ID B2UKX0_AKKM8 Unreviewed; 649 AA.
AC B2UKX0;
DT 01-JUL-2008, integrated into UniProtKB/TrEMBL.
DT 01-JUL-2008, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=Glycoside hydrolase family 97 protein {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=Amuc_1420 {ECO:0000313|EMBL:ACD05243.1};
OS Akkermansia muciniphila (strain ATCC BAA-835 / DSM 22959 / JCM 33894 / BCRC
OS 81048 / CCUG 64013 / CIP 107961 / Muc).
OC Bacteria; Verrucomicrobiota; Verrucomicrobiae; Verrucomicrobiales;
OC Akkermansiaceae; Akkermansia.
OX NCBI_TaxID=349741 {ECO:0000313|EMBL:ACD05243.1, ECO:0000313|Proteomes:UP000001031};
RN [1] {ECO:0000313|Proteomes:UP000001031}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-835 / DSM 22959 / JCM 33894 / BCRC 81048 / CCUG 64013
RC / CIP 107961 / Muc {ECO:0000313|Proteomes:UP000001031};
RX PubMed=21390229; DOI=10.1371/journal.pone.0016876;
RA van Passel M.W., Kant R., Zoetendal E.G., Plugge C.M., Derrien M.,
RA Malfatti S.A., Chain P.S., Woyke T., Palva A., de Vos W.M., Smidt H.;
RT "The genome of Akkermansia muciniphila, a dedicated intestinal mucin
RT degrader, and its use in exploring intestinal metagenomes.";
RL PLoS ONE 6:E16876-E16876(2011).
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DR EMBL; CP001071; ACD05243.1; -; Genomic_DNA.
DR AlphaFoldDB; B2UKX0; -.
DR STRING; 349741.Amuc_1420; -.
DR CAZy; GH97; Glycoside Hydrolase Family 97.
DR PaxDb; 349741-Amuc_1420; -.
DR KEGG; amu:Amuc_1420; -.
DR eggNOG; COG1082; Bacteria.
DR HOGENOM; CLU_011166_1_1_0; -.
DR Proteomes; UP000001031; Chromosome.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:UniProt.
DR GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
DR Gene3D; 2.70.98.10; -; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR014718; GH-type_carb-bd.
DR InterPro; IPR029483; GH97_C.
DR InterPro; IPR019563; GH97_catalytic.
DR InterPro; IPR029486; GH97_N.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR35803; GLUCAN 1,4-ALPHA-GLUCOSIDASE SUSB-RELATED; 1.
DR PANTHER; PTHR35803:SF2; RETAINING ALPHA-GALACTOSIDASE; 1.
DR Pfam; PF14509; GH97_C; 1.
DR Pfam; PF14508; GH97_N; 1.
DR Pfam; PF10566; Glyco_hydro_97; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000001031}.
FT DOMAIN 30..279
FT /note="Glycosyl-hydrolase 97 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF14508"
FT DOMAIN 293..514
FT /note="Glycosyl-hydrolase 97 catalytic"
FT /evidence="ECO:0000259|Pfam:PF10566"
FT DOMAIN 544..639
FT /note="Glycosyl-hydrolase 97 C-terminal oligomerisation"
FT /evidence="ECO:0000259|Pfam:PF14509"
SQ SEQUENCE 649 AA; 71616 MW; 1875F3C25359BCD5 CRC64;
MLVKSLIMLS STAGCLLTGA GQAEETHASL QSPDGRLSWR LHAGSQAAHS LKKGGKTILE
PSGLGVVVNG KNLAGGITGW NVEKVKDNVR DTFETRGKYP TSSVCFNEYV VSGKNSSLRL
RARVFNNGVA FRYEWTEEVK KVPSLNISEE KTSFAFPEKT VLWTQDASSA LGPCEGVWSP
SRITDFKKDP GNPRSCVRTM PITAELPDGG VALIQEAANF NRKWSGIKFS LQDGACHTVY
FQDPGGFSAP SSSEMPWRVI LVNDDLNGLV RNDVIPSLAP EPDRKLFPEG SKASWIRPGR
STWTWWDRGN VLENDQYAFA DMAAEFGWEY HLVDEGWKKW GPSLPESMGK LAKLASYAAG
KNVGIWVWVR WSDVNNPAND WENMRSFFGS LSKTGIRGIK IDFMDSASQE RLAFYDAVAE
NLAKNKLMVN FHGANTPTGE ERSWPHEMSR EGIYGGEQNI WAAIGGQHYC ALPFTRLISG
HADFTGGYFG HGPKLRGSSW TLQMAANIIY TSSMLHWVSN PADMEAAFPK DSPEREVVRN
IPSVWEETIV LPPSAIGECA AFARRSGNQW YIALMNGDGR ERTVSIPLNF LDKNTAYQAT
ILRDLAEKND GWSVETRKVT SGNALSFTMR IKGGGIVRMV PSGTRHPAP
//
