ID B3CKG9_SIV Unreviewed; 208 AA.
AC B3CKG9;
DT 22-JUL-2008, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2008, sequence version 1.
DT 10-FEB-2021, entry version 42.
DE RecName: Full=Virion infectivity factor {ECO:0000256|RuleBase:RU003341};
GN Name=vif {ECO:0000313|EMBL:CAP72505.1};
OS SIV-wrc Pbt-05GM-X02.
OC Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus.
OX NCBI_TaxID=498715 {ECO:0000313|EMBL:CAP72505.1, ECO:0000313|Proteomes:UP000257744};
RN [1] {ECO:0000313|EMBL:CAP72505.1, ECO:0000313|Proteomes:UP000257744}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=wrcPbt-05GM-X02 {ECO:0000313|Proteomes:UP000257744};
RX PubMed=18442839; DOI=10.1016/j.virol.2008.01.049;
RA Locatelli S., Lafay B., Liegeois F., Ting N., Delaporte E., Peeters M.;
RT "Full molecular characterization of a simian immunodeficiency virus,
RT SIVwrcpbt from Temminck's red colobus (Piliocolobus badius temminckii) from
RT Abuko Nature Reserve, The Gambia.";
RL Virology 376:90-100(2008).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004413};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004413};
CC Cytoplasmic side {ECO:0000256|ARBA:ARBA00004413}. Host cell membrane
CC {ECO:0000256|ARBA:ARBA00004501, ECO:0000256|RuleBase:RU003341};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004501,
CC ECO:0000256|RuleBase:RU003341}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004501, ECO:0000256|RuleBase:RU003341}. Host
CC cytoplasm {ECO:0000256|RuleBase:RU003341}. Virion
CC {ECO:0000256|RuleBase:RU003341}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}. Note=In the cytoplasm, seems to
CC colocalize with intermediate filament vimentin. A fraction is
CC associated with the cytoplasmic side of cellular membranes, presumably
CC via the interaction with Pr55Gag precursor.
CC {ECO:0000256|RuleBase:RU003341}.
CC -!- SIMILARITY: Belongs to the primate lentivirus group Vif protein family.
CC {ECO:0000256|ARBA:ARBA00006372, ECO:0000256|RuleBase:RU003341}.
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DR EMBL; AM937062; CAP72505.1; -; Genomic_DNA.
DR Proteomes; UP000257744; Genome.
DR GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0019012; C:virion; IEA:UniProtKB-SubCell.
DR GO; GO:0019058; P:viral life cycle; IEA:InterPro.
DR InterPro; IPR000475; Vif.
DR Pfam; PF00559; Vif; 1.
DR PRINTS; PR00349; VIRIONINFFCT.
PE 3: Inferred from homology;
KW Host cytoplasm {ECO:0000256|ARBA:ARBA00023200};
KW Reference proteome {ECO:0000313|Proteomes:UP000257744};
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
SQ SEQUENCE 208 AA; 24369 MW; C0C35A07FB192E87 CRC64;
MEKEWIAVPL IKISKGRFRR WSYWIAELIQ EKQARFLFGS WHVHAECFTR HIVRIPLQGH
WEMQIRCYWN LAPEIGWIDT LGFNIRMVWE NKWETFITVK LADVLIHSQH FECWTQSAVK
NTIRQGYLHP IDSCKYHQGH LGVLTLQALC LQALQHEQLR KRKAPNRRTP GNTRGSSRYA
RAVCHGKTAF PPGSPCKSIS LLLATEKL
//