ID B2UIB3_RALPJ Unreviewed; 916 AA.
AC B2UIB3;
DT 01-JUL-2008, integrated into UniProtKB/TrEMBL.
DT 01-JUL-2008, sequence version 1.
DT 27-MAR-2024, entry version 103.
DE SubName: Full=Diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(S) {ECO:0000313|EMBL:ACD29314.1};
GN OrderedLocusNames=Rpic_4217 {ECO:0000313|EMBL:ACD29314.1};
OS Ralstonia pickettii (strain 12J).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Ralstonia.
OX NCBI_TaxID=402626 {ECO:0000313|EMBL:ACD29314.1};
RN [1] {ECO:0000313|EMBL:ACD29314.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=12J {ECO:0000313|EMBL:ACD29314.1};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Meincke L., Brettin T., Detter J.C.,
RA Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L.,
RA Kyrpides N., Mikhailova N., Marsh T., Richardson P.;
RT "Complete sequence of chromosome2 of Ralstonia pickettii 12J.";
RL Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP001069; ACD29314.1; -; Genomic_DNA.
DR AlphaFoldDB; B2UIB3; -.
DR STRING; 402626.Rpic_4217; -.
DR KEGG; rpi:Rpic_4217; -.
DR PATRIC; fig|402626.5.peg.469; -.
DR eggNOG; COG2203; Bacteria.
DR eggNOG; COG5001; Bacteria.
DR HOGENOM; CLU_000445_70_34_4; -.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR012226; Diguanyl_cyclase/Pdiesterase.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF13185; GAF_2; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00989; PAS; 2.
DR PIRSF; PIRSF005925; Dos; 2.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
FT DOMAIN 44..108
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 343..391
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 423..476
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 508..641
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 650..904
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 916 AA; 99031 MW; 6C3B228D5CA37055 CRC64;
MTQFLPAQAG ASPADVAPSP EAAQRPVAVT AGAMAEGRNT DFDALSRLSS DAVLLTVDGR
LVQANPAAAR LLGAQDPAQL AGLQLAGLIH PDDVAQVVPR LAGMVSSGVS AQPVEHRLVR
ADYTHVLVAS EAAACEHEGQ PAVMLVLREA VSRHALERHA VQARAEALHA RRLLASENAV
LAQLASNATL STVLRHLCLY VEQVYPNAMS ALLLLDAGSQ TLRVAAAPTL PAAYAATLEN
SPVGPEAGAC GCAMYLGDTV FIDSIATDPR WQRERTAALA AGFASAWALP IRSSRGDKLG
VLALFYRQPC MPVEEEQHFL DDVTHLAGVA IQKDNVERGL AESEERYRLA ISNLHEGVVI
ISPDGVVQAA NASAERILRV RPGQLVGRNR LDPIQRVVDE YGKEIGSTMM PSGQVLRTGE
PIFGRVYGLL LKTGELMWVR QNIIPIRRHA EPTPSSVMLS FADITDIKRA EQRLRHLAAH
DALTGLTNRS FFIAHLESAI ESARDESREL ALFFLDLDRF KSVNDTAGHA CGDTLLQSAA
ARLTDCIGPG DVIARLGGDE FVILIDQRVE GKRIALLAER LLQAMREPFD TVNGRYYLGV
SIGVALYPHD GISGSDLLRS ADAAMYRAKQ NGRNRAQFYT AELNARLQRR YMLENALRDA
RENNELQLVY QPKYDLASHR IVGAEALLRW NSAKLGAISP VEFIPVAEET GLIVPIGAWV
LRRACEQAVI WYEALGYDFR MAVNLSARQF QAGDVVPMIE QTLADSGLPP TALEVEITES
LLMGGADEVR PMFDALTAQG IRISIDDFGT GYSSLSYLQR FPISNVKIDR SFITGIPHDP
DSVALTEAIV AMARALGMTV TAEGVEDADQ VEFLAKAGCQ EIQGYYIGKP VTAEGFDRLL
RAHLSVVDAG VRAALG
//
