ID B2HGU2_MYCMM Unreviewed; 345 AA.
AC B2HGU2;
DT 10-JUN-2008, integrated into UniProtKB/TrEMBL.
DT 10-JUN-2008, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Polyprenyl synthetase IdsB_1 {ECO:0000313|EMBL:ACC41645.1};
GN Name=idsB_1 {ECO:0000313|EMBL:ACC41645.1};
GN OrderedLocusNames=MMAR_3219 {ECO:0000313|EMBL:ACC41645.1};
OS Mycobacterium marinum (strain ATCC BAA-535 / M).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium ulcerans group.
OX NCBI_TaxID=216594 {ECO:0000313|EMBL:ACC41645.1, ECO:0000313|Proteomes:UP000001190};
RN [1] {ECO:0000313|EMBL:ACC41645.1, ECO:0000313|Proteomes:UP000001190}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-535 / M {ECO:0000313|Proteomes:UP000001190};
RX PubMed=18403782; DOI=10.1101/gr.075069.107;
RA Stinear T.P., Seemann T., Harrison P.F., Jenkin G.A., Davies J.K.,
RA Johnson P.D., Abdellah Z., Arrowsmith C., Chillingworth T., Churcher C.,
RA Clarke K., Cronin A., Davis P., Goodhead I., Holroyd N., Jagels K.,
RA Lord A., Moule S., Mungall K., Norbertczak H., Quail M.A.,
RA Rabbinowitsch E., Walker D., White B., Whitehead S., Small P.L., Brosch R.,
RA Ramakrishnan L., Fischbach M.A., Parkhill J., Cole S.T.;
RT "Insights from the complete genome sequence of Mycobacterium marinum on the
RT evolution of Mycobacterium tuberculosis.";
RL Genome Res. 18:729-741(2008).
CC -!- PATHWAY: Isoprenoid biosynthesis. {ECO:0000256|ARBA:ARBA00005128}.
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|ARBA:ARBA00006706, ECO:0000256|RuleBase:RU004466}.
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DR EMBL; CP000854; ACC41645.1; -; Genomic_DNA.
DR RefSeq; WP_012394882.1; NC_010612.1.
DR AlphaFoldDB; B2HGU2; -.
DR STRING; 216594.MMAR_3219; -.
DR KEGG; mmi:MMAR_3219; -.
DR eggNOG; COG0142; Bacteria.
DR HOGENOM; CLU_014015_2_1_11; -.
DR OrthoDB; 4497239at2; -.
DR Proteomes; UP000001190; Chromosome.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR PANTHER; PTHR12001; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR12001:SF69; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SFLD; SFLDG01017; Polyprenyl_Transferase_Like; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
DR PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE 3: Inferred from homology;
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00022516};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000001190};
KW Transferase {ECO:0000256|RuleBase:RU004466}.
SQ SEQUENCE 345 AA; 35938 MW; C8EDC56ECA2744E5 CRC64;
MSLGMVNVAN ATPNAARVLL KNARQECDPV LRTAVGWLSE PLAKMAGYHL GWWDVNGVPV
DGSSGKSIRA ALAFGAASAC GDARAAAPVA AAVELMHNFS LVHDDVMDRD ATRRGRATVW
AVWGETNAIV LGDALHALAG RVLVEMLEPE VAANAVMRLE SSCVTLCDGQ FEDCDFETRE
SVSVDGYLEM AAGKTAGLMG CACALGALAA NADPATVTAM HQFGFQLGLA FQIVDDVMGL
WGDPNVTGKP VGSDLARRKK TFPVVAALGS GSEAAASLAQ LYGAKEPMSA DDVRQAIDLV
ETAGGRKAAE RQADECIGAA LAALPDSARS EDLIALTQLV IARDR
//
