ID B3DM26_XENTR Unreviewed; 282 AA.
AC B3DM26;
DT 22-JUL-2008, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2008, sequence version 1.
DT 27-MAR-2024, entry version 100.
DE SubName: Full=Homeobox protein vex1 {ECO:0000313|RefSeq:NP_001123388.1};
DE SubName: Full=VENT homeobox 3, gene 2 {ECO:0000313|Ensembl:ENSXETP00000058808};
DE SubName: Full=Ventx3.2 protein {ECO:0000313|EMBL:AAI67675.1};
GN Name=ventx3.2 {ECO:0000313|EMBL:AAI67675.1,
GN ECO:0000313|Ensembl:ENSXETP00000058808,
GN ECO:0000313|RefSeq:NP_001123388.1,
GN ECO:0000313|Xenbase:XB-GENE-483077};
GN Synonyms=ventx3 {ECO:0000313|Xenbase:XB-GENE-483077}, vex1
GN {ECO:0000313|RefSeq:NP_001123388.1}, Xvex-1
GN {ECO:0000313|RefSeq:NP_001123388.1};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|EMBL:AAI67675.1};
RN [1] {ECO:0000313|RefSeq:NP_001123388.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=12454917; DOI=10.1002/dvdy.10174;
RA Klein S.L., Strausberg R.L., Wagner L., Pontius J., Clifton S.W.,
RA Richardson P.;
RT "Genetic and genomic tools for Xenopus research: The NIH Xenopus
RT initiative.";
RL Dev. Dyn. 225:384-391(2002).
RN [2] {ECO:0000313|EMBL:AAI67675.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Whole embryo {ECO:0000313|EMBL:AAI67675.1};
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSXETP00000058808}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000058808};
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [4] {ECO:0000313|Ensembl:ENSXETP00000058808}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAY-2020) to UniProtKB.
RN [5] {ECO:0000313|RefSeq:NP_001123388.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
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DR EMBL; BC167675; AAI67675.1; -; mRNA.
DR RefSeq; NP_001123388.1; NM_001129916.1.
DR Ensembl; ENSXETT00000065382; ENSXETP00000058808; ENSXETG00000033622.
DR GeneID; 100170150; -.
DR KEGG; xtr:100170150; -.
DR AGR; Xenbase:XB-GENE-483077; -.
DR CTD; 100170150; -.
DR Xenbase; XB-GENE-483077; ventx3.2.
DR HOGENOM; CLU_986824_0_0_1; -.
DR OMA; INEPMSH; -.
DR OrthoDB; 1407739at2759; -.
DR TreeFam; TF351607; -.
DR Proteomes; UP000008143; Chromosome 7.
DR Bgee; ENSXETG00000033622; Expressed in gastrula and 4 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR PANTHER; PTHR24333; HOMEO BOX HB9 LIKE A-RELATED; 1.
DR PANTHER; PTHR24333:SF12; HOMEOBOX PROTEIN CEH-62; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 2: Evidence at transcript level;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000008143}.
FT DOMAIN 127..187
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 129..188
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
SQ SEQUENCE 282 AA; 32084 MW; D17431345654BEA7 CRC64;
MEKRPYSVAW LSESSQRKPL CTNVDLLGYK SGNPDLPPNR EYNVSLPSRV ILPTPDYREK
ENYCGRNVHN GERSPPVRDQ LHFHPAPQEL TTSRRTSIEV SAESSTDQRV IGMTDTNKKT
KSVCDEDAAS RARTKFTAEQ LEELEKSFKE NRYIGSSEKR RLSKVLKLSE NQIKTWFQNR
RMKFKRQTQD ARVEAFFSGL YLPYYGYPDL PTPGYSVQSE FPVLAPQTMA ASSIPFGPLH
STVMSPGLHP AIPSANLGSY PCSSMLVRPI LNEPTRQRYS PY
//
