ID B3M1D3_DROAN Unreviewed; 1185 AA.
AC B3M1D3;
DT 02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 02-SEP-2008, sequence version 1.
DT 24-JAN-2024, entry version 89.
DE RecName: Full=F-box domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=Dana\GF17149 {ECO:0000313|EMBL:EDV42160.1};
GN Synonyms=dana_GLEANR_18415 {ECO:0000313|EMBL:EDV42160.1};
GN ORFNames=GF17149 {ECO:0000313|EMBL:EDV42160.1};
OS Drosophila ananassae (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7217 {ECO:0000313|EMBL:EDV42160.1, ECO:0000313|Proteomes:UP000007801};
RN [1] {ECO:0000313|EMBL:EDV42160.1, ECO:0000313|Proteomes:UP000007801}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 14024-0371.13 {ECO:0000313|Proteomes:UP000007801};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
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DR EMBL; CH902617; EDV42160.1; -; Genomic_DNA.
DR RefSeq; XP_001953599.1; XM_001953563.2.
DR AlphaFoldDB; B3M1D3; -.
DR SMR; B3M1D3; -.
DR STRING; 7217.B3M1D3; -.
DR EnsemblMetazoa; FBtr0121849; FBpp0120341; FBgn0094168.
DR GeneID; 6499937; -.
DR KEGG; dan:6499937; -.
DR eggNOG; KOG1777; Eukaryota.
DR HOGENOM; CLU_005078_0_0_1; -.
DR InParanoid; B3M1D3; -.
DR OMA; KESFHQL; -.
DR OrthoDB; 5491826at2759; -.
DR PhylomeDB; B3M1D3; -.
DR Proteomes; UP000007801; Unassembled WGS sequence.
DR GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:EnsemblMetazoa.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:1900368; P:regulation of post-transcriptional gene silencing by regulatory ncRNA; IEA:EnsemblMetazoa.
DR GO; GO:0070922; P:RISC complex assembly; IEA:EnsemblMetazoa.
DR CDD; cd22091; F-box_FBXO11; 1.
DR CDD; cd19676; UBR-box_UBR6_FBXO11; 1.
DR Gene3D; 1.20.1280.50; -; 1.
DR Gene3D; 2.160.20.10; Single-stranded right-handed beta-helix, Pectin lyase-like; 3.
DR InterPro; IPR039448; Beta_helix.
DR InterPro; IPR006633; Carb-bd_sugar_hydrolysis-dom.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR047505; F-box_FBXO11.
DR InterPro; IPR047504; FBXO11_UBR-box.
DR InterPro; IPR007742; NosD_dom.
DR InterPro; IPR022441; Para_beta_helix_rpt-2.
DR InterPro; IPR006626; PbH1.
DR InterPro; IPR012334; Pectin_lyas_fold.
DR InterPro; IPR011050; Pectin_lyase_fold/virulence.
DR InterPro; IPR003126; Znf_UBR.
DR NCBIfam; TIGR03804; para_beta_helix; 2.
DR PANTHER; PTHR22990; F-BOX ONLY PROTEIN; 1.
DR PANTHER; PTHR22990:SF20; F-BOX ONLY PROTEIN 11; 1.
DR Pfam; PF13229; Beta_helix; 2.
DR Pfam; PF12937; F-box-like; 1.
DR Pfam; PF05048; NosD; 1.
DR Pfam; PF02207; zf-UBR; 1.
DR SMART; SM00722; CASH; 3.
DR SMART; SM00256; FBOX; 1.
DR SMART; SM00710; PbH1; 19.
DR SMART; SM00396; ZnF_UBR1; 1.
DR SUPFAM; SSF81383; F-box domain; 1.
DR SUPFAM; SSF51126; Pectin lyase-like; 3.
DR PROSITE; PS50181; FBOX; 1.
DR PROSITE; PS51157; ZF_UBR; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000007801};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 365..411
FT /note="F-box"
FT /evidence="ECO:0000259|PROSITE:PS50181"
FT DOMAIN 1091..1162
FT /note="UBR-type"
FT /evidence="ECO:0000259|PROSITE:PS51157"
FT ZN_FING 1091..1162
FT /note="UBR-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00508"
FT REGION 1..112
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 133..164
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 184..301
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 34..78
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 94..112
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 184..300
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1185 AA; 124712 MW; FF9061C82273F9C5 CRC64;
MPSASFTSSR TYVRRSRRKG ANRIAMPNRP SGNIMDPMLQ QNVSAAAGAG SGPSTSGASG
SSNATSSSSS SSSSAAAGTA AAAPPAPAVA SGSSEYFDSG QGSSSNASAG AAAGASSSGL
AAIVYNALQM MDTTENSGAG SSGAASSTPP VSSSSKSTCA TATAGSSTAS TSAAAAAAAA
AASSAVSASS SHQSPYDLRR KISSSSHEQW GSSSSTAVLV GPSSSSPPLV NPGASPSSSS
SSSSTSSSSS GSSSSSSSSS SASSANVQAP STSATFPVNN APTTGATLAQ PPNVHSSVPQ
QHCGALPVGA AIEDNNYMLP ARKRSRRLYT QSGEMGATAG GASGEASGAG TSAAGSAGCA
PTAAQYLQYE LPDEVLLAIF SYLMEQDLCR LALVCKRFNT IANDTELWKR LYQSVFEYDL
PLFNPELCKF VFEKPEESEY ANPWKESFRQ LYRGVHVRPG YQERRSSGRS IVFFNTIQAA
LDYPEDRAAA GAFASAGAGA GNVSAGLSNT SASAGSNGSG GGASVNALVN IYEEQVAPTE
HPGPLIFLHA GHYKGEYLFI DSDVALVGAA PGNVAESVIL EREAGSTVMF VEGAKYAYVG
YLTLKFSPEV TSTVSHHKHY CLDIGENCSP TVDNCIIRST SVVGAAVCVG GVNANPVIRN
CDISDCENVG LYVTDYAQGT YEHNEISRNA LAGIWVKNFA SPIMRENHIH HGRDVGIFTF
ENGMGYFEKN DIHNNRIAGF EVKAGANPTV VKCEIHHGQT GGIYVHENGL GQFIENRIHS
NNFAGVWITS NSNPTIRKNE IYNGHQGGVY IFGEGRGLIE HNNIYGNALA GIQIRTNSDP
IVRHNKIHHG QHGGIYVHEK GQGLIEENEV YSNTLAGVWI TTGSTPVLRR NRIHSGKQVG
VYFYDNGHGK LEDNDIFNHL YSGVQIRTGS NPVIRGNKIW GGQNGGVLVY NGGLGLLEQN
EIFDNAMAGV WIKTDSNPTL KRNKIYDGRD GGICIFNGGK GILEENDIFR NTQAGVLIST
QSHPILRRNR IYDGQAAGVE ITNNATATLE HNQIFKNKFG GLCLASGVQP ITRGNNIFNN
EDEVEKAVSS GQCLYKISSY TSFPMHDFYR CQTCNTTDRN AICVNCIKNC HAGHDVEFIR
HDRFFCDCGA GTLSNQCQLQ GEPTQDTDTL YDSAAPMESH TLMVN
//
