ID B2JEG0_PARP8 Unreviewed; 425 AA.
AC B2JEG0;
DT 10-JUN-2008, integrated into UniProtKB/TrEMBL.
DT 10-JUN-2008, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=Efflux transporter, RND family, MFP subunit {ECO:0000313|EMBL:ACC69837.1};
DE Flags: Precursor;
GN OrderedLocusNames=Bphy_0647 {ECO:0000313|EMBL:ACC69837.1};
OS Paraburkholderia phymatum (strain DSM 17167 / CIP 108236 / LMG 21445 /
OS STM815) (Burkholderia phymatum).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Paraburkholderia.
OX NCBI_TaxID=391038 {ECO:0000313|EMBL:ACC69837.1, ECO:0000313|Proteomes:UP000001192};
RN [1] {ECO:0000313|Proteomes:UP000001192}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17167 / CIP 108236 / LMG 21445 / STM815
RC {ECO:0000313|Proteomes:UP000001192};
RX PubMed=25197461; DOI=10.4056/sigs.4861021;
RA Moulin L., Klonowska A., Caroline B., Booth K., Vriezen J.A., Melkonian R.,
RA James E.K., Young J.P., Bena G., Hauser L., Land M., Kyrpides N., Bruce D.,
RA Chain P., Copeland A., Pitluck S., Woyke T., Lizotte-Waniewski M.,
RA Bristow J., Riley M.;
RT "Complete genome sequence of Burkholderia phymatum STM815(T), a broad host
RT range and efficient nitrogen-fixing symbiont of Mimosa species.";
RL Stand. Genomic Sci. 9:763-774(2014).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; CP001043; ACC69837.1; -; Genomic_DNA.
DR RefSeq; WP_012400058.1; NC_010622.1.
DR AlphaFoldDB; B2JEG0; -.
DR STRING; 391038.Bphy_0647; -.
DR KEGG; bph:Bphy_0647; -.
DR eggNOG; COG0845; Bacteria.
DR HOGENOM; CLU_018816_2_1_4; -.
DR OrthoDB; 9783047at2; -.
DR Proteomes; UP000001192; Chromosome 1.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30158; ACRA/E-RELATED COMPONENT OF DRUG EFFLUX TRANSPORTER; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001192};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..425
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002779268"
FT DOMAIN 69..303
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT REGION 387..411
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 425 AA; 45786 MW; 3B16BAE960C8DF0C CRC64;
MGWTFRHPSI LAAWPLASRF ALAAALVSAL SLTACKKAPT EPPRPTVEVT VVTVAQKETP
VDFEFTAQTQ SSREVEIRAR VDGFLERRLY DEGALVKEGQ VLFVIDRKPF EAALQSARGV
LAQQQARLLV TRQNLARVVP LAAQNALSKK DLDDATGNEK EAEAAVIAAQ GEVRTAELNL
SYCTIRSPLK GLSSFARVQD GSYVTPTQSG LLTYVYQLDP MWVNFSISEN ELLRYREQIA
KGLLRFPADN RFDVTVIQAD GSVYPQKGRI DFTNPAFSQQ TGTFLVRATF ANPDGTLRPG
QFVRAKVSGA VRPNAILVPQ RAVLQGAKSH FVWVLDQDAK PHQRVVDVGD WHGDDWFVNE
GLKPGERVVV DGAIRVSSDA QIKVVSAPPG SGAPGTPAAP ASAPAAAASV PVATVAGTQA
RPASP
//
