ID B1ZB58_METPB Unreviewed; 853 AA.
AC B1ZB58;
DT 20-MAY-2008, integrated into UniProtKB/TrEMBL.
DT 20-MAY-2008, sequence version 1.
DT 27-MAR-2024, entry version 112.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN OrderedLocusNames=Mpop_2493 {ECO:0000313|EMBL:ACB80654.1};
OS Methylorubrum populi (strain ATCC BAA-705 / NCIMB 13946 / BJ001)
OS (Methylobacterium populi).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Methylobacteriaceae; Methylorubrum.
OX NCBI_TaxID=441620 {ECO:0000313|EMBL:ACB80654.1, ECO:0000313|Proteomes:UP000007136};
RN [1] {ECO:0000313|EMBL:ACB80654.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BJ001 {ECO:0000313|EMBL:ACB80654.1};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C.,
RA Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L.,
RA Kyrpides N., Mikhailova N., Marx C., Richardson P.;
RT "Complete sequence of chromosome of Methylobacterium populi BJ001.";
RL Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP001029; ACB80654.1; -; Genomic_DNA.
DR RefSeq; WP_012454384.1; NC_010725.1.
DR AlphaFoldDB; B1ZB58; -.
DR STRING; 441620.Mpop_2493; -.
DR KEGG; mpo:Mpop_2493; -.
DR eggNOG; COG2205; Bacteria.
DR HOGENOM; CLU_000445_23_1_5; -.
DR OrthoDB; 9801651at2; -.
DR Proteomes; UP000007136; Chromosome.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43047:SF72; OSMOSENSING HISTIDINE PROTEIN KINASE SLN1; 1.
DR PANTHER; PTHR43047; TWO-COMPONENT HISTIDINE PROTEIN KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF13188; PAS_8; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:ACB80654.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000313|EMBL:ACB80654.1}.
FT DOMAIN 494..564
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 634..853
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT REGION 137..182
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 292..320
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 853 AA; 89605 MW; 3C1680CB2EDA21D5 CRC64;
MSDHAVQDSL PGDDSAVLAA LTRWRGDAST AHLVREGGAL LVLDGGAERI LHAAGAALAL
RAGVAGADGT VLPALRLPEQ IRRAGTLDAR PRMVRLRFDP RGVAPPVVVL AARAEMELGR
SVLLLAPIGA LPSLRPFEAG PAKAEPPSQR ASQPDAQPEA STPAPAPSPA MEMEAGPDQR
ETTADLPARL IWRSDAEGVL TQVSRTHPDL AEALLGQSWA MLAIDGVIEG AALTEALSAR
RTFRSVPLLV RGRAYEHALE ISGAPAGRAT EDFSGFGGFA ILGERSPRAI EEDAAAETES
GGSDAPRDAE PVGGPDVEDG LSVNEHAAFR EVARILGLRF APDLSAEAVE AGSADSATVS
SVTPFPTPPG RIGESEARAR AALTELLESL PLGVLVYRGS EILFASRAFL DLTGYPDLSA
LREAGLAHLF RGLPPGEREI AGPVPFAQSE GGTVALLVDR AGLVWEGAPA ELCLARAAPA
AAALQLPAVP PNAARSRAEK VLESLEEGVV TLDAEGRVVG LNPSAAELVH AHPKEVVGGR
FADLFAPESL PALETAVTDS RRSGASEIHG VTPRTGAAAL RLRIARLLGE DAPGYCASLR
EIRDDEPALP AAGEPARREA SEAEAEWKAN ALARVSREIR PSLNAILSLT EMMLSDRFDR
ADAERLEAYL REVRLSGGRI AGLIDDLRDL AEIQAGRGKL TFAELALNEL VSSCIAAQQA
QAARDRIVLR TSLAPDLPAM RADMRSIRQA TLTVLGNAIR VTEAGGQVIV STTRAERGGI
ALRVRDTGTG MTEDELMGAL EPFRADIAPA AEGEERGFGL TLTKALVEAN RGRFRITSRK
DEGTLVEMLF PAA
//
