ID B2HSL8_MYCMM Unreviewed; 197 AA.
AC B2HSL8;
DT 10-JUN-2008, integrated into UniProtKB/TrEMBL.
DT 10-JUN-2008, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE SubName: Full=Transcriptional regulator {ECO:0000313|EMBL:ACC39476.1};
GN OrderedLocusNames=MMAR_1019 {ECO:0000313|EMBL:ACC39476.1};
OS Mycobacterium marinum (strain ATCC BAA-535 / M).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium ulcerans group.
OX NCBI_TaxID=216594 {ECO:0000313|EMBL:ACC39476.1, ECO:0000313|Proteomes:UP000001190};
RN [1] {ECO:0000313|EMBL:ACC39476.1, ECO:0000313|Proteomes:UP000001190}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-535 / M {ECO:0000313|Proteomes:UP000001190};
RX PubMed=18403782; DOI=10.1101/gr.075069.107;
RA Stinear T.P., Seemann T., Harrison P.F., Jenkin G.A., Davies J.K.,
RA Johnson P.D., Abdellah Z., Arrowsmith C., Chillingworth T., Churcher C.,
RA Clarke K., Cronin A., Davis P., Goodhead I., Holroyd N., Jagels K.,
RA Lord A., Moule S., Mungall K., Norbertczak H., Quail M.A.,
RA Rabbinowitsch E., Walker D., White B., Whitehead S., Small P.L., Brosch R.,
RA Ramakrishnan L., Fischbach M.A., Parkhill J., Cole S.T.;
RT "Insights from the complete genome sequence of Mycobacterium marinum on the
RT evolution of Mycobacterium tuberculosis.";
RL Genome Res. 18:729-741(2008).
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DR EMBL; CP000854; ACC39476.1; -; Genomic_DNA.
DR RefSeq; WP_011739041.1; NC_010612.1.
DR AlphaFoldDB; B2HSL8; -.
DR STRING; 216594.MMAR_1019; -.
DR GeneID; 72436015; -.
DR KEGG; mmi:MMAR_1019; -.
DR eggNOG; COG1309; Bacteria.
DR HOGENOM; CLU_069356_2_1_11; -.
DR OrthoDB; 956698at2; -.
DR Proteomes; UP000001190; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProt.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR041347; MftR_C.
DR InterPro; IPR023851; Tscrpt_reg_TetR-type.
DR NCBIfam; TIGR03968; mycofact_TetR; 1.
DR PANTHER; PTHR30055; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR PANTHER; PTHR30055:SF164; TRANSCRIPTIONAL REPRESSOR MCE3R; 1.
DR Pfam; PF17754; TetR_C_14; 1.
DR Pfam; PF00440; TetR_N; 1.
DR PRINTS; PR00455; HTHTETR.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335};
KW Reference proteome {ECO:0000313|Proteomes:UP000001190};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 12..72
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 35..54
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
SQ SEQUENCE 197 AA; 21987 MW; 953E7778B84CB0CB CRC64;
MAHESRAGRR PSTTKRHIAD VAIDLFAART FAEVSVDDVA QAAGIARRTL FRYYASKNAI
PWGDFDTHLA QLQDLLERID GHVRLGKALR EALLAFNTYD ESETIRHRQR MRIILQTAEL
QAYSMTMYAG WRAVIAGFVA RRLSVKPTDL VPQTVAWTML GVALSAYEHW LSDESVSLPE
ALGNAFDVVG AGLEKLD
//
