GenomeNet

Database: UniProt
Entry: B3CKG6_SIV
LinkDB: B3CKG6_SIV
Original site: B3CKG6_SIV 
ID   B3CKG6_SIV              Unreviewed;       230 AA.
AC   B3CKG6;
DT   22-JUL-2008, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2008, sequence version 1.
DT   12-AUG-2020, entry version 40.
DE   RecName: Full=Protein Nef {ECO:0000256|RuleBase:RU000344};
GN   Name=nef {ECO:0000313|EMBL:CAP72511.1};
OS   SIV-wrc Pbt-05GM-X02.
OC   Viruses; Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus.
OX   NCBI_TaxID=498715 {ECO:0000313|EMBL:CAP72511.1, ECO:0000313|Proteomes:UP000257744};
RN   [1] {ECO:0000313|EMBL:CAP72511.1, ECO:0000313|Proteomes:UP000257744}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=wrcPbt-05GM-X02 {ECO:0000313|Proteomes:UP000257744};
RX   PubMed=18442839; DOI=10.1016/j.virol.2008.01.049;
RA   Locatelli S., Lafay B., Liegeois F., Ting N., Delaporte E., Peeters M.;
RT   "Full molecular characterization of a simian immunodeficiency virus,
RT   SIVwrcpbt from Temminck's red colobus (Piliocolobus badius temminckii) from
RT   Abuko Nature Reserve, The Gambia.";
RL   Virology 376:90-100(2008).
CC   -!- SIMILARITY: Belongs to the lentivirus primate group Nef protein family.
CC       {ECO:0000256|ARBA:ARBA00006933, ECO:0000256|RuleBase:RU000344}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AM937062; CAP72511.1; -; Genomic_DNA.
DR   Proteomes; UP000257744; Genome.
DR   GO; GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   GO; GO:0030683; P:mitigation of host immune response by virus; IEA:UniProtKB-KW.
DR   GO; GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.62.10; -; 1.
DR   InterPro; IPR027481; HIV-1_Nef_core_sf.
DR   InterPro; IPR001558; HIV_Nef.
DR   Pfam; PF00469; F-protein; 1.
DR   SUPFAM; SSF55671; SSF55671; 1.
PE   3: Inferred from homology;
KW   Host-virus interaction {ECO:0000256|ARBA:ARBA00022581};
KW   Lipoprotein {ECO:0000256|RuleBase:RU000344};
KW   Myristate {ECO:0000256|ARBA:ARBA00022707, ECO:0000256|RuleBase:RU000344};
KW   Reference proteome {ECO:0000313|Proteomes:UP000257744};
KW   Viral immunoevasion {ECO:0000256|ARBA:ARBA00023280,
KW   ECO:0000256|RuleBase:RU000344};
KW   Virulence {ECO:0000256|ARBA:ARBA00023026, ECO:0000256|RuleBase:RU000344}.
SQ   SEQUENCE   230 AA;  26594 MW;  85CD460C04759AB9 CRC64;
     MGGVFSKDSV EQRMLRYRRR LLRVGRKERR RRYTRLAAER QAEAAASGEL LPDSAQTLIR
     AEEDSSKEDS SDDDAIGFPV RPQVPLRQAT FKILVDLSHL FKEKGGLEDI FWSPRREEIV
     NLYAYHEWGI VEGWQAYTDG PGVRYPKTFG WCWKLVPVHF SEESPNSDQG FEKNLLLHPA
     VAESEDPWKE YLVWKFDPRL ACDFVAGRLA DGQIATGIET LYEMKKRNNK
//
DBGET integrated database retrieval system