ID   B2ULW6_AKKM8            Unreviewed;       364 AA.
AC   B2ULW6;
DT   01-JUL-2008, integrated into UniProtKB/TrEMBL.
DT   01-JUL-2008, sequence version 1.
DT   27-MAR-2024, entry version 82.
DE   SubName: Full=Twitching motility protein {ECO:0000313|EMBL:ACD04010.1};
GN   OrderedLocusNames=Amuc_0166 {ECO:0000313|EMBL:ACD04010.1};
OS   Akkermansia muciniphila (strain ATCC BAA-835 / DSM 22959 / JCM 33894 / BCRC
OS   81048 / CCUG 64013 / CIP 107961 / Muc).
OC   Bacteria; Verrucomicrobiota; Verrucomicrobiae; Verrucomicrobiales;
OC   Akkermansiaceae; Akkermansia.
OX   NCBI_TaxID=349741 {ECO:0000313|EMBL:ACD04010.1, ECO:0000313|Proteomes:UP000001031};
RN   [1] {ECO:0000313|Proteomes:UP000001031}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-835 / DSM 22959 / JCM 33894 / BCRC 81048 / CCUG 64013
RC   / CIP 107961 / Muc {ECO:0000313|Proteomes:UP000001031};
RX   PubMed=21390229; DOI=10.1371/journal.pone.0016876;
RA   van Passel M.W., Kant R., Zoetendal E.G., Plugge C.M., Derrien M.,
RA   Malfatti S.A., Chain P.S., Woyke T., Palva A., de Vos W.M., Smidt H.;
RT   "The genome of Akkermansia muciniphila, a dedicated intestinal mucin
RT   degrader, and its use in exploring intestinal metagenomes.";
RL   PLoS ONE 6:E16876-E16876(2011).
CC   -!- SIMILARITY: Belongs to the GSP E family.
CC       {ECO:0000256|ARBA:ARBA00006611}.
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DR   EMBL; CP001071; ACD04010.1; -; Genomic_DNA.
DR   RefSeq; WP_012419225.1; NZ_CP071807.1.
DR   AlphaFoldDB; B2ULW6; -.
DR   STRING; 349741.Amuc_0166; -.
DR   PaxDb; 349741-Amuc_0166; -.
DR   GeneID; 60879591; -.
DR   KEGG; amu:Amuc_0166; -.
DR   eggNOG; COG2805; Bacteria.
DR   HOGENOM; CLU_013446_4_0_0; -.
DR   OrthoDB; 9805147at2; -.
DR   BioCyc; AMUC349741:G1GBX-191-MONOMER; -.
DR   Proteomes; UP000001031; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   CDD; cd01131; PilT; 1.
DR   Gene3D; 3.30.450.90; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR006321; PilT/PilU.
DR   InterPro; IPR001482; T2SS/T4SS_dom.
DR   NCBIfam; TIGR01420; pilT_fam; 1.
DR   PANTHER; PTHR30486:SF6; CONJUGAL TRANSFER PROTEIN RV3659C-RELATED; 1.
DR   PANTHER; PTHR30486; TWITCHING MOTILITY PROTEIN PILT; 1.
DR   Pfam; PF00437; T2SSE; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001031}.
FT   DOMAIN          123..257
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
SQ   SEQUENCE   364 AA;  39926 MW;  9A8AB5398A1908BD CRC64;
     MAVIDQYFKY LVEAGGSDLH LSEGQPPKVR VNGTISAISD ENLEGQAFKN LLAEICDPQA
     FQKYLEEGDL DFAYEMDETS RFRCNYFKQQ HGLGAVFRLI PTKIATLEEL GVPTVVKEFA
     HMRSGLVLVT GPTGSGKSTT LAAIIDYINS NQARHIITVE EPIEFVHPNK KSIVTQREVP
     LQTPSFADGL RASLREDSDI VLVGEMRDLE TISLALTAAE TGLLVFGTLH TNNASKTIDR
     IIDVFPSDQQ SQVRTMLAGS LRGVVAQLLM KRSDKPGRVA VNEILFATPA VAAIIREGAT
     QKIPDVIVGG KAMGMQFMDD AIWQKLQQGI VSPEEAYMKC IEKKRFRNFL PPESARLADS
     GGGN
//