ID   B2HM89_MYCMM            Unreviewed;       252 AA.
AC   B2HM89;
DT   10-JUN-2008, integrated into UniProtKB/TrEMBL.
DT   10-JUN-2008, sequence version 1.
DT   27-MAR-2024, entry version 61.
DE   RecName: Full=Thioesterase TesA {ECO:0000256|ARBA:ARBA00015007};
GN   OrderedLocusNames=MMAR_3693 {ECO:0000313|EMBL:ACC42109.1};
OS   Mycobacterium marinum (strain ATCC BAA-535 / M).
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium ulcerans group.
OX   NCBI_TaxID=216594 {ECO:0000313|EMBL:ACC42109.1, ECO:0000313|Proteomes:UP000001190};
RN   [1] {ECO:0000313|EMBL:ACC42109.1, ECO:0000313|Proteomes:UP000001190}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-535 / M {ECO:0000313|Proteomes:UP000001190};
RX   PubMed=18403782; DOI=10.1101/gr.075069.107;
RA   Stinear T.P., Seemann T., Harrison P.F., Jenkin G.A., Davies J.K.,
RA   Johnson P.D., Abdellah Z., Arrowsmith C., Chillingworth T., Churcher C.,
RA   Clarke K., Cronin A., Davis P., Goodhead I., Holroyd N., Jagels K.,
RA   Lord A., Moule S., Mungall K., Norbertczak H., Quail M.A.,
RA   Rabbinowitsch E., Walker D., White B., Whitehead S., Small P.L., Brosch R.,
RA   Ramakrishnan L., Fischbach M.A., Parkhill J., Cole S.T.;
RT   "Insights from the complete genome sequence of Mycobacterium marinum on the
RT   evolution of Mycobacterium tuberculosis.";
RL   Genome Res. 18:729-741(2008).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a fatty acyl-CoA + H2O = a fatty acid + CoA + H(+);
CC         Xref=Rhea:RHEA:16781, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:28868, ChEBI:CHEBI:57287, ChEBI:CHEBI:77636;
CC         Evidence={ECO:0000256|ARBA:ARBA00024293};
CC   -!- SIMILARITY: Belongs to the thioesterase family.
CC       {ECO:0000256|ARBA:ARBA00007169}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000854; ACC42109.1; -; Genomic_DNA.
DR   RefSeq; WP_012395308.1; NC_010612.1.
DR   AlphaFoldDB; B2HM89; -.
DR   STRING; 216594.MMAR_3693; -.
DR   GeneID; 34341919; -.
DR   KEGG; mmi:MMAR_3693; -.
DR   eggNOG; COG3208; Bacteria.
DR   HOGENOM; CLU_070456_1_2_11; -.
DR   OrthoDB; 8480037at2; -.
DR   Proteomes; UP000001190; Chromosome.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR012223; TEII.
DR   InterPro; IPR001031; Thioesterase.
DR   PANTHER; PTHR11487:SF0; S-ACYL FATTY ACID SYNTHASE THIOESTERASE, MEDIUM CHAIN; 1.
DR   PANTHER; PTHR11487; THIOESTERASE; 1.
DR   Pfam; PF00975; Thioesterase; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001190}.
FT   DOMAIN          21..241
FT                   /note="Thioesterase"
FT                   /evidence="ECO:0000259|Pfam:PF00975"
SQ   SEQUENCE   252 AA;  27098 MW;  D18BCB8BB82C449A CRC64;
     MARKLGWVRQ FHEPDAPESL PLLVFPHAGA GASAYREFSK VLSETFNVIV FQYPGRQDRA
     AEPSCAAISE IAAGAFSEFA ASEHNRGLPI ITFGHSMGAL VAFEFVRLAE ANGIDVRHLN
     VSAAVAPCNA AAKPAHPSDD EEILNHLGAL EGTDTDVFSN RELMRLALPV IKADYHAFDT
     YSCAEDIKVA TPIHAMGGDQ DPYITLGDLY GWGKHTDTAK VTMFDGGHFY LRSHIDAVAA
     LLASSAQCGQ QA
//