ID B2A1Z1_NATTJ Unreviewed; 338 AA.
AC B2A1Z1;
DT 20-MAY-2008, integrated into UniProtKB/TrEMBL.
DT 20-MAY-2008, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE RecName: Full=Deoxyguanosinetriphosphate triphosphohydrolase-like protein {ECO:0000256|HAMAP-Rule:MF_01212};
GN OrderedLocusNames=Nther_1213 {ECO:0000313|EMBL:ACB84796.1};
OS Natranaerobius thermophilus (strain ATCC BAA-1301 / DSM 18059 /
OS JW/NM-WN-LF).
OC Bacteria; Bacillota; Clostridia; Natranaerobiales; Natranaerobiaceae;
OC Natranaerobius.
OX NCBI_TaxID=457570 {ECO:0000313|EMBL:ACB84796.1, ECO:0000313|Proteomes:UP000001683};
RN [1] {ECO:0000313|EMBL:ACB84796.1, ECO:0000313|Proteomes:UP000001683}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1301 / DSM 18059 / JW/NM-WN-LF
RC {ECO:0000313|Proteomes:UP000001683};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C.,
RA Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L.,
RA Kyrpides N., Lykidis A., Mesbah N.M., Wiegel J.;
RT "Complete sequence of chromosome of Natranaerobius thermophilus JW/NM-WN-
RT LF.";
RL Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACB84796.1, ECO:0000313|Proteomes:UP000001683}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1301 / DSM 18059 / JW/NM-WN-LF
RC {ECO:0000313|Proteomes:UP000001683};
RX PubMed=21642468; DOI=10.1128/JB.05157-11;
RA Zhao B., Mesbah N.M., Dalin E., Goodwin L., Nolan M., Pitluck S.,
RA Chertkov O., Brettin T.S., Han J., Larimer F.W., Land M.L., Hauser L.,
RA Kyrpides N., Wiegel J.;
RT "Complete genome sequence of the anaerobic, halophilic alkalithermophile
RT Natranaerobius thermophilus JW/NM-WN-LF.";
RL J. Bacteriol. 193:4023-4024(2011).
CC -!- SIMILARITY: Belongs to the dGTPase family. Type 2 subfamily.
CC {ECO:0000256|HAMAP-Rule:MF_01212}.
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DR EMBL; CP001034; ACB84796.1; -; Genomic_DNA.
DR RefSeq; WP_012447671.1; NC_010718.1.
DR AlphaFoldDB; B2A1Z1; -.
DR STRING; 457570.Nther_1213; -.
DR KEGG; nth:Nther_1213; -.
DR eggNOG; COG0232; Bacteria.
DR HOGENOM; CLU_028163_1_1_9; -.
DR InParanoid; B2A1Z1; -.
DR OrthoDB; 9803619at2; -.
DR Proteomes; UP000001683; Chromosome.
DR GO; GO:0016793; F:triphosphoric monoester hydrolase activity; IEA:InterPro.
DR CDD; cd00077; HDc; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR HAMAP; MF_01212; dGTPase_type2; 1.
DR InterPro; IPR006261; dNTPase.
DR InterPro; IPR023023; dNTPase_2.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR026875; PHydrolase_assoc_dom.
DR NCBIfam; TIGR01353; dGTP_triPase; 1.
DR PANTHER; PTHR35795:SF1; BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE, SYMMETRICAL; 1.
DR PANTHER; PTHR35795; SLR1885 PROTEIN; 1.
DR Pfam; PF01966; HD; 1.
DR Pfam; PF13286; HD_assoc; 1.
DR SMART; SM00471; HDc; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR PROSITE; PS51831; HD; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|HAMAP-Rule:MF_01212, ECO:0000313|EMBL:ACB84796.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001683}.
FT DOMAIN 76..187
FT /note="HD"
FT /evidence="ECO:0000259|PROSITE:PS51831"
SQ SEQUENCE 338 AA; 38770 MW; 1668A2BAE3F36D77 CRC64;
MVSFREKLEK LETETLSQKA TFSQNTRGRL SPETECKVRT AFQKDRDRIL HSKAFRRLKH
KTQVFISPEG DHYRTRLTHT LEVAQIARTV AKALFLNEDL TEAIALGHDL GHTPFGHAGE
MVLNELVNDG GFQHNNQSLR VVDFLERPGG LNLTQEVRDG IKNHTGDITP VSLEGQIVKI
CDRIAYINHD IDDALRGEII SQKQLPESSG NVLGNTSNSR IDTMVCDLIE TSYKNGEVSM
STRVKTAMEE LREFLFQNVY VGSKAKEEES KAEYVIKAVY DYFYNEPEKL PNDVYSMIDQ
VGRERLVCDY VAGMTDRYIL DLYRDIFLPK PWRFNREE
//
