TQAPAVLAEL GFLSNASDRA KLADPAYQAR
YAQAIADGIL ATL
//
