ID B2AW42_PODAN Unreviewed; 361 AA.
AC B2AW42;
DT 20-MAY-2008, integrated into UniProtKB/TrEMBL.
DT 20-MAY-2008, sequence version 1.
DT 24-JAN-2024, entry version 76.
DE RecName: Full=Pre-mRNA-splicing factor 18 {ECO:0000256|ARBA:ARBA00018242};
GN ORFNames=PODANS_7_5880 {ECO:0000313|EMBL:CAP68616.1};
OS Podospora anserina (strain S / ATCC MYA-4624 / DSM 980 / FGSC 10383)
OS (Pleurage anserina).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Podosporaceae; Podospora;
OC Podospora anserina.
OX NCBI_TaxID=515849 {ECO:0000313|EMBL:CAP68616.1};
RN [1] {ECO:0000313|EMBL:CAP68616.1, ECO:0000313|Proteomes:UP000001197}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S / ATCC MYA-4624 / DSM 980 / FGSC 10383
RC {ECO:0000313|Proteomes:UP000001197}, and S mat+
RC {ECO:0000313|EMBL:CAP68616.1};
RX PubMed=18460219; DOI=10.1186/gb-2008-9-5-r77;
RA Espagne E., Lespinet O., Malagnac F., Da Silva C., Jaillon O., Porcel B.M.,
RA Couloux A., Aury J.-M., Segurens B., Poulain J., Anthouard V.,
RA Grossetete S., Khalili H., Coppin E., Dequard-Chablat M., Picard M.,
RA Contamine V., Arnaise S., Bourdais A., Berteaux-Lecellier V., Gautheret D.,
RA de Vries R.P., Battaglia E., Coutinho P.M., Danchin E.G.J., Henrissat B.,
RA El Khoury R., Sainsard-Chanet A., Boivin A., Pinan-Lucarre B., Sellem C.H.,
RA Debuchy R., Wincker P., Weissenbach J., Silar P.;
RT "The genome sequence of the model ascomycete fungus Podospora anserina.";
RL Genome Biol. 9:R77.1-R77.22(2008).
RN [2] {ECO:0000313|EMBL:CAP68616.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=S mat+ {ECO:0000313|EMBL:CAP68616.1};
RA Genoscope - CEA;
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000001197}
RP GENOME REANNOTATION.
RC STRAIN=S / ATCC MYA-4624 / DSM 980 / FGSC 10383
RC {ECO:0000313|Proteomes:UP000001197};
RX PubMed=24558260; DOI=10.1534/genetics.113.159988;
RA Grognet P., Bidard F., Kuchly C., Tong L.C.H., Coppin E., Benkhali J.A.,
RA Couloux A., Wincker P., Debuchy R., Silar P.;
RT "Maintaining two mating types: Structure of the mating type locus and its
RT role in heterokaryosis in Podospora anserina.";
RL Genetics 197:421-432(2014).
RN [4] {ECO:0000313|EMBL:CDP32089.1}
RP NUCLEOTIDE SEQUENCE.
RA Grognet P., Bidard F., Kuchly C., Chan Ho Tong L., Coppin E.,
RA Ait Benkhali J., Couloux A., Wincker P., Debuchy R., Silar P.;
RT "Maintaining two mating types: Structure of the mating type locus and its
RT role in heterokaryosis in Podospora anserina.";
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the PRP18 family.
CC {ECO:0000256|ARBA:ARBA00008137}.
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DR EMBL; CU633900; CAP68616.1; -; Genomic_DNA.
DR EMBL; FO904942; CDP32089.1; -; Genomic_DNA.
DR RefSeq; XP_001907943.1; XM_001907908.1.
DR AlphaFoldDB; B2AW42; -.
DR STRING; 515849.B2AW42; -.
DR GeneID; 6191884; -.
DR KEGG; pan:PODANSg4978; -.
DR VEuPathDB; FungiDB:PODANS_7_5880; -.
DR eggNOG; KOG2808; Eukaryota.
DR HOGENOM; CLU_039675_1_0_1; -.
DR OrthoDB; 199348at2759; -.
DR Proteomes; UP000001197; Chromosome 7.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR Gene3D; 1.20.940.10; Functional domain of the splicing factor Prp18; 1.
DR Gene3D; 4.10.280.110; Pre-mRNA processing factor 4 domain; 1.
DR InterPro; IPR004098; Prp18.
DR InterPro; IPR014906; PRP4-like.
DR InterPro; IPR036285; PRP4-like_sf.
DR InterPro; IPR039979; PRPF18.
DR PANTHER; PTHR13007; PRE-MRNA SPLICING FACTOR-RELATED; 1.
DR PANTHER; PTHR13007:SF19; PRE-MRNA-SPLICING FACTOR 18; 1.
DR Pfam; PF02840; Prp18; 1.
DR Pfam; PF08799; PRP4; 1.
DR SMART; SM00500; SFM; 1.
DR SUPFAM; SSF47938; Functional domain of the splicing factor Prp18; 1.
DR SUPFAM; SSF158230; PRP4-like; 1.
PE 3: Inferred from homology;
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000001197};
KW Spliceosome {ECO:0000256|ARBA:ARBA00022728}.
FT DOMAIN 134..189
FT /note="Pre-mRNA processing factor 4 (PRP4)-like"
FT /evidence="ECO:0000259|SMART:SM00500"
FT REGION 1..135
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7..30
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..125
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 361 AA; 41145 MW; 5046D43FEC1B8DF3 CRC64;
MDFASLMAKE IAKKEPEKEK PQKYISRREA EAQRQAAYLA EQKALEEQRA ARAAAKRKRE
EEAAEEAKAR EEKRQKLAEE SRLRREAKEA EEERARRKRL GLPELPPKTD DDSSATPKPD
SDASSDDDQD HTDIPDDELK SKLRELGQPA ILFGESHVSR LRRYRKVTRP KSLSAGPIAT
KLLPVEEKDM KVPDKIPPAT DRKARKYLYR QLASYFNMIL REWEAALARE DNADTTAGQQ
AINAMVSSKE NMAPLFRLFE KGGLDESILE AIVEIVKAAQ EKRYVDANDG YLRLSIGKAA
WPIGVTMVGI HERSAREKLH NGERGHIMGS EVTRKYLQSI KRCLTFAQVR WPPEDIRQLM
G
//
