ID B1YML3_EXIS2 Unreviewed; 342 AA.
AC B1YML3;
DT 20-MAY-2008, integrated into UniProtKB/TrEMBL.
DT 20-MAY-2008, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE SubName: Full=NAD-dependent epimerase/dehydratase {ECO:0000313|EMBL:ACB62073.1};
GN OrderedLocusNames=Exig_2625 {ECO:0000313|EMBL:ACB62073.1};
OS Exiguobacterium sibiricum (strain DSM 17290 / CIP 109462 / JCM 13490 /
OS 255-15).
OC Bacteria; Bacillota; Bacilli; Bacillales;
OC Bacillales Family XII. Incertae Sedis; Exiguobacterium.
OX NCBI_TaxID=262543 {ECO:0000313|EMBL:ACB62073.1, ECO:0000313|Proteomes:UP000001681};
RN [1] {ECO:0000313|EMBL:ACB62073.1, ECO:0000313|Proteomes:UP000001681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17290 / CIP 109462 / JCM 13490 / 255-15
RC {ECO:0000313|Proteomes:UP000001681};
RX PubMed=16489412; DOI=10.1007/s00792-005-0497-5;
RA Rodrigues D.F., Goris J., Vishnivetskaya T., Gilichinsky D.,
RA Thomashow M.F., Tiedje J.M.;
RT "Characterization of Exiguobacterium isolates from the Siberian permafrost.
RT Description of Exiguobacterium sibiricum sp. nov.";
RL Extremophiles 10:285-294(2006).
RN [2] {ECO:0000313|EMBL:ACB62073.1, ECO:0000313|Proteomes:UP000001681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17290 / CIP 109462 / JCM 13490 / 255-15
RC {ECO:0000313|Proteomes:UP000001681};
RX PubMed=19019206; DOI=10.1186/1471-2164-9-547;
RA Rodrigues D.F., Ivanova N., He Z., Huebner M., Zhou J., Tiedje J.M.;
RT "Architecture of thermal adaptation in an Exiguobacterium sibiricum strain
RT isolated from 3 million year old permafrost: a genome and transcriptome
RT approach.";
RL BMC Genomics 9:547-547(2008).
RN [3] {ECO:0000313|Proteomes:UP000001681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17290 / CIP 109462 / JCM 13490 / 255-15
RC {ECO:0000313|Proteomes:UP000001681};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kiss H., Chertkov O., Monk C.,
RA Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F.,
RA Land M., Hauser L., Kyrpides N., Mikhailova N., Vishnivetskaya T.,
RA Rodrigues D.F., Gilichinsky D., Tiedje J., Richardson P.;
RT "Complete sequence of chromosome of Exiguobacterium sibiricum 255-15.";
RL Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP001022; ACB62073.1; -; Genomic_DNA.
DR RefSeq; WP_012371489.1; NC_010556.1.
DR AlphaFoldDB; B1YML3; -.
DR STRING; 262543.Exig_2625; -.
DR KEGG; esi:Exig_2625; -.
DR eggNOG; COG0451; Bacteria.
DR HOGENOM; CLU_007383_1_7_9; -.
DR Proteomes; UP000001681; Chromosome.
DR CDD; cd05253; UDP_GE_SDE_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR001509; Epimerase_deHydtase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43574; EPIMERASE-RELATED; 1.
DR PANTHER; PTHR43574:SF86; UDP-GLUCOSE 4-EPIMERASE_UDP-SULFOQUINOVOSE SYNTHASE; 1.
DR Pfam; PF01370; Epimerase; 1.
DR PRINTS; PR01713; NUCEPIMERASE.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001681}.
FT DOMAIN 6..239
FT /note="NAD-dependent epimerase/dehydratase"
FT /evidence="ECO:0000259|Pfam:PF01370"
SQ SEQUENCE 342 AA; 39377 MW; ADD541C965D8B693 CRC64;
MINNKILITG ALGFIGFHLS NKLLSMGIEV IGLDNENNYY DVNLKKNRFE KIKSDYKDSF
YFYKIDITDR EKLNTLFEKH NIEIVINLAA QAGVRYSIEN PYAYLDSNLT GFLNILEACR
NYPVKHLLYA SSSSVYGGNK VAPFSTNHNV DHPVSLYAAT KKSNELMAHT YSHLYDIPTT
GLRFFTVYGP WGRPDMAYFS FTKDIVEGNP IKVFNHGKME RDFTYIDDIV EGIVKLIPRA
PQKNPDWDES KDELGASFAP YRVYNIGNNQ PVQLMKFINV LEEKIGKEAN KKYMEMQPGD
VLRTYADVSE LERDIDFKPS TSIEEGLGKF VDWYKEYYNV KL
//
