ID B2VVG8_PYRTR Unreviewed; 820 AA.
AC B2VVG8;
DT 01-JUL-2008, integrated into UniProtKB/TrEMBL.
DT 01-JUL-2008, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE RecName: Full=Vacuolar protein 14 C-terminal Fig4-binding domain-containing protein {ECO:0000259|Pfam:PF11916};
GN ORFNames=PTRG_02283 {ECO:0000313|EMBL:EDU41721.1};
OS Pyrenophora tritici-repentis (strain Pt-1C-BFP) (Wheat tan spot fungus)
OS (Drechslera tritici-repentis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae;
OC Pyrenophora.
OX NCBI_TaxID=426418 {ECO:0000313|EMBL:EDU41721.1, ECO:0000313|Proteomes:UP000001471};
RN [1] {ECO:0000313|Proteomes:UP000001471}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Pt-1C-BFP {ECO:0000313|Proteomes:UP000001471};
RX PubMed=23316438; DOI=10.1534/g3.112.004044;
RA Manning V.A., Pandelova I., Dhillon B., Wilhelm L.J., Goodwin S.B.,
RA Berlin A.M., Figueroa M., Freitag M., Hane J.K., Henrissat B., Holman W.H.,
RA Kodira C.D., Martin J., Oliver R.P., Robbertse B., Schackwitz W.,
RA Schwartz D.C., Spatafora J.W., Turgeon B.G., Yandava C., Young S., Zhou S.,
RA Zeng Q., Grigoriev I.V., Ma L.-J., Ciuffetti L.M.;
RT "Comparative genomics of a plant-pathogenic fungus, Pyrenophora tritici-
RT repentis, reveals transduplication and the impact of repeat elements on
RT pathogenicity and population divergence.";
RL G3 (Bethesda) 3:41-63(2013).
CC -!- SIMILARITY: Belongs to the VAC14 family.
CC {ECO:0000256|ARBA:ARBA00010225}.
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DR EMBL; DS231615; EDU41721.1; -; Genomic_DNA.
DR RefSeq; XP_001932616.1; XM_001932581.1.
DR AlphaFoldDB; B2VVG8; -.
DR STRING; 426418.B2VVG8; -.
DR EnsemblFungi; EDU41721; EDU41721; PTRG_02283.
DR GeneID; 6338407; -.
DR eggNOG; KOG0212; Eukaryota.
DR HOGENOM; CLU_007740_0_0_1; -.
DR InParanoid; B2VVG8; -.
DR OMA; CYQHVSE; -.
DR OrthoDB; 5481081at2759; -.
DR Proteomes; UP000001471; Unassembled WGS sequence.
DR GO; GO:0000329; C:fungal-type vacuole membrane; IEA:EnsemblFungi.
DR GO; GO:0070772; C:PAS complex; IEA:EnsemblFungi.
DR GO; GO:0042802; F:identical protein binding; IEA:EnsemblFungi.
DR GO; GO:0030674; F:protein-macromolecule adaptor activity; IEA:EnsemblFungi.
DR GO; GO:0006661; P:phosphatidylinositol biosynthetic process; IEA:EnsemblFungi.
DR GO; GO:0042327; P:positive regulation of phosphorylation; IEA:EnsemblFungi.
DR GO; GO:1903778; P:protein localization to vacuolar membrane; IEA:EnsemblFungi.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR026825; Vac14.
DR InterPro; IPR021841; VAC14_Fig4p-bd.
DR PANTHER; PTHR16023:SF0; PROTEIN VAC14 HOMOLOG; 1.
DR PANTHER; PTHR16023; TAX1 BINDING PROTEIN-RELATED; 1.
DR Pfam; PF12755; Vac14_Fab1_bd; 1.
DR Pfam; PF11916; Vac14_Fig4_bd; 2.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50077; HEAT_REPEAT; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000001471};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 87..122
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT DOMAIN 626..694
FT /note="Vacuolar protein 14 C-terminal Fig4-binding"
FT /evidence="ECO:0000259|Pfam:PF11916"
FT DOMAIN 695..771
FT /note="Vacuolar protein 14 C-terminal Fig4-binding"
FT /evidence="ECO:0000259|Pfam:PF11916"
FT REGION 274..339
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 455..481
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 495..527
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 785..820
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 274..293
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 461..481
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 820 AA; 91151 MW; 510F913C8CE7DB4B CRC64;
MDANITKALN DKLYDKRKSG ALELEGLIRD ALAVQDHDRI AKIVHQLCHE YAYAVHQPHA
RNGGLIGLAA ASIALGPQEV ARYLEEIVPP VLACFSDQDA RVRYYACESM YNIAKVAKGE
ILVYFNQVFD ALCKMAADSE LSVKNGAELL DRLIKDIVSE SAASYVSVLH TSPDQQDPND
EPHPYAFSLE RFLPLLEERI NVLNPYTRSF LVAWITLLDS IPDLELIAHL PRFLGGLFKF
LSDSNTDVYT MTQAALDRFL SEIKKIARIK KGIADSKRSN SKDERRHSAD SLHSASEATD
TTPMEPLDSM DDRNDMSGES ASVSEDSDKS VTGDENWIPG QDVHVDHPKI LEILVDFLVP
PPGKSSAYGA MATQLTLTDT EEEQTEIVLT ALRWIDNLFD ICPEDIMPFV PSLLSHVLPR
MSHEVDTVRK AAVKVNAALM DYILSLSDDN RLRDGAGSGQ IQLPPSLSEL GKELTGTQRR
DSNLSGRLLK AVIRDQANKA ESPDGKATRS STPAEAEERG PSPRPIPELD YQAAVSALTL
QFLNEHEATR VAAIAWLIML HRMAPGRILT VDDGTFPALL KTLSDPSDAV VTRDLLLLSQ
ISLHSDDTYF TSFMVNLLKL FCTDRRLLET RGNLIIRQLC LTLSAERIYR TMADCLAKDE
DVEFASIMVQ NLNNNLITAP ELADLRRRLR NLDNRAYHLL QVFADLEMTV NMLIQIDKLV
QLLESPVFTY LRMQLLEPER YPYLYKCMYG LLMLLPQSSA FAALKNRLNS VSAIGYLHIA
PQRSSSTYVH PSSSSPTLNH LRQKSSEIGS NSSSGSGLAG
//
