GenomeNet

Database: UniProt
Entry: B2WIZ6_PYRTR
LinkDB: B2WIZ6_PYRTR
Original site: B2WIZ6_PYRTR 
ID   B2WIZ6_PYRTR            Unreviewed;      1115 AA.
AC   B2WIZ6;
DT   01-JUL-2008, integrated into UniProtKB/TrEMBL.
DT   01-JUL-2008, sequence version 1.
DT   05-JUN-2019, entry version 72.
DE   RecName: Full=DNA polymerase {ECO:0000256|RuleBase:RU000442};
DE            EC=2.7.7.7 {ECO:0000256|RuleBase:RU000442};
GN   ORFNames=PTRG_09955 {ECO:0000313|EMBL:EDU43006.1};
OS   Pyrenophora tritici-repentis (strain Pt-1C-BFP) (Wheat tan spot
OS   fungus) (Drechslera tritici-repentis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
OC   Dothideomycetes; Pleosporomycetidae; Pleosporales; Pleosporineae;
OC   Pleosporaceae; Pyrenophora.
OX   NCBI_TaxID=426418 {ECO:0000313|EMBL:EDU43006.1, ECO:0000313|Proteomes:UP000001471};
RN   [1] {ECO:0000313|Proteomes:UP000001471}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Pt-1C-BFP {ECO:0000313|Proteomes:UP000001471};
RX   PubMed=23316438; DOI=10.1534/g3.112.004044;
RA   Manning V.A., Pandelova I., Dhillon B., Wilhelm L.J., Goodwin S.B.,
RA   Berlin A.M., Figueroa M., Freitag M., Hane J.K., Henrissat B.,
RA   Holman W.H., Kodira C.D., Martin J., Oliver R.P., Robbertse B.,
RA   Schackwitz W., Schwartz D.C., Spatafora J.W., Turgeon B.G.,
RA   Yandava C., Young S., Zhou S., Zeng Q., Grigoriev I.V., Ma L.-J.,
RA   Ciuffetti L.M.;
RT   "Comparative genomics of a plant-pathogenic fungus, Pyrenophora
RT   tritici-repentis, reveals transduplication and the impact of repeat
RT   elements on pathogenicity and population divergence.";
RL   G3 (Bethesda) 3:41-63(2013).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC         diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-
CC         COMP:11130, Rhea:RHEA-COMP:11131, ChEBI:CHEBI:33019,
CC         ChEBI:CHEBI:61560, ChEBI:CHEBI:83828; EC=2.7.7.7;
CC         Evidence={ECO:0000256|RuleBase:RU000442};
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|RuleBase:RU000442};
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU000442}.
CC   -!- SIMILARITY: Belongs to the DNA polymerase type-B family.
CC       {ECO:0000256|RuleBase:RU000442}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; DS231626; EDU43006.1; -; Genomic_DNA.
DR   RefSeq; XP_001940287.1; XM_001940252.1.
DR   STRING; 45151.EDU43006; -.
DR   EnsemblFungi; EDU43006; EDU43006; PTRG_09955.
DR   GeneID; 6348253; -.
DR   eggNOG; KOG0969; Eukaryota.
DR   eggNOG; COG0417; LUCA.
DR   InParanoid; B2WIZ6; -.
DR   OMA; CLVNYTE; -.
DR   OrthoDB; 20210at2759; -.
DR   Proteomes; UP000001471; Unassembled WGS sequence.
DR   GO; GO:0043625; C:delta DNA polymerase complex; IEA:EnsemblFungi.
DR   GO; GO:0000784; C:nuclear chromosome, telomeric region; IEA:EnsemblFungi.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:1904161; P:DNA synthesis involved in UV-damage excision repair; IEA:EnsemblFungi.
DR   GO; GO:1903459; P:mitotic DNA replication lagging strand elongation; IEA:EnsemblFungi.
DR   Gene3D; 1.10.132.60; -; 1.
DR   Gene3D; 3.30.420.10; -; 1.
DR   Gene3D; 3.90.1600.10; -; 1.
DR   InterPro; IPR006172; DNA-dir_DNA_pol_B.
DR   InterPro; IPR017964; DNA-dir_DNA_pol_B_CS.
DR   InterPro; IPR006133; DNA-dir_DNA_pol_B_exonuc.
DR   InterPro; IPR006134; DNA-dir_DNA_pol_B_multi_dom.
DR   InterPro; IPR042087; DNA_pol_B_C.
DR   InterPro; IPR023211; DNA_pol_palm_dom_sf.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR025687; Znf-C4pol.
DR   Pfam; PF00136; DNA_pol_B; 1.
DR   Pfam; PF03104; DNA_pol_B_exo1; 1.
DR   Pfam; PF14260; zf-C4pol; 1.
DR   PRINTS; PR00106; DNAPOLB.
DR   SMART; SM00486; POLBc; 1.
DR   SUPFAM; SSF53098; SSF53098; 1.
DR   PROSITE; PS00116; DNA_POLYMERASE_B; 1.
PE   3: Inferred from homology;
KW   4Fe-4S {ECO:0000256|RuleBase:RU000442};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001471};
KW   DNA replication {ECO:0000256|RuleBase:RU000442};
KW   DNA-binding {ECO:0000256|RuleBase:RU000442};
KW   DNA-directed DNA polymerase {ECO:0000256|RuleBase:RU000442};
KW   Iron {ECO:0000256|RuleBase:RU000442};
KW   Iron-sulfur {ECO:0000256|RuleBase:RU000442};
KW   Metal-binding {ECO:0000256|RuleBase:RU000442};
KW   Nucleotidyltransferase {ECO:0000256|RuleBase:RU000442};
KW   Nucleus {ECO:0000256|RuleBase:RU000442};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001471};
KW   Transferase {ECO:0000256|RuleBase:RU000442};
KW   Zinc {ECO:0000256|RuleBase:RU000442};
KW   Zinc-finger {ECO:0000256|RuleBase:RU000442}.
FT   DOMAIN      130    476       DNA_pol_B_exo1. {ECO:0000259|Pfam:
FT                                PF03104}.
FT   DOMAIN      540    979       DNA_pol_B. {ECO:0000259|Pfam:PF00136}.
FT   DOMAIN     1017   1091       zf-C4pol. {ECO:0000259|Pfam:PF14260}.
FT   REGION        1     92       Disordered. {ECO:0000256|MobiDB-lite:
FT                                B2WIZ6}.
FT   COMPBIAS      8     33       Polar. {ECO:0000256|MobiDB-lite:B2WIZ6}.
FT   COMPBIAS     43     64       Polar. {ECO:0000256|MobiDB-lite:B2WIZ6}.
FT   COMPBIAS     67     92       Polyampholyte. {ECO:0000256|MobiDB-lite:
FT                                B2WIZ6}.
SQ   SEQUENCE   1115 AA;  126811 MW;  1601C0B3799CB3C0 CRC64;
     MAGTDSKAPS KRTLSETSGK RNNVQLSPRS SKKLKLENTN ERSRAPIKTA NGSFNSSQPA
     PSQFEETLER MAEDVESVKK GNKEKDQEWH RPAIPEDFSE MTHNLTFQQI DAEEGVLNGG
     RATVKLFGVT ENGHSVLLHV TGFQHYFYVA APIDFHKEDC EGYKLFLEGE CQKNFNQHSA
     VIASVQMCMR ENILRFQGNQ KSPYLKITVC DPKMINRVRM MVQKGNANYK RLWPAREDGI
     LTFDNIAYVL RFMIDTSVTG MCWVEAPASK YRMINPRERH SNCQFEAQVH YKDLIAHSSE
     GEWAKLAPLR VLSFDIECAG RKGIFPEANV DPVIQIANVV TRYGEQKPFV RNVFCLDTVS
     PIVSTEIFSY QSEGEMLMKW RDFVEQVDPD VIIGYNINNF DFPYLLDRAK HLKLQKFPYW
     TRLKTVQSKV ESSHFSSKQL GNRDTKTTNT NGRLQLDLLQ LIQRDHHLRS YTLNSVCAHF
     LKEQKEDVHH SMITELFNGD CNSRRRLAVY CLKDAYLPQR LLDKLMCLVN YTEMARVTGV
     PFNYILSRGQ QIRFISQLFR KALDHQLIIP DLPNQGDSND QYEGATVIEP KRGYYRDPVA
     TLDFASLYPS IMQAHNLCYT TWLDKQTVEK LKMKKDEDYI VTPHGDMFCT AKTRKGLLTE
     ILEEVLSARK KAKRELATET DPFKKAVLNG RQLALKVTAN SVYGLTGATN GKLPCLAIAS
     STTSFGRQMI ERTKAEVEAK YNIANGYTHD AEVIYGDTDS VMVKFGTSNL EEAMKLGEEA
     ATYVTSKFLK PIKLEFEKVY FPYLLINKKR YAGLYWTNPH KWDKMDTKGI ETVRRDNCRL
     VQTVIETSLR MLLIDQDPEG AQAFVKETIA DLLQNKVDMS NLVITKALTK QEDKDGKGGY
     ANKQAHVELA ERMKKRDAGS APALGDRVAY VMIRAATGAK NFEKSEDPLY VLENNLPIDT
     RYYLDNQLAK PLGRIFEPIL GEKKAASLLT GDHTRSITVA APTMGGLMKF AKKTSTCMGC
     KKPLVAAHEK DGAVCENCRP RIGELYTKTL SKVSELEVRF SRLWTQCQRC QGSVHCEVIC
     ASKDCPIFYM RMKARKDVQD AGKELVRFDK DAALW
//
DBGET integrated database retrieval system