ID B2U6S4_RALPJ Unreviewed; 407 AA.
AC B2U6S4;
DT 01-JUL-2008, integrated into UniProtKB/TrEMBL.
DT 01-JUL-2008, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE SubName: Full=Integrase family protein {ECO:0000313|EMBL:ACD27206.1};
GN OrderedLocusNames=Rpic_2072 {ECO:0000313|EMBL:ACD27206.1};
OS Ralstonia pickettii (strain 12J).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Ralstonia.
OX NCBI_TaxID=402626 {ECO:0000313|EMBL:ACD27206.1};
RN [1] {ECO:0000313|EMBL:ACD27206.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=12J {ECO:0000313|EMBL:ACD27206.1};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Meincke L., Brettin T., Detter J.C.,
RA Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L.,
RA Kyrpides N., Mikhailova N., Marsh T., Richardson P.;
RT "Complete sequence of chromosome1 of Ralstonia pickettii 12J.";
RL Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the 'phage' integrase family.
CC {ECO:0000256|ARBA:ARBA00008857}.
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DR EMBL; CP001068; ACD27206.1; -; Genomic_DNA.
DR AlphaFoldDB; B2U6S4; -.
DR STRING; 402626.Rpic_2072; -.
DR KEGG; rpi:Rpic_2072; -.
DR PATRIC; fig|402626.5.peg.3221; -.
DR eggNOG; COG0582; Bacteria.
DR HOGENOM; CLU_027562_0_0_4; -.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0075713; P:establishment of integrated proviral latency; IEA:UniProtKB-KW.
DR GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR GO; GO:0044826; P:viral genome integration into host DNA; IEA:UniProtKB-KW.
DR CDD; cd00801; INT_P4_C; 1.
DR Gene3D; 1.10.150.130; -; 1.
DR Gene3D; 3.30.160.390; Integrase, DNA-binding domain; 1.
DR Gene3D; 1.10.443.10; Intergrase catalytic core; 1.
DR InterPro; IPR044068; CB.
DR InterPro; IPR011010; DNA_brk_join_enz.
DR InterPro; IPR013762; Integrase-like_cat_sf.
DR InterPro; IPR002104; Integrase_catalytic.
DR InterPro; IPR038488; Integrase_DNA-bd_sf.
DR InterPro; IPR025166; Integrase_DNA_bind_dom.
DR InterPro; IPR010998; Integrase_recombinase_N.
DR PANTHER; PTHR30629; PROPHAGE INTEGRASE; 1.
DR PANTHER; PTHR30629:SF2; PROPHAGE INTEGRASE INTS-RELATED; 1.
DR Pfam; PF13356; Arm-DNA-bind_3; 1.
DR Pfam; PF00589; Phage_integrase; 1.
DR SUPFAM; SSF56349; DNA breaking-rejoining enzymes; 1.
DR PROSITE; PS51900; CB; 1.
DR PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE 3: Inferred from homology;
KW DNA integration {ECO:0000256|ARBA:ARBA00022908};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU01248};
KW Viral genome integration {ECO:0000256|ARBA:ARBA00023195};
KW Virus entry into host cell {ECO:0000256|ARBA:ARBA00023296}.
FT DOMAIN 98..179
FT /note="Core-binding (CB)"
FT /evidence="ECO:0000259|PROSITE:PS51900"
FT DOMAIN 203..381
FT /note="Tyr recombinase"
FT /evidence="ECO:0000259|PROSITE:PS51898"
FT REGION 186..206
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 407 AA; 44949 MW; C65223DCC4F989CD CRC64;
MALTDTAVRN ARPAEKPIKL FDGGGLFLHI TPGGQRYWRL KYRFAGKEKL LALGVYPEVG
LKEARDRREE AKRLLGEGVD PSVERKVRKV ATVERAANSF EAVAREWHTK YAPGWSKSNA
DKVIARLQND VFPWLGGRPI AELKAPDLLA VCRRVESRGA LDTAHRVLQT CGQIFRYAVA
TGRAERDPSG DLRGALPPAK GKHYAAPTDP KEVAGLLRVF DGFTGTFVVK CALLLAPMLF
VRPGELRAAE WADIDLDAGE WRFVSSKRDV AHIVPLSTQA VAILRDLHAL TGHGHYVFPG
ARDKKKPMSE AAINAALKRM GIDTQKEFTG HGVRPIARTI LREVLGFEAE VIELQLAHRK
KDPNGAAYDR VAFLAVRKQM MQAWADYLDR LKTGAAVVPM PTSRTAA
//
