ID   B1ZXS1_OPITP            Unreviewed;       688 AA.
AC   B1ZXS1;
DT   20-MAY-2008, integrated into UniProtKB/TrEMBL.
DT   20-MAY-2008, sequence version 1.
DT   27-MAR-2024, entry version 77.
DE   RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE            EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN   OrderedLocusNames=Oter_1005 {ECO:0000313|EMBL:ACB74293.1};
OS   Opitutus terrae (strain DSM 11246 / JCM 15787 / PB90-1).
OC   Bacteria; Verrucomicrobiota; Opitutae; Opitutales; Opitutaceae; Opitutus.
OX   NCBI_TaxID=452637 {ECO:0000313|EMBL:ACB74293.1, ECO:0000313|Proteomes:UP000007013};
RN   [1] {ECO:0000313|EMBL:ACB74293.1, ECO:0000313|Proteomes:UP000007013}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 11246 / JCM 15787 / PB90-1
RC   {ECO:0000313|Proteomes:UP000007013};
RX   PubMed=21398538; DOI=10.1128/JB.00228-11;
RA   van Passel M.W., Kant R., Palva A., Copeland A., Lucas S., Lapidus A.,
RA   Glavina del Rio T., Pitluck S., Goltsman E., Clum A., Sun H., Schmutz J.,
RA   Larimer F.W., Land M.L., Hauser L., Kyrpides N., Mikhailova N.,
RA   Richardson P.P., Janssen P.H., de Vos W.M., Smidt H.;
RT   "Genome sequence of the verrucomicrobium Opitutus terrae PB90-1, an
RT   abundant inhabitant of rice paddy soil ecosystems.";
RL   J. Bacteriol. 193:2367-2368(2011).
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC       {ECO:0000256|ARBA:ARBA00006285}.
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DR   EMBL; CP001032; ACB74293.1; -; Genomic_DNA.
DR   AlphaFoldDB; B1ZXS1; -.
DR   STRING; 452637.Oter_1005; -.
DR   CAZy; GH20; Glycoside Hydrolase Family 20.
DR   KEGG; ote:Oter_1005; -.
DR   eggNOG; COG3525; Bacteria.
DR   HOGENOM; CLU_007082_5_1_0; -.
DR   Proteomes; UP000007013; Chromosome.
DR   GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   CDD; cd06570; GH20_chitobiase-like_1; 1.
DR   Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR   InterPro; IPR015883; Glyco_hydro_20_cat.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR029018; Hex-like_dom2.
DR   InterPro; IPR029019; HEX_eukaryotic_N.
DR   PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR   PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR   Pfam; PF00728; Glyco_hydro_20; 1.
DR   Pfam; PF14845; Glycohydro_20b2; 1.
DR   PRINTS; PR00738; GLHYDRLASE20.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000313|EMBL:ACB74293.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:ACB74293.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007013};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           17..688
FT                   /note="beta-N-acetylhexosaminidase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5002772215"
FT   DOMAIN          23..142
FT                   /note="Beta-hexosaminidase eukaryotic type N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14845"
FT   DOMAIN          163..473
FT                   /note="Glycoside hydrolase family 20 catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF00728"
FT   ACT_SITE        319
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ   SEQUENCE   688 AA;  75742 MW;  A1BD8D7F8DB9F34F CRC64;
     MLLAMLAVAL PVSISAAPAP HDLLPAPAQL AFAEGRLPVT AEFSVSLRGH DDARLRAGLS
     RALRRWEERT GFTFARTPQA EFVLASDTSR AALVVECSAA GSALPTLGED ESYSLEVSPA
     QAVLRAPNVV GALRGFETLL QLLQRDARGW FVPVVKIQDA PRFPWRGLMI DVCRHWQPME
     VLKRNLDGMA LVKLNVLHLH LTEDQGFRIE SKTHPRLHEL GSDGLYFTQD QIREIIAYAA
     ARGIRVVPEF DMPGHATSWA VAYPELASAP GPYVIERGWG IFDPVLDPTN EKVYALLEDF
     LGEMAALFPD PYLHIGGDEN NGKHWNANAR IQAFIREHDL KDNEGLHATF NRRVRDILTK
     HGKKMVGWDE ILHPDLPQDA IVHSWRGPTG LAAAAKAGHA AILSNGYYID LCYSAADHYR
     NDPLPADTAI PLAEQSRILG GEATMWAEWV SPETIDSRIW PRTAAIAERL WSPRDVNDVA
     DMYRRLAIVS QRLEETGLNH ERNRPAMLRR LAGDGASAED LENLRIFVEA VEPVKGYERG
     RYHAEHRQAT PLTRVADCAR PESNTAREFT VAVDRLLGGA RRPDGHSAAA LQELREQLLA
     WQAAGLEVAD LLTQRALLGR DSAPVAKSLA EASAVGLAAL EAIARGDARD PAWRTEQFTV
     LERAAEPHDA VQLPALGAIR RLVTAAAP
//