ID B2A492_NATTJ Unreviewed; 344 AA.
AC B2A492;
DT 20-MAY-2008, integrated into UniProtKB/TrEMBL.
DT 20-MAY-2008, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE SubName: Full=Metal dependent phosphohydrolase {ECO:0000313|EMBL:ACB83746.1};
GN OrderedLocusNames=Nther_0147 {ECO:0000313|EMBL:ACB83746.1};
OS Natranaerobius thermophilus (strain ATCC BAA-1301 / DSM 18059 /
OS JW/NM-WN-LF).
OC Bacteria; Bacillota; Clostridia; Natranaerobiales; Natranaerobiaceae;
OC Natranaerobius.
OX NCBI_TaxID=457570 {ECO:0000313|EMBL:ACB83746.1, ECO:0000313|Proteomes:UP000001683};
RN [1] {ECO:0000313|EMBL:ACB83746.1, ECO:0000313|Proteomes:UP000001683}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1301 / DSM 18059 / JW/NM-WN-LF
RC {ECO:0000313|Proteomes:UP000001683};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C.,
RA Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L.,
RA Kyrpides N., Lykidis A., Mesbah N.M., Wiegel J.;
RT "Complete sequence of chromosome of Natranaerobius thermophilus JW/NM-WN-
RT LF.";
RL Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACB83746.1, ECO:0000313|Proteomes:UP000001683}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1301 / DSM 18059 / JW/NM-WN-LF
RC {ECO:0000313|Proteomes:UP000001683};
RX PubMed=21642468; DOI=10.1128/JB.05157-11;
RA Zhao B., Mesbah N.M., Dalin E., Goodwin L., Nolan M., Pitluck S.,
RA Chertkov O., Brettin T.S., Han J., Larimer F.W., Land M.L., Hauser L.,
RA Kyrpides N., Wiegel J.;
RT "Complete genome sequence of the anaerobic, halophilic alkalithermophile
RT Natranaerobius thermophilus JW/NM-WN-LF.";
RL J. Bacteriol. 193:4023-4024(2011).
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DR EMBL; CP001034; ACB83746.1; -; Genomic_DNA.
DR RefSeq; WP_012446637.1; NC_010718.1.
DR AlphaFoldDB; B2A492; -.
DR STRING; 457570.Nther_0147; -.
DR KEGG; nth:Nther_0147; -.
DR eggNOG; COG3481; Bacteria.
DR HOGENOM; CLU_056349_2_0_9; -.
DR InParanoid; B2A492; -.
DR OrthoDB; 9778453at2; -.
DR Proteomes; UP000001683; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd00077; HDc; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR006675; HDIG_dom.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR004365; NA-bd_OB_tRNA.
DR NCBIfam; TIGR00277; HDIG; 1.
DR PANTHER; PTHR37294; 3'-5' EXORIBONUCLEASE YHAM; 1.
DR PANTHER; PTHR37294:SF1; 3'-5' EXORIBONUCLEASE YHAM; 1.
DR Pfam; PF01966; HD; 1.
DR Pfam; PF01336; tRNA_anti-codon; 1.
DR SMART; SM00471; HDc; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:ACB83746.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001683}.
FT DOMAIN 161..296
FT /note="HD/PDEase"
FT /evidence="ECO:0000259|SMART:SM00471"
SQ SEQUENCE 344 AA; 39587 MW; 0ED94F07CCD4F00E CRC64;
MKKEQFVKDI NVGDKIDAPF VVVEKKMMDF NTQKKTGEKF MLLRLRDNTG TIKAVLWERA
EQTANYVHED TIVWVKGKTQ EYKGVQIIID EIEAIAEDID LTPFVPSSSI GSEELKKELR
KTIKNINNKY LTELLNTIFE DQKLLSLYLK APAGKKVHHN YLGGLAEHSL EVIKIVSSMY
QLYQDRINWD LLVTGSLLHD IGKIYEYDLN SPSFQMTDRG KLLGHIALGE ELIRSKIDRL
SYFPESLAVE IRHMILSHHG EKEWGSPEVP KTFNALCLFY GDLISSRLNQ VDKLFFEAET
GEQEENFNWT NFDPLMGRAF YLPQEETSEQ IEGSQLSLDN LTES
//
