ID B2IXG2_NOSP7 Unreviewed; 408 AA.
AC B2IXG2;
DT 10-JUN-2008, integrated into UniProtKB/TrEMBL.
DT 10-JUN-2008, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Tyrosinase {ECO:0000313|EMBL:ACC79984.1};
DE EC=1.14.18.1 {ECO:0000313|EMBL:ACC79984.1};
GN OrderedLocusNames=Npun_R1263 {ECO:0000313|EMBL:ACC79984.1};
OS Nostoc punctiforme (strain ATCC 29133 / PCC 73102).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae; Nostoc.
OX NCBI_TaxID=63737 {ECO:0000313|EMBL:ACC79984.1, ECO:0000313|Proteomes:UP000001191};
RN [1] {ECO:0000313|Proteomes:UP000001191}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29133 / PCC 73102 {ECO:0000313|Proteomes:UP000001191};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Meeks J.C., Elhai J.,
RA Campbell E.L., Thiel T., Longmire J., Potts M., Atlas R.;
RT "Complete sequence of chromosome of Nostoc punctiforme ATCC 29133.";
RL Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACC79984.1, ECO:0000313|Proteomes:UP000001191}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29133 / PCC 73102 {ECO:0000313|Proteomes:UP000001191};
RX PubMed=23463784; DOI=10.1104/pp.112.213116;
RA Ekman M., Picossi S., Campbell E.L., Meeks J.C., Flores E.;
RT "A Nostoc punctiforme Sugar Transporter Necessary to Establish a
RT Cyanobacterium-Plant Symbiosis.";
RL Plant Physiol. 161:1984-1992(2013).
CC -!- COFACTOR:
CC Name=Cu(2+); Xref=ChEBI:CHEBI:29036;
CC Evidence={ECO:0000256|ARBA:ARBA00001973};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP001037; ACC79984.1; -; Genomic_DNA.
DR RefSeq; WP_012408005.1; NC_010628.1.
DR AlphaFoldDB; B2IXG2; -.
DR STRING; 63737.Npun_R1263; -.
DR EnsemblBacteria; ACC79984; ACC79984; Npun_R1263.
DR KEGG; npu:Npun_R1263; -.
DR eggNOG; COG2304; Bacteria.
DR HOGENOM; CLU_035914_3_0_3; -.
DR OrthoDB; 2874181at2; -.
DR Proteomes; UP000001191; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004503; F:tyrosinase activity; IEA:UniProtKB-EC.
DR Gene3D; 1.10.1280.10; Di-copper center containing domain from catechol oxidase; 1.
DR InterPro; IPR008922; Di-copper_centre_dom_sf.
DR InterPro; IPR002227; Tyrosinase_Cu-bd.
DR PANTHER; PTHR11474:SF124; TYROSINASE; 1.
DR PANTHER; PTHR11474; TYROSINASE FAMILY MEMBER; 1.
DR Pfam; PF00264; Tyrosinase; 1.
DR PRINTS; PR00092; TYROSINASE.
DR SUPFAM; SSF48056; Di-copper centre-containing domain; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR PROSITE; PS00498; TYROSINASE_2; 1.
PE 4: Predicted;
KW Copper {ECO:0000256|ARBA:ARBA00023008};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000313|EMBL:ACC79984.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001191}.
FT DOMAIN 310..321
FT /note="Tyrosinase copper-binding"
FT /evidence="ECO:0000259|PROSITE:PS00498"
SQ SEQUENCE 408 AA; 45464 MW; 55A3C44F50741BD5 CRC64;
MKLLLKSVKI LIYSLLIVSA CAVTVFAHDR IGYGQDKHYR YENLRGQYAQ LAVRKNVTDL
TPAEKAAFVK AIKTLKTTIP AGSKVSIYDQ FVAIHLGATR LIHNHKGHSD GSVQELAHEN
AAFFPWHREY IRRFEQALQA VNRTVTLPYW DWTDPKAFDV IFNDDFLGSN GQGVTIKIPN
QGDFTGGAVQ TGAFAAANGW IMNPELNLDP DTGTSLGTSL VRFLKIPPAT DYPVPKKDIE
RALSLNNYSL FRPALEGFIS VDEQGKVTPG GFIHNYIHGL VGGAQIDAST TPVTFKGLGT
MSNIPSSPYD PVFWLHHANV DRLWAEWQEN GHKGSDFYPA DGQPYGHNLK DLMWPWDGGM
STPKATALGN LLSLLPKFNP SDLVRPIDVL NHKELGYTYE TWERKTQR
//
