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Database: UniProt
Entry: B2UA08_RALPJ
LinkDB: B2UA08_RALPJ
Original site: B2UA08_RALPJ 
ID   B2UA08_RALPJ            Unreviewed;       215 AA.
AC   B2UA08;
DT   01-JUL-2008, integrated into UniProtKB/TrEMBL.
DT   01-JUL-2008, sequence version 1.
DT   27-MAR-2024, entry version 99.
DE   SubName: Full=RNA polymerase, sigma-24 subunit, ECF subfamily {ECO:0000313|EMBL:ACD27702.1};
GN   OrderedLocusNames=Rpic_2575 {ECO:0000313|EMBL:ACD27702.1};
OS   Ralstonia pickettii (strain 12J).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Ralstonia.
OX   NCBI_TaxID=402626 {ECO:0000313|EMBL:ACD27702.1};
RN   [1] {ECO:0000313|EMBL:ACD27702.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=12J {ECO:0000313|EMBL:ACD27702.1};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Meincke L., Brettin T., Detter J.C.,
RA   Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L.,
RA   Kyrpides N., Mikhailova N., Marsh T., Richardson P.;
RT   "Complete sequence of chromosome1 of Ralstonia pickettii 12J.";
RL   Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the sigma-70 factor family. ECF subfamily.
CC       {ECO:0000256|ARBA:ARBA00010641}.
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DR   EMBL; CP001068; ACD27702.1; -; Genomic_DNA.
DR   AlphaFoldDB; B2UA08; -.
DR   STRING; 402626.Rpic_2575; -.
DR   KEGG; rpi:Rpic_2575; -.
DR   eggNOG; COG1595; Bacteria.
DR   HOGENOM; CLU_047691_9_3_4; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR   CDD; cd06171; Sigma70_r4; 1.
DR   Gene3D; 1.10.1740.10; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR039425; RNA_pol_sigma-70-like.
DR   InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR   InterPro; IPR007627; RNA_pol_sigma70_r2.
DR   InterPro; IPR007630; RNA_pol_sigma70_r4.
DR   InterPro; IPR013325; RNA_pol_sigma_r2.
DR   InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   NCBIfam; TIGR02937; sigma70-ECF; 1.
DR   PANTHER; PTHR43133:SF57; BLR2203 PROTEIN; 1.
DR   PANTHER; PTHR43133; RNA POLYMERASE ECF-TYPE SIGMA FACTO; 1.
DR   Pfam; PF04542; Sigma70_r2; 1.
DR   Pfam; PF04545; Sigma70_r4; 1.
DR   SUPFAM; SSF88946; Sigma2 domain of RNA polymerase sigma factors; 1.
DR   SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Sigma factor {ECO:0000256|ARBA:ARBA00023082};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          53..120
FT                   /note="RNA polymerase sigma-70 region 2"
FT                   /evidence="ECO:0000259|Pfam:PF04542"
FT   DOMAIN          161..210
FT                   /note="RNA polymerase sigma-70 region 4"
FT                   /evidence="ECO:0000259|Pfam:PF04545"
FT   REGION          1..29
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   215 AA;  23905 MW;  42FA09BA15F9A89C CRC64;
     MLTYQRTAED PAAQPADPPA TSAAARPPSA DAEELAALLQ RISLGDRDAL RTLYTRCAPK
     LFGLALRILV RKDWAEDVLQ ESFVNIWRHA GDYRPHLAAP MTWMTTIVRN RALDCLRRQH
     AERVQESVPL DEAYADVLAD HAPGPADIAL AGQQARALAE CLKRLDPKQR QVVSLAYLRD
     LSHSELAQTL SLPLGTVKSW MRRGLDRLRE CLGAP
//
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