ID B2A891_NATTJ Unreviewed; 215 AA.
AC B2A891;
DT 20-MAY-2008, integrated into UniProtKB/TrEMBL.
DT 20-MAY-2008, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE RecName: Full=TVP38/TMEM64 family membrane protein {ECO:0000256|RuleBase:RU366058};
GN OrderedLocusNames=Nther_0872 {ECO:0000313|EMBL:ACB84457.1};
OS Natranaerobius thermophilus (strain ATCC BAA-1301 / DSM 18059 /
OS JW/NM-WN-LF).
OC Bacteria; Bacillota; Clostridia; Natranaerobiales; Natranaerobiaceae;
OC Natranaerobius.
OX NCBI_TaxID=457570 {ECO:0000313|EMBL:ACB84457.1, ECO:0000313|Proteomes:UP000001683};
RN [1] {ECO:0000313|EMBL:ACB84457.1, ECO:0000313|Proteomes:UP000001683}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1301 / DSM 18059 / JW/NM-WN-LF
RC {ECO:0000313|Proteomes:UP000001683};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C.,
RA Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L.,
RA Kyrpides N., Lykidis A., Mesbah N.M., Wiegel J.;
RT "Complete sequence of chromosome of Natranaerobius thermophilus JW/NM-WN-
RT LF.";
RL Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACB84457.1, ECO:0000313|Proteomes:UP000001683}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1301 / DSM 18059 / JW/NM-WN-LF
RC {ECO:0000313|Proteomes:UP000001683};
RX PubMed=21642468; DOI=10.1128/JB.05157-11;
RA Zhao B., Mesbah N.M., Dalin E., Goodwin L., Nolan M., Pitluck S.,
RA Chertkov O., Brettin T.S., Han J., Larimer F.W., Land M.L., Hauser L.,
RA Kyrpides N., Wiegel J.;
RT "Complete genome sequence of the anaerobic, halophilic alkalithermophile
RT Natranaerobius thermophilus JW/NM-WN-LF.";
RL J. Bacteriol. 193:4023-4024(2011).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU366058};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU366058}.
CC -!- SIMILARITY: Belongs to the TVP38/TMEM64 family.
CC {ECO:0000256|RuleBase:RU366058}.
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DR EMBL; CP001034; ACB84457.1; -; Genomic_DNA.
DR RefSeq; WP_012447335.1; NC_010718.1.
DR AlphaFoldDB; B2A891; -.
DR STRING; 457570.Nther_0872; -.
DR KEGG; nth:Nther_0872; -.
DR eggNOG; COG0398; Bacteria.
DR HOGENOM; CLU_038944_8_2_9; -.
DR InParanoid; B2A891; -.
DR OrthoDB; 9812980at2; -.
DR Proteomes; UP000001683; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR015414; TMEM64.
DR InterPro; IPR032816; VTT_dom.
DR PANTHER; PTHR12677:SF49; TVP38_TMEM64 FAMILY MEMBRANE PROTEIN; 1.
DR PANTHER; PTHR12677; UNCHARACTERIZED; 1.
DR Pfam; PF09335; SNARE_assoc; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|RuleBase:RU366058};
KW Membrane {ECO:0000256|RuleBase:RU366058};
KW Reference proteome {ECO:0000313|Proteomes:UP000001683};
KW Transmembrane {ECO:0000256|RuleBase:RU366058};
KW Transmembrane helix {ECO:0000256|RuleBase:RU366058}.
FT TRANSMEM 6..23
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366058"
FT TRANSMEM 32..50
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366058"
FT TRANSMEM 62..87
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366058"
FT TRANSMEM 157..177
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366058"
FT TRANSMEM 183..202
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366058"
FT DOMAIN 59..177
FT /note="VTT"
FT /evidence="ECO:0000259|Pfam:PF09335"
SQ SEQUENCE 215 AA; 24682 MW; F5368AC1998013F2 CRC64;
MTILRIIIVL LIGVGTGSYY LYLNDIITAE NIYLFLENYA YLAPLLYFLI HVIRPFTMLP
SSILSVVAGL TFGSWIGFLI CITGFLLGTS TAYIMGKVFQ LKWLISRYPQ SQQLIQVLKE
NSTDNILLGI SLRFVPIFPS DLVSFAFGVC KIRYREFALG TLIGSFPGLF MFYYAGIQFQ
QQSYFNLILI LIAFVILTLI FWKKKQYYKE KFGIK
//
