ID B2IBA2_BEII9 Unreviewed; 513 AA.
AC B2IBA2;
DT 10-JUN-2008, integrated into UniProtKB/TrEMBL.
DT 10-JUN-2008, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Thiamine pyrophosphate protein domain protein TPP-binding {ECO:0000313|EMBL:ACB95186.1};
GN OrderedLocusNames=Bind_1554 {ECO:0000313|EMBL:ACB95186.1};
OS Beijerinckia indica subsp. indica (strain ATCC 9039 / DSM 1715 / NCIMB
OS 8712).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Beijerinckiaceae; Beijerinckia.
OX NCBI_TaxID=395963 {ECO:0000313|EMBL:ACB95186.1, ECO:0000313|Proteomes:UP000001695};
RN [1] {ECO:0000313|Proteomes:UP000001695}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 9039 / DSM 1715 / NCIMB 8712
RC {ECO:0000313|Proteomes:UP000001695};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., LaButti K., Schmutz J., Larimer F.,
RA Land M., Hauser L., Kyrpides N., Mikhailova N., Dunfield P.F., Dedysh S.N.,
RA Liesack W., Saw J.H., Alam M., Chen Y., Murrell J.C., Richardson P.;
RT "Complete sequence of chromosome of Beijerinckia indica subsp. indica ATCC
RT 9039.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACB95186.1, ECO:0000313|Proteomes:UP000001695}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 9039 / DSM 1715 / NCIMB 8712
RC {ECO:0000313|Proteomes:UP000001695};
RX PubMed=20601475; DOI=10.1128/JB.00656-10;
RA Tamas I., Dedysh S.N., Liesack W., Stott M.B., Alam M., Murrell J.C.,
RA Dunfield P.F.;
RT "Complete genome sequence of Beijerinckia indica subsp. indica.";
RL J. Bacteriol. 192:4532-4533(2010).
CC -!- SIMILARITY: Belongs to the TPP enzyme family.
CC {ECO:0000256|ARBA:ARBA00007812}.
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DR EMBL; CP001016; ACB95186.1; -; Genomic_DNA.
DR RefSeq; WP_012384543.1; NC_010581.1.
DR AlphaFoldDB; B2IBA2; -.
DR STRING; 395963.Bind_1554; -.
DR KEGG; bid:Bind_1554; -.
DR eggNOG; COG0028; Bacteria.
DR HOGENOM; CLU_013748_8_0_5; -.
DR OrthoDB; 9773408at2; -.
DR Proteomes; UP000001695; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR CDD; cd02002; TPP_BFDC; 1.
DR CDD; cd07035; TPP_PYR_POX_like; 1.
DR Gene3D; 3.40.50.970; -; 2.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR012001; Thiamin_PyroP_enz_TPP-bd_dom.
DR InterPro; IPR045229; TPP_enz.
DR InterPro; IPR011766; TPP_enzyme_TPP-bd.
DR PANTHER; PTHR18968:SF86; ACETOLACTATE SYNTHASE LARGE SUBUNIT ILVX-RELATED; 1.
DR PANTHER; PTHR18968; THIAMINE PYROPHOSPHATE ENZYMES; 1.
DR Pfam; PF02775; TPP_enzyme_C; 1.
DR Pfam; PF02776; TPP_enzyme_N; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001695}.
FT DOMAIN 1..106
FT /note="Thiamine pyrophosphate enzyme N-terminal TPP-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02776"
FT DOMAIN 383..511
FT /note="Thiamine pyrophosphate enzyme TPP-binding"
FT /evidence="ECO:0000259|Pfam:PF02775"
SQ SEQUENCE 513 AA; 53979 MW; A62220BAD68138E4 CRC64;
MNGAESLLRT LVASGIEVCF ANPGTSEMHF VSALDRIEGI RPVLTLFEGV ATGAADGYAR
MAEKPAATLL HLGPGLANGL ANLHNARKAQ TPMVNIIGDH ATTHQRFETP LTSNVAALAQ
PVSHWVATCR GPKTVAADAA RAVQAARVAP GQIASLILPA DTAWQPAERA ASPLPVMGPA
PVSDQAITQA RDALLLGNAA LLLRGTALRG RGLRAAGRIA AATGARLLCD TFTPRIERGA
GRVHVERLPY RPAPTMACLQ GTRTLILVGT QAPVAFFAYP DQPSALTPPD CDVLVFSHPH
EDAAEGLEQL AEAIGAGDYA PISPCKPPEL PIEGGLDPES VMRIIGHYLP EDAIISDESL
TSGFLPYPLL DTALPHDHLH LAGGAIGDGL PVAVGAAIAC PGRKVIALQA DGSAMYTLQS
LWTQAREQLD ITTIIYANRA YKVLFEELHS VGAAKAGPHA FSLFDLHDPT LNWVKLAEGM
GVEARRVEDT RNLTSALRSA ITGRGPRLIE VVL
//
