ID B2B4B3_PODAN Unreviewed; 991 AA.
AC B2B4B3;
DT 20-MAY-2008, integrated into UniProtKB/TrEMBL.
DT 20-MAY-2008, sequence version 1.
DT 27-MAR-2024, entry version 88.
DE SubName: Full=Oxysterol-binding protein {ECO:0000313|EMBL:CDP25033.1};
DE SubName: Full=Podospora anserina S mat+ genomic DNA chromosome 2, supercontig 2 {ECO:0000313|EMBL:CAP72638.1};
GN ORFNames=PODANS_2_690 {ECO:0000313|EMBL:CAP72638.1};
OS Podospora anserina (strain S / ATCC MYA-4624 / DSM 980 / FGSC 10383)
OS (Pleurage anserina).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Podosporaceae; Podospora;
OC Podospora anserina.
OX NCBI_TaxID=515849 {ECO:0000313|EMBL:CAP72638.1};
RN [1] {ECO:0000313|EMBL:CAP72638.1, ECO:0000313|Proteomes:UP000001197}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S / ATCC MYA-4624 / DSM 980 / FGSC 10383
RC {ECO:0000313|Proteomes:UP000001197}, and S mat+
RC {ECO:0000313|EMBL:CAP72638.1};
RX PubMed=18460219; DOI=10.1186/gb-2008-9-5-r77;
RA Espagne E., Lespinet O., Malagnac F., Da Silva C., Jaillon O., Porcel B.M.,
RA Couloux A., Aury J.-M., Segurens B., Poulain J., Anthouard V.,
RA Grossetete S., Khalili H., Coppin E., Dequard-Chablat M., Picard M.,
RA Contamine V., Arnaise S., Bourdais A., Berteaux-Lecellier V., Gautheret D.,
RA de Vries R.P., Battaglia E., Coutinho P.M., Danchin E.G.J., Henrissat B.,
RA El Khoury R., Sainsard-Chanet A., Boivin A., Pinan-Lucarre B., Sellem C.H.,
RA Debuchy R., Wincker P., Weissenbach J., Silar P.;
RT "The genome sequence of the model ascomycete fungus Podospora anserina.";
RL Genome Biol. 9:R77.1-R77.22(2008).
RN [2] {ECO:0000313|EMBL:CAP72638.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=S mat+ {ECO:0000313|EMBL:CAP72638.1};
RA Genoscope - CEA;
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000001197}
RP GENOME REANNOTATION.
RC STRAIN=S / ATCC MYA-4624 / DSM 980 / FGSC 10383
RC {ECO:0000313|Proteomes:UP000001197};
RX PubMed=24558260; DOI=10.1534/genetics.113.159988;
RA Grognet P., Bidard F., Kuchly C., Tong L.C.H., Coppin E., Benkhali J.A.,
RA Couloux A., Wincker P., Debuchy R., Silar P.;
RT "Maintaining two mating types: Structure of the mating type locus and its
RT role in heterokaryosis in Podospora anserina.";
RL Genetics 197:421-432(2014).
RN [4] {ECO:0000313|EMBL:CDP25033.1}
RP NUCLEOTIDE SEQUENCE.
RA Grognet P., Bidard F., Kuchly C., Chan Ho Tong L., Coppin E.,
RA Ait Benkhali J., Couloux A., Wincker P., Debuchy R., Silar P.;
RT "Maintaining two mating types: Structure of the mating type locus and its
RT role in heterokaryosis in Podospora anserina.";
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the OSBP family.
CC {ECO:0000256|ARBA:ARBA00008842}.
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DR EMBL; CU640366; CAP72638.1; -; Genomic_DNA.
DR EMBL; FO904937; CDP25033.1; -; Genomic_DNA.
DR RefSeq; XP_001910813.1; XM_001910778.1.
DR AlphaFoldDB; B2B4B3; -.
DR STRING; 515849.B2B4B3; -.
DR GeneID; 6196521; -.
DR KEGG; pan:PODANSg7855; -.
DR VEuPathDB; FungiDB:PODANS_2_690; -.
DR eggNOG; KOG1737; Eukaryota.
DR HOGENOM; CLU_007105_4_0_1; -.
DR OrthoDB; 960at2759; -.
DR Proteomes; UP000001197; Chromosome 2.
DR GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR CDD; cd13289; PH_Osh3p_yeast; 1.
DR Gene3D; 2.40.160.120; -; 1.
DR Gene3D; 3.30.70.3490; -; 1.
DR Gene3D; 2.60.120.680; GOLD domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR036598; GOLD_dom_sf.
DR InterPro; IPR037239; OSBP_sf.
DR InterPro; IPR000648; Oxysterol-bd.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR041680; PH_8.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR10972:SF216; OXYSTEROL-BINDING PROTEIN HOMOLOG 3; 1.
DR PANTHER; PTHR10972; OXYSTEROL-BINDING PROTEIN-RELATED; 1.
DR Pfam; PF01237; Oxysterol_BP; 1.
DR Pfam; PF15409; PH_8; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF144000; Oxysterol-binding protein-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF101576; Supernatant protein factor (SPF), C-terminal domain; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 3: Inferred from homology;
KW Lipid transport {ECO:0000256|ARBA:ARBA00023055};
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Reference proteome {ECO:0000313|Proteomes:UP000001197};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 216..310
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 167..213
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 319..346
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 381..409
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 422..456
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 545..570
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 189..213
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 425..456
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 991 AA; 107791 MW; 0FF0AE1587981D62 CRC64;
MAGIEQLEIH SKAYIVRWVK VDVGHTISWS VQPHKKSINF GIVKHPGTGE TNLTSLADDA
GLADQHTECV AESKPGLFAK RDASTAQDQL AKKGFIPIHW HGKCEADKVS VGTYDVTQAG
MFGLVFDNTF SKQTSKTATF VLLTYPTGAP PQTARNLPNL QAGPLASASR TSLGKHGSPR
LGAAASESVD SLPSHTRGRA LSTATAAGKS ESGVSSSYHV GVLLKRRRKK GQGYAKRFFS
LDYTTCTLSY YHNRNSSALR GAIPLSLAAV AADERRREIT IDSGAEVWHL KASNAKEFSD
WARALERASK IARGVELPAT QPVSSESQGG VAPAPHITIP NSAQDEEREW RQVESLVSRM
VGTRDALRRL VKDMAVEKQP LSGHGYLSPS TPTLPEETEG YFGPPTTASA ADKKSFWKRK
ASGAASPLTP QSFQTAASSS LTIPASGHST PTQNGFKKQY GALQQEGPNT LENCTALLSD
LDSVVMEFST LLATSKRRRL PAQLSAQPRA SIESSTSTVD EFFDAEGGDA DRSTNQLMII
EHHSEDDTQA SDVEESIHES SSVSSIEDED DYAQNAEGGA NLFPPKPKSL IPLPITEPVT
RRKTIPPAKV APPSLIAFVR KNVGKDLSTI SMPVSANEPT SLLHRVSEQL EYAQLLDAAA
KHPDPKDRLL YMTAFAISGF SNTRAKERSI RKPFNPLLGE TFELVRSEAE VPGGFRLLVE
KVTHRPVRLA MQADSALWSF SQFPAPSQKF WGKSAEITTE GRVRVSLRLP DGTDEHYSWT
IATVFLRNVV MGEKYVEPVG SMNVNNDTTG AKAVIEFVAK GVFGGRGEEV KVETYGPNGS
KLGAGLAGTW TNGLKVVPGN KEIWKPGQLV ENAVNTYGMT TFAASLNEIT PIEKGKLPPT
DTRLRPDQRF AEQGDLDQAE EWKVKLEEAQ RVRRRVLEES GEEYKPKWFV KVAGGEGQAG
EEVWKLKGGK DGYWEERARG KWEGVVDIFA G
//
