GenomeNet

Database: UniProt
Entry: B2BKZ7_RAT
LinkDB: B2BKZ7_RAT
Original site: B2BKZ7_RAT 
ID   B2BKZ7_RAT              Unreviewed;       190 AA.
AC   B2BKZ7;
DT   20-MAY-2008, integrated into UniProtKB/TrEMBL.
DT   20-MAY-2008, sequence version 1.
DT   11-DEC-2019, entry version 84.
DE   SubName: Full=A030009H04Rik {ECO:0000313|EMBL:ABU49278.1};
DE   SubName: Full=Similar to RIKEN cDNA A030009H04 {ECO:0000313|Ensembl:ENSRNOP00000012061};
GN   Name=RGD1563441 {ECO:0000313|RGD:1563441};
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116 {ECO:0000313|EMBL:ABU49278.1};
RN   [1] {ECO:0000313|Ensembl:ENSRNOP00000012061, ECO:0000313|Proteomes:UP000002494}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000012061,
RC   ECO:0000313|Proteomes:UP000002494};
RX   PubMed=15057822; DOI=10.1038/nature02426;
RG   Rat Genome Sequencing Project Consortium;
RA   Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J.,
RA   Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G.,
RA   Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G.,
RA   Morgan M., Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G.,
RA   Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S.,
RA   Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T.,
RA   Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D.,
RA   Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L.,
RA   Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D.,
RA   Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M.,
RA   Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C.,
RA   Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J.,
RA   Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H.,
RA   Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X.,
RA   Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q.,
RA   Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P.,
RA   Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A.,
RA   Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C.,
RA   Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J.,
RA   Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J.,
RA   Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F.,
RA   Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A.,
RA   Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A.,
RA   Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J.,
RA   Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E.,
RA   Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M.,
RA   Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C.,
RA   Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L.,
RA   Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W.,
RA   Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y.,
RA   Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V.,
RA   Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M.,
RA   Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S.,
RA   Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B.,
RA   Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R.,
RA   Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J.,
RA   Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D.,
RA   Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S.,
RA   Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S.,
RA   Mockrin S., Collins F.S.;
RT   "Genome sequence of the Brown Norway rat yields insights into mammalian
RT   evolution.";
RL   Nature 428:493-521(2004).
RN   [2] {ECO:0000313|EMBL:ABU49278.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=BN {ECO:0000313|EMBL:ABU49279.1}, SHR
RC   {ECO:0000313|EMBL:ABU49281.1}, SHRSP {ECO:0000313|EMBL:ABU49282.1},
RC   and WHD {ECO:0000313|EMBL:ABU49278.1};
RX   PubMed=19710508; DOI=10.1095/biolreprod.109.078980;
RA   Liska F., Gosele C., Rivkin E., Tres L., Cardoso M.C., Domaing P.,
RA   Krejci E., Snajdr P., Lee-Kirsch M.A., Rooij D.G., Kren V., Krenova D.,
RA   Kierszenbaum A.L., Hubner N.;
RT   "Rat hd mutation reveals an essential role of centrobin in spermatid head
RT   shaping and assembly of the head-tail coupling apparatus.";
RL   Biol. Reprod. 81:1196-1205(2009).
RN   [3] {ECO:0000313|Ensembl:ENSRNOP00000012061}
RP   IDENTIFICATION.
RC   STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000012061};
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
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DR   EMBL; AABR07029856; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; EF532351; ABU49278.1; -; Genomic_DNA.
DR   EMBL; EF532352; ABU49279.1; -; Genomic_DNA.
DR   EMBL; EF532354; ABU49281.1; -; Genomic_DNA.
DR   EMBL; EF532355; ABU49282.1; -; Genomic_DNA.
DR   RefSeq; NP_001119764.1; NM_001126292.1.
DR   STRING; 10116.ENSRNOP00000012061; -.
DR   Ensembl; ENSRNOT00000012061; ENSRNOP00000012061; ENSRNOG00000021540.
DR   GeneID; 497935; -.
DR   KEGG; rno:497935; -.
DR   CTD; 284023; -.
DR   RGD; 1563441; RGD1563441.
DR   eggNOG; ENOG410JB4M; Eukaryota.
DR   eggNOG; ENOG41115JF; LUCA.
DR   GeneTree; ENSGT00390000002475; -.
DR   OMA; LDCNICY; -.
DR   OrthoDB; 1337075at2759; -.
DR   TreeFam; TF338347; -.
DR   Proteomes; UP000002494; Chromosome 10.
DR   Bgee; ENSRNOG00000021540; Expressed in 9 organ(s), highest expression level in brain.
DR   Gene3D; 3.30.40.10; -; 1.
DR   InterPro; IPR027952; DUF4632.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR017907; Znf_RING_CS.
DR   Pfam; PF15451; DUF4632; 1.
DR   Pfam; PF14634; zf-RING_5; 1.
DR   SMART; SM00184; RING; 1.
DR   PROSITE; PS00518; ZF_RING_1; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00175};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002494};
KW   Zinc {ECO:0000256|PROSITE-ProRule:PRU00175};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00175}.
FT   DOMAIN          18..81
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   REGION          107..145
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   190 AA;  20862 MW;  E2C5C41DF984B473 CRC64;
     MQLLMRVPSL PELGELDCNI CFRPYNLGAR APRRLPGTAR ARCGHTLCTA CLRELAARGD
     GSRTAARVVR LRRVVTCPFC RAPSPLPRGG ITEIALDPDL WSRLEEEAQA ECEGDPMGSP
     AKESGEDGED DDGEQESEMG AGPSSAGWRA LRRILDRVLA PARRLRRPLP SNVLYCPEVK
     DIAHMTRCTL
//
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