ID B2A8A4_NATTJ Unreviewed; 300 AA.
AC B2A8A4;
DT 20-MAY-2008, integrated into UniProtKB/TrEMBL.
DT 20-MAY-2008, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=N-acetylmuramoyl-L-alanine amidase {ECO:0000313|EMBL:ACB84470.1};
DE EC=3.5.1.28 {ECO:0000313|EMBL:ACB84470.1};
GN OrderedLocusNames=Nther_0885 {ECO:0000313|EMBL:ACB84470.1};
OS Natranaerobius thermophilus (strain ATCC BAA-1301 / DSM 18059 /
OS JW/NM-WN-LF).
OC Bacteria; Bacillota; Clostridia; Natranaerobiales; Natranaerobiaceae;
OC Natranaerobius.
OX NCBI_TaxID=457570 {ECO:0000313|EMBL:ACB84470.1, ECO:0000313|Proteomes:UP000001683};
RN [1] {ECO:0000313|EMBL:ACB84470.1, ECO:0000313|Proteomes:UP000001683}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1301 / DSM 18059 / JW/NM-WN-LF
RC {ECO:0000313|Proteomes:UP000001683};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C.,
RA Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L.,
RA Kyrpides N., Lykidis A., Mesbah N.M., Wiegel J.;
RT "Complete sequence of chromosome of Natranaerobius thermophilus JW/NM-WN-
RT LF.";
RL Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACB84470.1, ECO:0000313|Proteomes:UP000001683}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1301 / DSM 18059 / JW/NM-WN-LF
RC {ECO:0000313|Proteomes:UP000001683};
RX PubMed=21642468; DOI=10.1128/JB.05157-11;
RA Zhao B., Mesbah N.M., Dalin E., Goodwin L., Nolan M., Pitluck S.,
RA Chertkov O., Brettin T.S., Han J., Larimer F.W., Land M.L., Hauser L.,
RA Kyrpides N., Wiegel J.;
RT "Complete genome sequence of the anaerobic, halophilic alkalithermophile
RT Natranaerobius thermophilus JW/NM-WN-LF.";
RL J. Bacteriol. 193:4023-4024(2011).
CC -!- SIMILARITY: Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family.
CC {ECO:0000256|ARBA:ARBA00010860}.
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DR EMBL; CP001034; ACB84470.1; -; Genomic_DNA.
DR RefSeq; WP_012447348.1; NC_010718.1.
DR AlphaFoldDB; B2A8A4; -.
DR STRING; 457570.Nther_0885; -.
DR KEGG; nth:Nther_0885; -.
DR eggNOG; COG0860; Bacteria.
DR eggNOG; COG3103; Bacteria.
DR HOGENOM; CLU_014322_1_1_9; -.
DR InParanoid; B2A8A4; -.
DR Proteomes; UP000001683; Chromosome.
DR GO; GO:0008745; F:N-acetylmuramoyl-L-alanine amidase activity; IEA:UniProtKB-EC.
DR GO; GO:0009253; P:peptidoglycan catabolic process; IEA:InterPro.
DR CDD; cd02696; MurNAc-LAA; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR Gene3D; 3.40.630.40; Zn-dependent exopeptidases; 1.
DR InterPro; IPR002508; MurNAc-LAA_cat.
DR InterPro; IPR003646; SH3-like_bac-type.
DR PANTHER; PTHR30404; N-ACETYLMURAMOYL-L-ALANINE AMIDASE; 1.
DR PANTHER; PTHR30404:SF0; N-ACETYLMURAMOYL-L-ALANINE AMIDASE AMIC; 1.
DR Pfam; PF01520; Amidase_3; 1.
DR Pfam; PF08239; SH3_3; 1.
DR SMART; SM00646; Ami_3; 1.
DR SMART; SM00287; SH3b; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
DR PROSITE; PS51781; SH3B; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:ACB84470.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001683};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..300
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5039447974"
FT DOMAIN 33..104
FT /note="SH3b"
FT /evidence="ECO:0000259|PROSITE:PS51781"
SQ SEQUENCE 300 AA; 33329 MW; 8DAF5726C19E558E CRC64;
MKGLKLTISL LVFVLLLAAS GPIMGNEVSA EELEEAEVVV ETLNVRSGPG LSNSLIDQVH
QGETYDVLDK QTNESESYYQ DWVKIDFSGY EEAWVSQDYV NITTPEAIDP EPENNSYRPL
EGTRIVLDPG HGGWDPGAVG PTGLTEKEVA LDVSFKTQDK LESLGAEVYL TRESDIDIPL
ANRAYFANDL WADLFISIHA NGAINRGAQG TETHYSSWRN PNDYFLAESL QDSMIDNINR
VDRGIIDSNF AVLTHARMPA ALVELAFISN YEEERLLGSD YFQENAAQGI TEGIVDYFNY
//
