ID B2WJH7_PYRTR Unreviewed; 599 AA.
AC B2WJH7;
DT 01-JUL-2008, integrated into UniProtKB/TrEMBL.
DT 01-JUL-2008, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Trichothecene efflux pump {ECO:0000313|EMBL:EDU43374.1};
GN ORFNames=PTRG_10323 {ECO:0000313|EMBL:EDU43374.1};
OS Pyrenophora tritici-repentis (strain Pt-1C-BFP) (Wheat tan spot fungus)
OS (Drechslera tritici-repentis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae;
OC Pyrenophora.
OX NCBI_TaxID=426418 {ECO:0000313|EMBL:EDU43374.1, ECO:0000313|Proteomes:UP000001471};
RN [1] {ECO:0000313|Proteomes:UP000001471}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Pt-1C-BFP {ECO:0000313|Proteomes:UP000001471};
RX PubMed=23316438; DOI=10.1534/g3.112.004044;
RA Manning V.A., Pandelova I., Dhillon B., Wilhelm L.J., Goodwin S.B.,
RA Berlin A.M., Figueroa M., Freitag M., Hane J.K., Henrissat B., Holman W.H.,
RA Kodira C.D., Martin J., Oliver R.P., Robbertse B., Schackwitz W.,
RA Schwartz D.C., Spatafora J.W., Turgeon B.G., Yandava C., Young S., Zhou S.,
RA Zeng Q., Grigoriev I.V., Ma L.-J., Ciuffetti L.M.;
RT "Comparative genomics of a plant-pathogenic fungus, Pyrenophora tritici-
RT repentis, reveals transduplication and the impact of repeat elements on
RT pathogenicity and population divergence.";
RL G3 (Bethesda) 3:41-63(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; DS231627; EDU43374.1; -; Genomic_DNA.
DR RefSeq; XP_001940655.1; XM_001940620.1.
DR AlphaFoldDB; B2WJH7; -.
DR EnsemblFungi; EDU43374; EDU43374; PTRG_10323.
DR GeneID; 6348624; -.
DR eggNOG; KOG0254; Eukaryota.
DR HOGENOM; CLU_000960_25_2_1; -.
DR InParanoid; B2WJH7; -.
DR OMA; PRMKIQM; -.
DR OrthoDB; 2103161at2759; -.
DR Proteomes; UP000001471; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd06179; MFS_TRI12_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR010573; MFS_Str1/Tri12-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR005829; Sugar_transporter_CS.
DR PANTHER; PTHR23501; MAJOR FACILITATOR SUPERFAMILY; 1.
DR PANTHER; PTHR23501:SF109; MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR Pfam; PF06609; TRI12; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS00216; SUGAR_TRANSPORT_1; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001471};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 52..73
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 93..110
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 122..141
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 180..199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 211..233
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 260..279
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 291..312
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 332..354
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 366..384
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 396..414
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 426..448
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 454..476
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 546..564
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 57..569
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 599 AA; 64574 MW; 53F8EDB19D586367 CRC64;
MADQKQYTEE TIRNSSITQE HTSLSHGLHH DHVAEEALGG HRADLGKSYF TSFNFIGTVI
ATCLAQISGY LGWVLPANTL SLINASIGPS PNIIWVSISW TAGFAIGFTL VGRLSDIFGR
RWFFICSSLF GLIGNIIGSS AQSINMLIAT NSINGLAAAG QLSFHIILGE LVPNALRGPV
NAFVLFTSVP FAVFGPPVAR SLYQTTALQW RWCYILGCIV NVLAMVLYFF FYFPPTYLTA
KEMLHVGGKS KLRQLKTLDW MGIFLFSTGL VVFLIGMNWG GSAYPWKSGH VLGALFSGFA
TMVAFCFWEA YAPGLEYPLI PLRLFRNVQY DANVACASLA AIVYYANTVI WPTMVSSLFT
TDITRIGWLS CAVGGGLLLG QILGGAGVRY LPRMKVQMTV AAVFTTAFVA AVSASNHNTE
QRTTAFLLIG TIAAGYIENL TLSSTAYLWD PADIGLVTGV MGAIRTGLSA IATSMYSSIL
TTEASKYIPQ KVIPAALAAG LPEASIPELL SSISLGDFTA VPGITPNIVA ATGDAVKAAY
ALSFRTIYLC TLPFGVLLIA AALLSPNVEP YLTDEVARKM HDRTEEKKDQ VVKKEFVDA
//
