ID B2WDE0_PYRTR Unreviewed; 543 AA.
AC B2WDE0;
DT 01-JUL-2008, integrated into UniProtKB/TrEMBL.
DT 01-JUL-2008, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE RecName: Full=methylmalonate-semialdehyde dehydrogenase (CoA acylating) {ECO:0000256|ARBA:ARBA00013048};
DE EC=1.2.1.27 {ECO:0000256|ARBA:ARBA00013048};
GN ORFNames=PTRG_07999 {ECO:0000313|EMBL:EDU50918.1};
OS Pyrenophora tritici-repentis (strain Pt-1C-BFP) (Wheat tan spot fungus)
OS (Drechslera tritici-repentis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae;
OC Pyrenophora.
OX NCBI_TaxID=426418 {ECO:0000313|EMBL:EDU50918.1, ECO:0000313|Proteomes:UP000001471};
RN [1] {ECO:0000313|Proteomes:UP000001471}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Pt-1C-BFP {ECO:0000313|Proteomes:UP000001471};
RX PubMed=23316438; DOI=10.1534/g3.112.004044;
RA Manning V.A., Pandelova I., Dhillon B., Wilhelm L.J., Goodwin S.B.,
RA Berlin A.M., Figueroa M., Freitag M., Hane J.K., Henrissat B., Holman W.H.,
RA Kodira C.D., Martin J., Oliver R.P., Robbertse B., Schackwitz W.,
RA Schwartz D.C., Spatafora J.W., Turgeon B.G., Yandava C., Young S., Zhou S.,
RA Zeng Q., Grigoriev I.V., Ma L.-J., Ciuffetti L.M.;
RT "Comparative genomics of a plant-pathogenic fungus, Pyrenophora tritici-
RT repentis, reveals transduplication and the impact of repeat elements on
RT pathogenicity and population divergence.";
RL G3 (Bethesda) 3:41-63(2013).
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DR EMBL; DS231622; EDU50918.1; -; Genomic_DNA.
DR RefSeq; XP_001938331.1; XM_001938296.1.
DR AlphaFoldDB; B2WDE0; -.
DR STRING; 426418.B2WDE0; -.
DR EnsemblFungi; EDU50918; EDU50918; PTRG_07999.
DR GeneID; 6346276; -.
DR eggNOG; KOG2449; Eukaryota.
DR HOGENOM; CLU_005391_1_10_1; -.
DR InParanoid; B2WDE0; -.
DR OMA; GGAKNHI; -.
DR OrthoDB; 275238at2759; -.
DR Proteomes; UP000001471; Unassembled WGS sequence.
DR GO; GO:0004491; F:methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity; IEA:UniProtKB-EC.
DR CDD; cd07085; ALDH_F6_MMSDH; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR010061; MeMal-semiAld_DH.
DR NCBIfam; TIGR01722; MMSDH; 1.
DR PANTHER; PTHR43866; MALONATE-SEMIALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR43866:SF3; METHYLMALONATE-SEMIALDEHYDE DEHYDROGENASE [ACYLATING], MITOCHONDRIAL; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001471}.
FT DOMAIN 55..521
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
SQ SEQUENCE 543 AA; 58444 MW; 9831EF79682C7636 CRC64;
MSSPVSQSKV AARRLHATAQ HLKPASSAVA ESYPMNHEPI KSPTDTPNFV DNKFVASKAT
QWIDLHDPAT NNLVTRVPQS TDEELKAAVD SAEKAFKPWK ETSLLHRQQI LFKYTHLIRE
NWDRLAASIT LEQGKTFADA RGDVLRGLQV AETACGITTQ MTGEVLEVAK DMETRSYREP
LGVVAAICPF NFPAMIPLWT IPIAAVTGNT CVIKPSERDP GACMILAELA EKAGFPPGVI
NIVHGAAKTV DFIIDEPRIK AISFVGSNQA GEYIYARASA KGKRVQANLG AKNHAAVLPD
CNKNHALNAI AGAAFGAAGQ RCMALSTLVM IGETKDWVPE IAERAKELSM NGGFEEGADL
GPVISPQSKK RIEDLIASAE EEGATILLDG RGQKPSSEKY ANGNWVGPTI IANVKPHMKC
YKEEIFGPVL VCLNVETIDE AIDMINANEY GNGTAIFTRS GATAGRFQRE IEAGQVGINV
PIPVPLPMFS FTGNKKSVAG GGASTFYGKP GLQFYTQQKT VTSLWRSEDA VATKASVNMP
THS
//
