ID B2A1E9_NATTJ Unreviewed; 636 AA.
AC B2A1E9;
DT 20-MAY-2008, integrated into UniProtKB/TrEMBL.
DT 20-MAY-2008, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE SubName: Full=Helicase c2 {ECO:0000313|EMBL:ACB84689.1};
GN OrderedLocusNames=Nther_1106 {ECO:0000313|EMBL:ACB84689.1};
OS Natranaerobius thermophilus (strain ATCC BAA-1301 / DSM 18059 /
OS JW/NM-WN-LF).
OC Bacteria; Bacillota; Clostridia; Natranaerobiales; Natranaerobiaceae;
OC Natranaerobius.
OX NCBI_TaxID=457570 {ECO:0000313|EMBL:ACB84689.1, ECO:0000313|Proteomes:UP000001683};
RN [1] {ECO:0000313|EMBL:ACB84689.1, ECO:0000313|Proteomes:UP000001683}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1301 / DSM 18059 / JW/NM-WN-LF
RC {ECO:0000313|Proteomes:UP000001683};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C.,
RA Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L.,
RA Kyrpides N., Lykidis A., Mesbah N.M., Wiegel J.;
RT "Complete sequence of chromosome of Natranaerobius thermophilus JW/NM-WN-
RT LF.";
RL Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACB84689.1, ECO:0000313|Proteomes:UP000001683}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1301 / DSM 18059 / JW/NM-WN-LF
RC {ECO:0000313|Proteomes:UP000001683};
RX PubMed=21642468; DOI=10.1128/JB.05157-11;
RA Zhao B., Mesbah N.M., Dalin E., Goodwin L., Nolan M., Pitluck S.,
RA Chertkov O., Brettin T.S., Han J., Larimer F.W., Land M.L., Hauser L.,
RA Kyrpides N., Wiegel J.;
RT "Complete genome sequence of the anaerobic, halophilic alkalithermophile
RT Natranaerobius thermophilus JW/NM-WN-LF.";
RL J. Bacteriol. 193:4023-4024(2011).
CC -!- SIMILARITY: Belongs to the helicase family. DinG subfamily.
CC {ECO:0000256|ARBA:ARBA00038058}.
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DR EMBL; CP001034; ACB84689.1; -; Genomic_DNA.
DR RefSeq; WP_012447564.1; NC_010718.1.
DR AlphaFoldDB; B2A1E9; -.
DR STRING; 457570.Nther_1106; -.
DR KEGG; nth:Nther_1106; -.
DR eggNOG; COG1199; Bacteria.
DR HOGENOM; CLU_012117_2_0_9; -.
DR InParanoid; B2A1E9; -.
DR OrthoDB; 9803913at2; -.
DR Proteomes; UP000001683; Chromosome.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR006555; ATP-dep_Helicase_C.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR045028; DinG/Rad3-like.
DR InterPro; IPR014013; Helic_SF1/SF2_ATP-bd_DinG/Rad3.
DR InterPro; IPR006554; Helicase-like_DEXD_c2.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11472; DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER; 1.
DR PANTHER; PTHR11472:SF47; FANCONI ANEMIA GROUP J PROTEIN; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF13307; Helicase_C_2; 1.
DR SMART; SM00488; DEXDc2; 1.
DR SMART; SM00491; HELICc2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51193; HELICASE_ATP_BIND_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:ACB84689.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000001683}.
FT DOMAIN 14..319
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51193"
SQ SEQUENCE 636 AA; 72987 MW; 021F9F8BB7AAC640 CRC64;
MSSQWEELDQ IWEDLQHHID KFETREGQID MSLGVLKALQ DGGHFVVEAG TGTGKSLAYL
LPAVQLAQDE FRMVISTATI ALQEQLLQKD IPLVEKIIGR TLRVEVIKGR SNYLCKQKFN
QHFGQTSFVN SIQERELIEW VNETETGDRN ELQTMPEIWE KVCSQSESCL AMRCQFYSEC
FVVKLRKRAE TAELLVTNHH LYFSDLNLRI DSDGSMSIFP DYEGVIFDEA HHIPDTATKS
LGREVKYSRV IKLFKEVTSY LKQKFQAQVN LVQEAEASAV KAFNKLSDFR ESDYLLRELD
SFISLKEFRK KLSKLAQHVE ECALEEMDRP EQPRMLASRL NKTKLDLDLI LDLEEEDYIS
WVNQQSSDIS LSTNPVFVHK QLREFLFDNV DRIIMTSATL SINGKFAYFK NRVGLSQDAQ
TYQIESPFNY QEQSNIYIPK NFPEPRSGEY NRQLADTIEQ IIDAAGGRTL VLFTSYSTLN
SIYNQLKDKV PYEIYCQGIH PKNKILSWFQ NDASSVLMAT NSFREGVDVP GSSLQVVIMD
KLPFAVPDNP LIKAKIEKLQ QEGQNSFMNY QLPEAVLAVK QGFGRLIRHN NDCGIFALLD
PRVFTKSYGR HFINSLPNAP LISNWSELEA KIKTLP
//
