ID B2UK24_RALPJ Unreviewed; 425 AA.
AC B2UK24;
DT 01-JUL-2008, integrated into UniProtKB/TrEMBL.
DT 01-JUL-2008, sequence version 1.
DT 27-MAR-2024, entry version 85.
DE RecName: Full=Poly-beta-1,6-N-acetyl-D-glucosamine synthase {ECO:0000256|ARBA:ARBA00017381, ECO:0000256|RuleBase:RU364028};
DE Short=Poly-beta-1,6-GlcNAc synthase {ECO:0000256|RuleBase:RU364028};
DE EC=2.4.1.- {ECO:0000256|RuleBase:RU364028};
GN OrderedLocusNames=Rpic_4841 {ECO:0000313|EMBL:ACD29925.1};
OS Ralstonia pickettii (strain 12J).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Ralstonia.
OX NCBI_TaxID=402626 {ECO:0000313|EMBL:ACD29925.1};
RN [1] {ECO:0000313|EMBL:ACD29925.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=12J {ECO:0000313|EMBL:ACD29925.1};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Meincke L., Brettin T., Detter J.C.,
RA Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L.,
RA Kyrpides N., Mikhailova N., Marsh T., Richardson P.;
RT "Complete sequence of chromosome2 of Ralstonia pickettii 12J.";
RL Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU364028};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU364028}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 2 family.
CC {ECO:0000256|ARBA:ARBA00006739, ECO:0000256|RuleBase:RU364028}.
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DR EMBL; CP001069; ACD29925.1; -; Genomic_DNA.
DR AlphaFoldDB; B2UK24; -.
DR STRING; 402626.Rpic_4841; -.
DR CAZy; GT2; Glycosyltransferase Family 2.
DR KEGG; rpi:Rpic_4841; -.
DR PATRIC; fig|402626.5.peg.1087; -.
DR eggNOG; COG1215; Bacteria.
DR HOGENOM; CLU_023978_0_1_4; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008375; F:acetylglucosaminyltransferase activity; IEA:InterPro.
DR GO; GO:0043708; P:cell adhesion involved in biofilm formation; IEA:InterPro.
DR CDD; cd06423; CESA_like; 1.
DR InterPro; IPR001173; Glyco_trans_2-like.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR InterPro; IPR023853; PGA_PgaC/IcaA.
DR NCBIfam; TIGR03937; PgaC_IcaA; 1.
DR PANTHER; PTHR43630; POLY-BETA-1,6-N-ACETYL-D-GLUCOSAMINE SYNTHASE; 1.
DR PANTHER; PTHR43630:SF1; POLY-BETA-1,6-N-ACETYL-D-GLUCOSAMINE SYNTHASE; 1.
DR Pfam; PF00535; Glycos_transf_2; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|RuleBase:RU364028};
KW Glycosyltransferase {ECO:0000256|RuleBase:RU364028};
KW Membrane {ECO:0000256|RuleBase:RU364028};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU364028};
KW Transmembrane {ECO:0000256|RuleBase:RU364028};
KW Transmembrane helix {ECO:0000256|RuleBase:RU364028}.
FT TRANSMEM 15..36
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364028"
FT TRANSMEM 307..329
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364028"
FT TRANSMEM 341..359
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364028"
FT TRANSMEM 379..402
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364028"
FT DOMAIN 59..226
FT /note="Glycosyltransferase 2-like"
FT /evidence="ECO:0000259|Pfam:PF00535"
SQ SEQUENCE 425 AA; 49037 MW; 74B3CF5FC76F0716 CRC64;
MDPLLAKRWI SGFVFYYPFF MSYFWMIGGL LHYFLLERGT RRIQHPLALL GVKTYPKVSI
IVPCYNEEAN VREVISHLAR MRYPNYDIIA VNDGSSDRTG ERLNELAAQY PQLVVIHQSS
NQGKAIGLTT AAQVTDAEYL MCIDGDSILD VDAIAWMIRH LMENPAVGAV TGNPRIRTRS
TLLGRMQVGE FSSIVGLIKR TQQVYGRLLT VSGVVVMFRK RAIEEVGYWS NDMLTEDIDI
SWKLQVGGWT IRYEPRALSW ILMPETFRGL YKQRLRWAKG GIQALIKYAP AMLSLRQSMM
WPIFFEYALS VVWAYNMLLV ITWSVLGLFV DMPPEWRMEA FPRWHGTLLF ITCVLQLLIG
CFIDRRYDDG ILRYFIDTVW YPVAFWILNL VTTVIGFPAV AFQRQRARAR WTSPDRGIQQ
QGNSP
//
